14-3-3 protein gamma antibody

Principal name

14-3-3 protein gamma antibody

Alternative names for 14-3-3 protein gamma antibody

YWHAG, KCIP-1, Protein kinase C inhibitor protein 1

Selected pictures

14-3-3 protein gamma antibody - AP20539PU-N
AP20539PU-N - Immunohistochemistry (IHC) analyzes of 14-3-3 gamma antibody (Cat.-No.: AP20539PU-N) in paraffin-embedded human brain tissue.
14-3-3 protein gamma antibody - AP20539PU-N 14-3-3 protein gamma
AP20539PU-N 14-3-3 protein gamma - Western blot analysis of 14-3-3 gamma Antibody (Cat.-No AP20539PU-N) in extracts from Hela cells at 1/500 dilution.

SwissProt ID

P61981 (Human), P61982 (Mouse), P61983 (Rat), P68252 (Bovin), P68253 (Sheep), Q5F3W6 (Chick)

Gene ID

7532 (YWHAG)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Chk (Chicken), Ze (Zebrafish), Sh (Sheep)

Available hosts

Rabbit, Mouse

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunoprecipitation (IP), ELISA (detection) (E(detection))

Background of 14-3-3 protein gamma antibody

14-3-3 gamma is a member of the 14-3-3 family which consists of 30 kDa proteins that are involved in multiple protein kinase signalling pathways, regulation of cell cycle progression, cytoskeletal structure, transcription, intracellular trafficking and targeting. Protein interactions with 14-3-3 show distinct preference for its different isoforms and are regulated by phosphorylation of both 14-3-3 and the bound protein.
14-3-3 gamma is thought to play an important role in muscle, being induced by growth factors in human vascular smooth muscle cells, and being expressed in skeletal and heart muscles. An example is the gamma isoform binds musclespecific receptor tyrosine kinase regulating synaptic gene transmission. The gamma isoform binds amyloid betaprotein precursor intracellular domain fragment (AICD) and FE65, facilitating FE65dependent gene transactivation. The binding of 14-3-3 gamma to glial fibrillary acidic protein is important in the regulation of glial filaments. 14-3-3 gamma binds and may regulate CDK11 during the cell cycle and apoptosis. The gamma isoform is lowered in foetal Downs syndrome brains.

General readings

1. Martin, H. et al. (1993) Antibodies against major brain isoforms of 14-3-3 protein. An antibody specific for the Nacetylated aminoterminus of a protein. FEBS 331: 296 - 303.
2. Aitken, A. et al. (2006) 14-3-3 proteins: A historic overview. Seminars in Cancer Biology 16: 162 - 172.
3. Wang, Z. et al. (2011) The prognostic value of 14-3-3 isoforms in vulvar squamous cell carcinoma cases: 14-3-3ß and e are independent prognostic factors for these tumors.
PLoS One. 6: e24843.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  
12381-1-AP

14-3-3 protein gamma antibody

Immunofluorescent analysis of MDCK cells using 12381-1-AP( 14 3 3GAMMA Antibody) at dilution of 1:25 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L) Rabbit IgG Aff - Purified Can, Hu, Ms, Rt E, ICC/IF, IP, WB
0.15 ml / €285.00
  Proteintech Group, Inc.

Tested with siRNA

AM09044PU-N

14-3-3 protein gamma antibody

Immunohistochemistry: AM09044PU-N 14-3-3 gamma antibody staining of Formalin-Fixed, Paraffin-Embedded Human Heart at 5 µg/ml followed by biotinylated anti-mouse IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Mouse IgG2b J3H10 Purified Hu, Ms E, WB
0.1 ml / €310.00
  Acris Antibodies GmbH
AM09044PU-S

14-3-3 protein gamma antibody

Immunohistochemistry: AM09044PU-N 14-3-3 gamma antibody staining of Formalin-Fixed, Paraffin-Embedded Human Heart at 5 µg/ml followed by biotinylated anti-mouse IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Mouse IgG2b J3H10 Purified Hu, Ms E, WB
50 µl / €230.00
  Acris Antibodies GmbH
GTX110629

14-3-3 protein gamma antibody

Immunohistochemical analysis of paraffin-embedded CA922 xenograft, using 14-3-3 gamma(GTX110629) antibody at 1:500 dilution. Rabbit Aff - Purified Hu, Ms ICC/IF, P, WB
0.1 ml / €350.00
  GeneTex Inc.
GTX113298

14-3-3 protein gamma antibody

Immunohistochemical analysis of paraffin-embedded DLD1 xenograft, using 14-3-3 gamma(GTX113298) antibody at 1:500 dilution. Rabbit Aff - Purified Hu, Ms ICC/IF, P, WB
0.1 ml / €350.00
  GeneTex Inc.


