11-beta HSD1 / HSD11B1 antibody

Principal name

11-beta HSD1 / HSD11B1 antibody

Alternative names for 11-beta HSD1 / HSD11B1 antibody

11-beta-hydroxysteroid dehydrogenase 1, HSD11, HSD11L, 11-DH, Corticosteroid 11-beta-dehydrogenase isozyme 1

SwissProt ID

P16232 (Rat), P28845 (Human), P50172 (Mouse), P51975 (Sheep), Q6QLL4 (Cavpo), Q7M3I4 (Rabit)

Gene ID

3290 (HSD11B1), 15483 (Hsd11b1), 25116

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Ms (Mouse), Por (Porcine), Rb (Rabbit), Rt (Rat), African clawed frog, Chimp (Chimpanzee), Sh (Sheep), Eq (Equine), GP (Guinea Pig)

Available hosts

Mouse, Goat, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C)

Background of 11-beta HSD1 / HSD11B1 antibody

HSD11B1 is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, HSD11B1 can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children.The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Two transcript variants encoding the same protein have been found for this gene.

General readings

Paterson JM, Morton NM, Fievet C, Kenyon CJ, Holmes MC, Staels B, Seckl JR, Mullins JJ. Metabolic syndrome without obesity: Hepatic overexpression of 11betahydroxysteroid dehydrogenase type 1 in transgenic mice. Proc Natl Acad Sci U S A. 2004 May 4;101(18):7088-93.

Items 1 to 20 of 23 total

per page
Page:
  1. 1
  2. 2

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

11-beta HSD1 / HSD11B1 antibody

  Goat Polyclonal Antibody against HSD11B1 / HDL  
TA302508 (0.3µg/ml) staining of Human Liver lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Bov, Chimp, Hu, Sh WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

11-beta HSD1 / HSD11B1 antibody

  Rabbit polyclonal antibody to HSD11B1 (hydroxysteroid (11-beta) dehydrogenase 1)  
Sample (30 ug of whole cell lysate). A: Hep G2 . 12% SDS PAGE. TA308504 diluted at 1:1000. Rabbit IgG Aff - Purified Hu, Sh C, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

11-beta HSD1 / HSD11B1 antibody

  Rabbit polyclonal anti-HSD11B1 antibody  
Western blot analysis of extracts from HuvEc cells, using HSD11B1 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

11-beta HSD1 / HSD11B1 antibody

  Rabbit Polyclonal Anti-HSD11B1 Antibody  
WB Suggested Anti-HSD11B1 Antibody Titration: 1 ug/ml; Positive Control: Fetal liver cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Sh P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

11-beta HSD1 / HSD11B1 antibody

11-beta HSD1 / HSD11B1 Goat Aff - Purified Ms, Rt E, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

11-beta HSD1 / HSD11B1 antibody

Formalin-Fixed, Paraffin-Embedded Human Lung, Macrophages stained with HSD11B1 antibody Cat.-No AP31830PU-N Rabbit IgG Aff - Purified Hu, Ms, Rt P, WB
50 µl / €470.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

HSD11B1 - human gene knockout kit via CRISPR

HSD11B1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

HSD11B1 - human gene knockout kit via CRISPR

HSD11B1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

HSD11B1 - human gene knockout kit via CRISPR

HSD11B1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

HSD11B1 - human gene knockout kit via CRISPR

HSD11B1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Hsd11b1 - mouse gene knockout kit via CRISPR

Hsd11b1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Hsd11b1 - mouse gene knockout kit via CRISPR

Hsd11b1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Hsd11b1 - mouse gene knockout kit via CRISPR

Hsd11b1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Hsd11b1 - mouse gene knockout kit via CRISPR

Hsd11b1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

11-beta HSD1 / HSD11B1 (transcript variant 1)

  Recombinant protein of human hydroxysteroid (11-beta) dehydrogenase 1 (HSD11B1), transcript variant 1  
11-beta HSD1 / HSD11B1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

11-beta HSD1 / HSD11B1 (transcript variant 2)

  Recombinant protein of human hydroxysteroid (11-beta) dehydrogenase 1 (HSD11B1), transcript variant 2  
11-beta HSD1 / HSD11B1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, HSD11B1 (mGFP-tagged) - Human hydroxysteroid (11-beta) dehydrogenase 1 (HSD11B1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, HSD11B1 (mGFP-tagged) - Human hydroxysteroid (11-beta) dehydrogenase 1 (HSD11B1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €960.00
  OriGene Technologies, Inc.

Lenti ORF particles, HSD11B1 (mGFP-tagged) - Human hydroxysteroid (11-beta) dehydrogenase 1 (HSD11B1), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, HSD11B1 (mGFP-tagged) - Human hydroxysteroid (11-beta) dehydrogenase 1 (HSD11B1), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €960.00
  OriGene Technologies, Inc.

Lenti ORF particles, HSD11B1 (Myc-DDK tagged) - Human hydroxysteroid (11-beta) dehydrogenase 1 (HSD11B1), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, HSD11B1 (Myc-DDK tagged) - Human hydroxysteroid (11-beta) dehydrogenase 1 (HSD11B1), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €860.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Hsd11b1 (GFP-tagged) - Mouse hydroxysteroid 11-beta dehydrogenase 1 (Hsd11b1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, Hsd11b1 (GFP-tagged) - Mouse hydroxysteroid 11-beta dehydrogenase 1 (Hsd11b1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Items 1 to 20 of 23 total

per page
Page:
  1. 1
  2. 2
  • LinkedIn