14-3-3 protein zeta/delta antibody
Principal name
14-3-3 protein zeta/delta antibody
Alternative names for 14-3-3 protein zeta/delta antibody
YWHAZ, KCIP-1, Protein kinase C inhibitor protein 1
SwissProt ID
P29361 (Sheep), P63101 (Mouse), P63102 (Rat), P63103 (Bovin), P63104 (Human), Q5ZKC9 (Chick), Q91896 (Xenla)
Ncbi ID
NP_001129171.1, 9940, 9606, NP_003397, NP_001129171, NP_001129172, NP_001129173, NP_001129174, NP_035870.1, NM_011740, NM_013011, NM_003406, NM_145690, NM_001135701, NM_001135702
Available reactivities
Available hosts
Available applications
Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Immunoprecipitation (IP), ELISA (detection) (E(detection))
Background of 14-3-3 protein zeta/delta antibody
It is a member of the 14-3-3 family which consists of 30kDa proteins that are involved in multiple protein kinase signaling pathways, regulation of cell cycle progression, cytoskeletal structure, transcription, intracellular trafficking and targeting. Protein interactions with 14-3-3 show distinct preference for its different isotypes and are regulated by phosphorylation of both 14-3-3 and the bound protein. 14-3-3 zeta is a susceptibility gene for paranoid schizophrenia and is overexpressed in the temporal cortex of cognitively impared Alzheimers patients. The protein binds yeast Sps1/Ste20-related kinase 1 (YSK1) and localizes to the golgi, possibly linking YSK1 signaling, protein transport, cell adhesion and migration. It co-localizes with epidermal growth factor receptor to the plasma membrane following epidermal growth factor signaling. The zeta isoform is involved in MAPKAPK2-mediated phosphorylation which may have a role in p38 MAPK-dependent inflammation. When bound to ADAM 22, 14-3-3 zeta is involved in cell adhesion. 14-3-3 zeta also interacts with cofilin, LIM-domain-containing protein kinase 1, protein kinase B/Akt and GPI alpha.
General readings
1. Martin, H. et al. (1993) Antibodies against major brain isoforms of 14-3-3 protein. An antibody specific for the Nacetylated aminoterminus of a protein. FEBS 331: 296 - 303.
2. Aitken, A. et al. (2006) 14-3-3 proteins: A historic overview. Seminars in Cancer Biology 16: 162 - 172.
3. Wang, Z. et al. (2011) The prognostic value of 14-3-3 isoforms in vulvar squamous cell carcinoma cases: 14-3-3ß and e are independent prognostic factors for these tumors.
PLoS One. 6: e24843.







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Lane2:Mouse brain tissue lysate
Lane3:Rat kidney tissue lysate































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Primary Antibodies
Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
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AP06623PU-N | 14-3-3 protein zeta/delta antibody |
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Rabbit | Aff - Purified | Hu, Ms, Rt | ICC/IF, P, WB |
0.1 mg /
€350.00
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Acris Antibodies GmbH | |||||||
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Published recently! |
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TA314679 | 14-3-3 protein zeta/delta antibody |
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Rabbit polyclonal 14-3-3 zeta (Ser58) antibody(Phospho-specific) | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt | E, ICC/IF, P, WB |
0.1 ml /
€335.00
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OriGene Technologies, Inc. | |||||||
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Highly validated antibody! |
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TA311637 | 14-3-3 protein zeta/delta antibody |
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Rabbit polyclonal 14-3-3 zeta/delta (Ab-232) antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms | E, ICC/IF, P, WB |
0.1 ml /
€335.00
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OriGene Technologies, Inc. | |||||||
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TA314677 | 14-3-3 protein zeta/delta antibody |
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Rabbit polyclonal 14-3-3 beta/zeta (Ab-184/186)) antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms | E, WB |
0.1 ml /
€335.00
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OriGene Technologies, Inc. | |||||||
TA314678 | 14-3-3 protein zeta/delta antibody |
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Rabbit polyclonal anti-14-3-3 zeta antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt | E, WB |
0.1 ml /
€335.00
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OriGene Technologies, Inc. | |||||||
TA323869 | 14-3-3 protein zeta/delta antibody |
