14-3-3 protein zeta/delta antibody

Principal name

14-3-3 protein zeta/delta antibody

Alternative names for 14-3-3 protein zeta/delta antibody

YWHAZ, KCIP-1, Protein kinase C inhibitor protein 1

Selected pictures

14-3-3 protein zeta/delta antibody - A0001-1 14-3-3 protein zeta/delta
A0001-1 14-3-3 protein zeta/delta - Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using 14-3-3 zeta (Phospho-Ser58) Antibody. The picture on the right is treated with the synthesized peptide.
14-3-3 protein zeta/delta antibody - A0001-1 14-3-3 protein zeta/delta
A0001-1 14-3-3 protein zeta/delta - Immunofluorescence analysis of HeLa cells treated with PMA 125ng/ml 30', using 14-3-3 zeta (Phospho-Ser58) Antibody. The picture on the right is treated with the synthesized peptide.

SwissProt ID

P29361 (Sheep), P63101 (Mouse), P63102 (Rat), P63103 (Bovin), P63104 (Human), Q5ZKC9 (Chick), Q91896 (Xenla)

Gene ID

7534 (YWHAZ), 25578 (Ywhaz)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Chk (Chicken), Ze (Zebrafish), African clawed frog, Sh (Sheep), Dros (Drosophila), Por (Porcine)

Available hosts

Rabbit, Mouse

Available applications

Paraffin Sections (P), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), ELISA (detection) (E(detection)), Frozen Sections (C), Flow Cytometry (F)

Background of 14-3-3 protein zeta/delta antibody

It is a member of the 14-3-3 family which consists of 30kDa proteins that are involved in multiple protein kinase signaling pathways, regulation of cell cycle progression, cytoskeletal structure, transcription, intracellular trafficking and targeting. Protein interactions with 14-3-3 show distinct preference for its different isotypes and are regulated by phosphorylation of both 14-3-3 and the bound protein. 14-3-3 zeta is a susceptibility gene for paranoid schizophrenia and is overexpressed in the temporal cortex of cognitively impared Alzheimers patients. The protein binds yeast Sps1/Ste20-related kinase 1 (YSK1) and localizes to the golgi, possibly linking YSK1 signaling, protein transport, cell adhesion and migration. It co-localizes with epidermal growth factor receptor to the plasma membrane following epidermal growth factor signaling. The zeta isoform is involved in MAPKAPK2-mediated phosphorylation which may have a role in p38 MAPK-dependent inflammation. When bound to ADAM 22, 14-3-3 zeta is involved in cell adhesion. 14-3-3 zeta also interacts with cofilin, LIM-domain-containing protein kinase 1, protein kinase B/Akt and GPI alpha.

General readings

1. Simeone P  et al. A unique four-hub protein cluster associates to glioblastoma progression.PLoS One 9:e103030 (2014). IHC-P ; Human .PubMed: 25050814
2. Ota S  et al. Contribution of fetal ANXA5 gene promoter polymorphisms to the onset of pre-eclampsia. Placenta 34:1202-10 (2013). Human .PubMed: 24140079
3. Deng MY  et al. Frontal-Subcortical Protein Expression following Prenatal Exposure to Maternal Inflammation. PLoS One 6:e16638 (2011). WB ; Mouse .PubMed: 21347362
4. Broadstock M  et al. Synaptic protein expression is regulated by a pro-oxidant diet in APPxPS1 mice. J Neural Transm : (2011). WB ; Mouse .PubMed: 22057511
5. Koseki N  et al. 17ß-estradiol prevents reduction of retinal phosphorylated 14-3-3 zeta protein levels following a neurotoxic insult. Brain Res : (2011). WB, ICC/IF, IHC-P ; Rat .PubMed: 22154405
6. Bansal A  et al. Proteomic analysis reveals late exercise effects on cardiac remodeling following myocardial infarction. J Proteomics 73:2041-9 (2010). WB ; Rat .PubMed: 20601275

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  
GTX101075

14-3-3 protein zeta/delta antibody

14-3-3 zeta antibody detects 14-3-3 zeta protein at cytosol on mouse colon by immunohistochemical analysis. Sample: Paraffin-embedded mouse colon. 14-3-3 zeta antibody (GTX101075) dilution: 1:500. Rabbit Aff - Purified Hu, Ms ICC/IF, P, WB
0.1 ml / €350.00
  GeneTex Inc.


