14-3-3 protein epsilon antibody

Principal name

14-3-3 protein epsilon antibody

Alternative names for 14-3-3 protein epsilon antibody

14-3-3E, YWHAE

SwissProt ID

P62258 (Human), P62259 (Mouse), P62260 (Rat), P62261 (Bovin), P62262 (Sheep), Q5ZMT0 (Chick)

Gene ID

7531 (YWHAE), 22627 (Ywhae)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Chk (Chicken), Rb (Rabbit), Sh (Sheep), Can (Canine), Ze (Zebrafish), African clawed frog, Mky (Monkey)

Available hosts

Mouse, Rabbit, Chicken

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of 14-3-3 protein epsilon antibody

14-3-3 proteins regulate many cellular processes relevant to cancer biology, notably apoptosis, mitogenic signaling and cell-cycle checkpoints. Seven isoforms comprise this family of signaling intermediates, denoted 14-3-3 beta, gamma, episilon, zeta, eta, theta and sigma. 14-3-3 proteins form dimers that present two binding sites for ligand proteins, thereby bringing together two proteins that may not otherwise associate. These ligands largely share a 14-3-3 consensus binding motif and exhibit serine/threonine phosphorylation. 14-3-3 proteins function in broad regulation of these ligand proteins, by cytoplasmic sequestration, occupation of interaction domains and import/export sequences, prevention of degradation, activation/repression of enzymatic activity and facilitation of protein modification, and thus loss of expression contributes to a vast array of pathogenic cellular activities.

General readings

Oriente F, et al.(2005) J Biol Chem. ;280(49):40642-9.
Conklin D, et al.(2005) PNAS ,92(17):7892-7896.

4 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

14-3-3 protein epsilon antibody

Immunohistochemistry: AM09042PU-N YWHAE antibody staining of Formalin-Fixed, Paraffin-Embedded Human Lung at 5 µg/ml followed by biotinylated anti-mouse IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Mouse IgG2a 5A5 Purified Hu, Ms E, P, WB
0.1 ml / €310.00
  Acris Antibodies GmbH

14-3-3 protein epsilon antibody

Immunohistochemistry: AM09042PU-N YWHAE antibody staining of Formalin-Fixed, Paraffin-Embedded Human Lung at 5 µg/ml followed by biotinylated anti-mouse IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Mouse IgG2a 5A5 Purified Hu, Ms E, P, WB

Regular Price: 50 µl / €230.00

Special Price: 50 µl / €161.00

  Acris Antibodies GmbH

14-3-3 protein epsilon antibody

14-3-3 protein epsilon Rabbit IgG Purified Hu, Ms, Rt P, WB
0.1 ml / €240.00
  Bioss, Inc.

14-3-3 protein epsilon pThr232 antibody

14-3-3 protein epsilon Rabbit IgG Purified Hu, Ms, Rt P, WB
0.1 ml / €250.00
  Bioss, Inc.

4 Item(s)

per page
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