14-3-3 protein gamma antibody
Principal name
14-3-3 protein gamma antibody
Alternative names for 14-3-3 protein gamma antibody
YWHAG, KCIP-1, Protein kinase C inhibitor protein 1
SwissProt ID
P61981 (Human), P61982 (Mouse), P61983 (Rat), P68252 (Bovin), P68253 (Sheep), Q5F3W6 (Chick)
Ncbi ID
NP_036611, NP_036611.2, 9606, NM_018871, NM_019376, NP_061359.2
Available reactivities
Available hosts
Available applications
Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), Immunoprecipitation (IP)
Background of 14-3-3 protein gamma antibody
14-3-3 gamma is a member of the 14-3-3 family which consists of 30 kDa proteins that are involved in multiple protein kinase signalling pathways, regulation of cell cycle progression, cytoskeletal structure, transcription, intracellular trafficking and targeting. Protein interactions with 14-3-3 show distinct preference for its different isoforms and are regulated by phosphorylation of both 14-3-3 and the bound protein.
14-3-3 gamma is thought to play an important role in muscle, being induced by growth factors in human vascular smooth muscle cells, and being expressed in skeletal and heart muscles. An example is the gamma isoform binds musclespecific receptor tyrosine kinase regulating synaptic gene transmission. The gamma isoform binds amyloid betaprotein precursor intracellular domain fragment (AICD) and FE65, facilitating FE65dependent gene transactivation. The binding of 14-3-3 gamma to glial fibrillary acidic protein is important in the regulation of glial filaments. 14-3-3 gamma binds and may regulate CDK11 during the cell cycle and apoptosis. The gamma isoform is lowered in foetal Downs syndrome brains.
General readings
1. Martin, H. et al. (1993) Antibodies against major brain isoforms of 14-3-3 protein. An antibody specific for the Nacetylated aminoterminus of a protein. FEBS 331: 296 - 303.
2. Aitken, A. et al. (2006) 14-3-3 proteins: A historic overview. Seminars in Cancer Biology 16: 162 - 172.
3. Wang, Z. et al. (2011) The prognostic value of 14-3-3 isoforms in vulvar squamous cell carcinoma cases: 14-3-3ß and e are independent prognostic factors for these tumors.
PLoS One. 6: e24843.



























Primary Antibodies
Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
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TA301661 | 14-3-3 protein gamma antibody |
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Mouse Monoclonal Antibody against 14-3-3 gamma (HS23) | |||||||
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Mouse | IgG1 | HS23 | Purified | Bov, Chk, Hu, Ms, Rt, Ze | ICC/IF, WB |
0.1 ml /
€451.00
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OriGene Technologies, Inc. | |||||||
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TA312741 | 14-3-3 protein gamma antibody |
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Rabbit polyclonal anti-14-3-3 gamma antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt | E, ICC/IF, P, WB |
0.1 ml /
€335.00
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OriGene Technologies, Inc. | |||||||
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TA322404 | 14-3-3 protein gamma antibody |
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Anti-YWHAG Rabbit Polyclonal Antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt | E, P, WB |
0.1 ml /
€335.00
|
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OriGene Technologies, Inc. | |||||||
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TA322405 | 14-3-3 protein gamma antibody |
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Anti-YWHAG Rabbit Polyclonal Antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt | E, P, WB |
0.1 ml /
€335.00
|
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OriGene Technologies, Inc. | |||||||
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AM26569AF-N | 14-3-3 protein gamma (1-12) antibody |
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Mouse | IgG2a | KC21 | Azide Free | Hu, Ms, Rt | IP, WB |
0.1 mg /
€350.00
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Acris Antibodies GmbH | |||||||
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AP17846PU-N | 14-3-3 protein gamma antibody |
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Rabbit | Hu, Ms | WB |
0.4 ml /
€370.00
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Acris Antibodies GmbH | |||||||
AP17847PU-N | 14-3-3 protein gamma (N-term) antibody |
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Rabbit | Hu, Ms | WB |
0.4 ml /
€370.00
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Acris Antibodies GmbH | |||||||
AP20539PU-N | 14-3-3 protein gamma antibody |
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Rabbit | Aff - Purified | Hu, Ms, Rt | ICC/IF, P, WB |
0.1 mg /
€350.00
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Acris Antibodies GmbH | |||||||
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