14-3-3 protein epsilon antibody

Principal name

14-3-3 protein epsilon antibody

Alternative names for 14-3-3 protein epsilon antibody

14-3-3E, YWHAE

Selected pictures

14-3-3 protein epsilon antibody - AP22883SU-N
AP22883SU-N - Human Breast (formalin-fixed, paraffin-embedded) stained with YWHAE antibody AP22883SU-N followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.
14-3-3 protein epsilon antibody - ARP32088_P050
ARP32088_P050 - Human brain stem; . Sample Type :. Human brain stem cells. Primary Antibody Dilution :. 1:500. Secondary Antibody :. Goat anti-rabbit Alexa-Fluor 594. Secondary Antibody Dilution :. 1:1000. Color/Signal Descriptions :. Ywhae: Red DAPI:Blue. Gene Name :. Ywhae. Submitted by :. Dr. Yuzhi Chen, University of Arkansas for Medical Science; Ywhae antibody - C-terminal region (ARP32088_P050) in Human brain stem cells using Immunohistochemistry

SwissProt ID

P62258 (Human), P62259 (Mouse), P62260 (Rat), P62261 (Bovin), P62262 (Sheep), Q5ZMT0 (Chick)

Gene ID

7531 (YWHAE), 22627 (Ywhae)

Available reactivities

Sh (Sheep), Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), Chk (Chicken), Rt (Rat), Ze (Zebrafish), African clawed frog, Rb (Rabbit), Mky (Monkey)

Available hosts

Rabbit, Chicken, Mouse, Sheep

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of 14-3-3 protein epsilon antibody

14-3-3 proteins regulate many cellular processes relevant to cancer biology, notably apoptosis, mitogenic signaling and cell-cycle checkpoints. Seven isoforms comprise this family of signaling intermediates, denoted 14-3-3 beta, gamma, episilon, zeta, eta, theta and sigma. 14-3-3 proteins form dimers that present two binding sites for ligand proteins, thereby bringing together two proteins that may not otherwise associate. These ligands largely share a 14-3-3 consensus binding motif and exhibit serine/threonine phosphorylation. 14-3-3 proteins function in broad regulation of these ligand proteins, by cytoplasmic sequestration, occupation of interaction domains and import/export sequences, prevention of degradation, activation/repression of enzymatic activity and facilitation of protein modification, and thus loss of expression contributes to a vast array of pathogenic cellular activities.

General readings

Oriente F, et al.(2005) J Biol Chem. ;280(49):40642-9.
Conklin D, et al.(2005) PNAS ,92(17):7892-7896.

4 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  
H00007531-A01

14-3-3 protein epsilon antibody

14-3-3 protein epsilon Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.
MAB1125

14-3-3 protein epsilon antibody

Western blot analysis of mouse brain extracts ( 50 µg ) were resolved by SDS - PAGE , transferred to NC membrane and probed with YWHAE monoclonal antibody , clone 5A5 ( 1 : 1000 ) ( Cat # MAB1125 ) . Proteins were visualized using a goat anti - mouse secondary antibody conjugated to HRP and an ECL detection system. Mouse IgG2a 5A5 Hu E, WB
0.1 ml / €390.00
  Abnova Taiwan Corp.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  
H00007531-P01-10

14-3-3 protein epsilon

14-3-3 protein epsilon Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €370.00
  Abnova Taiwan Corp.
H00007531-P01-25

14-3-3 protein epsilon

14-3-3 protein epsilon Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €500.00
  Abnova Taiwan Corp.

4 Item(s)

per page
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