Sample size available for 25µl / 119€
read more…

AP15332PU-M

14-3-3 protein zeta/delta (134-149) antibody

Human breast ca. stained with Anti-14-3-3 zeta, cat# AP15332PU Rabbit Purified Hu, Ms, Rt P, WB
0.5 ml / €350.00
  Acris Antibodies GmbH
AP15332PU-N

14-3-3 protein zeta/delta (134-149) antibody

Human breast ca. stained with Anti-14-3-3 zeta, cat# AP15332PU Rabbit Purified Hu, Ms, Rt P, WB
1 ml / €510.00
  Acris Antibodies GmbH
AP15332PU-S

14-3-3 protein zeta/delta (134-149) antibody

Human breast ca. stained with Anti-14-3-3 zeta, cat# AP15332PU Rabbit Purified Hu, Ms, Rt P, WB
0.1 ml / €190.00
  Acris Antibodies GmbH
14881-1-AP

14-3-3 protein zeta/delta antibody

Mouse brain tissue were subjected to SDS PAGE followed by western blot with 14881-1-AP(YWHAZ antibody) at dilution of 1:400 Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
0.15 ml / €285.00
  Proteintech Group, Inc.
AP02457PU-N

14-3-3 protein zeta/delta pSer58 antibody

Figure 1. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using 14-3-3 zeta (Phospho-Ser58) antibody AP02457PU. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 ml / €320.00
  Acris Antibodies GmbH
AP02457PU-S

14-3-3 protein zeta/delta pSer58 antibody

Figure 1. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using 14-3-3 zeta (Phospho-Ser58) antibody AP02457PU. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
50 µl / €240.00
  Acris Antibodies GmbH
AP02701PU-N

14-3-3 protein zeta/delta antibody

Figure 1. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using 14-3-3 zeta antibody AP02701PU. Rabbit Aff - Purified Hu, Ms P, WB
0.1 ml / €270.00
  Acris Antibodies GmbH
AP02701PU-S

14-3-3 protein zeta/delta antibody

Figure 1. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using 14-3-3 zeta antibody AP02701PU. Rabbit Aff - Purified Hu, Ms P, WB
50 µl / €230.00
  Acris Antibodies GmbH
AP05572SU-N

14-3-3 protein zeta/delta (N-term acetylated) antibody

Western blots of 14-3-3 isoforms in HEK293 cell extracts using 14-3-3 antibodies.
Lane 1: anti-gamma 14-3-3 (AP05567SU-N)
Lane 2: anti-zeta 14-3-3 (AP05572SU-N)
Lane 3: anti-C-epsilon-14-3-3 (AP05565SU-N)
Lane 4: anti-N-epsilon-14-3-3 (AP05568SU-N)
Lane 5: anti-eta 14-3-3. (AP05566SU-N)

The 14-3-3 isoforms run at 30kDa except epsilon 14-3-3 Rabbit IgG Serum Bov, Chk, Hu, Ms, Rt, Sh E, P, WB
0.1 ml / €470.00
  Acris Antibodies GmbH
AP06623PU-N

14-3-3 protein zeta/delta antibody

Immunohistochemistry (IHC) analyzes of 14-3-3 ζ/δ antibody in paraffin-embedded human colon carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH
AP07437PU-N

14-3-3 protein zeta/delta pSer58 antibody

Lung, respiratory epithelium: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Hu, Ms, Rt P, WB
50 µg / €470.00
  Acris Antibodies GmbH
AP08195PU-N

14-3-3 protein zeta/delta antibody

Brain, cerebellum: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Hu, Ms, Rt P, WB
50 µg / €470.00
  Acris Antibodies GmbH
AP20192PU-N

14-3-3 protein zeta/delta antibody

Immunohistochemistry (IHC) analyzes of 14-3-3 ζ (pVal52) antibody (Cat.-No AP20192PU-N) in paraffin-embedded human breast carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, IP, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH
AP20468PU-N

14-3-3 protein zeta/delta antibody

Immunohistochemistry (IHC) analyzes of 14-3-3 zeta antibody (Cat.-No AP20468PU-N) in paraffin-embedded human brain tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH
AP54747SU-N

14-3-3 protein zeta/delta pSer184 antibody

14-3-3 protein zeta/delta Rabbit Serum Hu, Ms, Rt E, P, WB
0.2 ml / €400.00
  Acris Antibodies GmbH
AP55906PU-N

14-3-3 protein zeta/delta pThr232 antibody

Western blot analysis of extracts from Jurkat cells treated with UV using Phospho-14-3-3 zeta/ delta (Thr232) antibody AP55906PU-N.The lane on the right is treated with the antigen-specific peptide. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 ml / €340.00
  Acris Antibodies GmbH
AP55906PU-S

14-3-3 protein zeta/delta pThr232 antibody

Western blot analysis of extracts from Jurkat cells treated with UV using Phospho-14-3-3 zeta/ delta (Thr232) antibody AP55906PU-N.The lane on the right is treated with the antigen-specific peptide. Rabbit Aff - Purified Hu, Ms, Rt WB
50 µl / €270.00
  Acris Antibodies GmbH
GTX50519

14-3-3 protein zeta/delta antibody

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using 14-3-3 zeta Antibody (GTX50519) (left) or the same antibody preincubated with blocking peptide (right). Rabbit Aff - Purified Hu, Ms, Rt C, WB
0.1 ml / €370.00
  GeneTex Inc.
GTX50712

14-3-3 protein zeta/delta antibody

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using 14-3-3 zeta (Phospho-Ser58) Antibody (GTX50712) (left) or the same antibody preincubated with blocking peptide (right). Rabbit Aff - Purified Hu, Ms, Rt C, ICC/IF, WB
0.1 ml / €370.00
  GeneTex Inc.

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