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Anti-YWHAZ (Phospho-Ser58) Rabbit Polyclonal Antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt | ICC/IF, P, WB |
0.1 ml /
€335.00
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OriGene Technologies, Inc. | |||||||
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TA323870 | 14-3-3 protein zeta/delta antibody |
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Anti-YWHAZ Rabbit Polyclonal Antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt | P, WB |
0.1 ml /
€335.00
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OriGene Technologies, Inc. | |||||||
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TA325982 | 14-3-3 protein zeta/delta antibody |
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Rabbit Polyclonal 14-3-3 zeta Antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt | WB |
0.1 ml /
€335.00
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OriGene Technologies, Inc. | |||||||
TA325983 | 14-3-3 protein zeta/delta antibody |
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Rabbit Polyclonal 14-3-3 zeta/delta Antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt | WB |
0.1 ml /
€335.00
|
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OriGene Technologies, Inc. | |||||||
TA325984 | 14-3-3 protein zeta/delta antibody |
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Rabbit Polyclonal 14-3-3 zeta (Ser58) Antibody (Phospho-specific) | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt | WB |
0.1 ml /
€335.00
|
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OriGene Technologies, Inc. | |||||||
TA325985 | 14-3-3 protein zeta/delta antibody |
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Rabbit Polyclonal 14-3-3 zeta/ delta (Thr232) Antibody (Phospho-specific) | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt | WB |
0.1 ml /
€335.00
|
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OriGene Technologies, Inc. | |||||||
TA347331 | 14-3-3 protein zeta/delta antibody |
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Rabbit Polyclonal 14-3-3 beta/zeta (YWHAZ) Antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt | WB |
0.1 mg /
€335.00
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OriGene Technologies, Inc. | |||||||
TA347722 | 14-3-3 protein zeta/delta antibody |
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Rabbit Polyclonal 14-3-3 zeta (YWHAZ) Antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt | WB |
0.1 mg /
€335.00
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OriGene Technologies, Inc. | |||||||
AP02457PU-N | 14-3-3 protein zeta/delta pSer58 antibody |
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Rabbit | Aff - Purified | Hu, Ms, Rt | ICC/IF, P, WB |
0.1 mg /
€320.00
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Acris Antibodies GmbH | |||||||
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AP02457PU-S | 14-3-3 protein zeta/delta pSer58 antibody |
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Rabbit | Aff - Purified | Hu, Ms, Rt | ICC/IF, P, WB |
50 µg /
€240.00
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Acris Antibodies GmbH | |||||||
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AP02701PU-N | 14-3-3 protein zeta/delta antibody |
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Rabbit | Aff - Purified | Hu, Ms | P, WB |
0.1 mg /
€320.00
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Acris Antibodies GmbH | |||||||
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AP02701PU-S | 14-3-3 protein zeta/delta antibody |
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Rabbit | Aff - Purified | Hu, Ms | P, WB |
50 µg /
€240.00
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Acris Antibodies GmbH | |||||||
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AP05572SU-N | 14-3-3 protein zeta/delta (N-term acetylated) antibody |
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Rabbit | IgG | Serum | Bov, Chk, Hu, Ms, Rt, Sh | E, P, WB |
0.1 ml /
€480.00
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Acris Antibodies GmbH | |||||||
AP08195PU-N | 14-3-3 protein zeta/delta antibody |
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Rabbit | IgG | Aff - Purified | Hu, Ms, Rt | P, WB |
50 µg /
€430.00
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Acris Antibodies GmbH | |||||||
AP20192PU-N | 14-3-3 protein zeta/delta antibody |
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Rabbit | Aff - Purified | Hu, Ms, Rt | ICC/IF, IP, P, WB |
0.1 mg /
€350.00
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Acris Antibodies GmbH | |||||||
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