Sample size available for 25µl / 119€
read more…

H00007532-M02

14-3-3 protein gamma antibody

YWHAG monoclonal antibody (M02), clone 6A10. Western Blot analysis of YWHAG expression in IMR-32 ( Cat # L008V1 ). Mouse IgG2b 6A10 Purified Hu, Ms, Rt E, WB
0.1 mg / €360.00
  Abnova Taiwan Corp.
AM26569AF-N

14-3-3 protein gamma (1-12) antibody

Immunoprecipitation of 14-3-3γ from A431 cells with mouse IgG2a (1) or AM26569AF-N (2). After immunoprecipitated with the antibody, immunocomplex was resolved on SDS-PAGE and immunoblotted with AM26569AF-N. Mouse IgG2a KC21 Azide Free Hu, Ms, Rt IP, WB
0.1 mg / €330.00
  Acris Antibodies GmbH
AM50336PU-N

14-3-3 protein gamma antibody

14-3-3 protein gamma Mouse IgG1 AT4B9 Purified Hu E, WB
0.1 ml / €310.00
  Acris Antibodies GmbH
AM50336PU-S

14-3-3 protein gamma antibody

14-3-3 protein gamma Mouse IgG1 AT4B9 Purified Hu E, WB
50 µl / €220.00
  Acris Antibodies GmbH
AP05567SU-N

14-3-3 protein gamma antibody

Western blots of 14-3-3 isoforms in HEK293 cell extracts using 14-3-3 antibodies.
Lane 1: anti-gamma 14-3-3 (AP05567SU-N)
Lane 2: anti-zeta 14-3-3 (AP05572SU-N)
Lane 3: anti-C-epsilon-14-3-3 (AP05565SU-N)
Lane 4: anti-N-epsilon-14-3-3 (AP05568SU-N)
Lane 5: anti-eta 14-3-3. (AP05566SU-N)

The 14-3-3 isoforms run at 30kDa except epsilon 14-3-3 Rabbit IgG Serum Bov, Chk, Hu, Ms, Rt, Sh E, P, WB
0.1 ml / €470.00
  Acris Antibodies GmbH
AP17846PU-N

14-3-3 protein gamma antibody

Western blot analysis of YWHAG Antibody (Center) (AP17846PU-N) in mouse cerebellum tissue lysates (35ug/lane). YWHAG (arrow) was detected using the purified Pab. Rabbit Hu, Ms WB
0.4 ml / €360.00
  Acris Antibodies GmbH
AP17847PU-N

14-3-3 protein gamma (N-term) antibody

Western blot analysis of YWHAG Antibody (N-term) (AP17847PU-N) in A375 cell line and mouse cerebellum tissue lysates (35ug/lane). YWHAG (arrow) was detected using the purified Pab. Rabbit Hu, Ms WB
0.4 ml / €360.00
  Acris Antibodies GmbH
AP20539PU-N

14-3-3 protein gamma antibody

Immunohistochemistry (IHC) analyzes of 14-3-3 gamma antibody (Cat.-No.: AP20539PU-N) in paraffin-embedded human brain tissue. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH
GTX14117

14-3-3 protein gamma antibody

14-3-3 protein gamma Mouse IgG 3F8 Purified Hu IP, WB
0.25 ml / €380.00
  GeneTex Inc.
GTX14118

14-3-3 protein gamma antibody

14-3-3 protein gamma Mouse IgG1 3F8 Purified Hu IP, WB
50 µl / €350.00
  GeneTex Inc.
GTX30643

14-3-3 protein gamma antibody

Western Blot: 14-3-3 gamma Antibody (HS23) [GTX30643] - 14-3-3 gamma detected in lysates using GTX30643. Lane 1: HeLa cell lysate, Lanes 2 and 3: bengamide treated lysates (8h and 24h, respectively). Mouse IgG1 HS23 Purified Hu WB
0.1 ml / €410.00
  GeneTex Inc.
GTX48540

14-3-3 protein gamma antibody

Immunocytochemistry: 14-3-3 gamma Antibody (HS23)  - Detection of 14-3-3 gamma (green) in HepG2 cells using GTX48540 Nuclei (Blue) are counterstained with Hoechst 33258. Mouse IgG1 [HS23 Ascites Bov, Chk, Hu, Ms, Rt, Ze
50 µl / €290.00
  GeneTex Inc.
H00007532-A01

14-3-3 protein gamma antibody

14-3-3 protein gamma Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.
H00007532-A02

14-3-3 protein gamma antibody

14-3-3 protein gamma Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.
H00007532-D01P

14-3-3 protein gamma antibody

14-3-3 protein gamma Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

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