7-DHC reductase antibody

Principal name

7-DHC reductase antibody

Alternative names for 7-DHC reductase antibody

7-dehydrocholesterol reductase, DHCR7, D7SR, Sterol Delta(7)-reductase, Putative sterol reductase SR-2

SwissProt ID

O88455 (Mouse), Q5E9J5 (Bovin), Q7ZXH1 (Xenla), Q9UBM7 (Human), Q9Z2Z8 (Rat)

Gene ID

1717 (DHCR7)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C), Enzyme Immunoassay (E), Immunoprecipitation (IP)

Background of 7-DHC reductase antibody

This gene encodes an enzyme that removes the C(7-8) double bond in the B ring of sterols and catalyzes the conversion of 7-dehydrocholesterol to cholesterol. This gene is ubiquitously expressed and its transmembrane protein localizes to the endoplasmic reticulum membrane and nuclear outer membrane. Mutations in this gene cause Smith-Lemli-Opitz syndrome (SLOS); a syndrome that is metabolically characterized by reduced serum cholesterol levels and elevated serum 7-dehydrocholesterol levels and phenotypically characterized by mental retardation, facial dysmorphism, syndactyly of second and third toes, and holoprosencephaly in severe cases to minimal physical abnormalities and near-normal intelligence in mild cases. Alternative splicing results in multiple transcript variants that encode the same protein.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

7-DHC reductase antibody

DHCR7 MaxPab rabbit polyclonal antibody. Western Blot analysis of DHCR7 expression in mouse testis. Rabbit Purified Hu, Ms, Rt E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

7-DHC reductase antibody

Immunohistochemistry-Paraffin: DHCR7 Antibody [NBP1-80740] - Immunohistochemical staining of human pancreas shows strong cytoplasmic positivity in exocrine glandular cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

7-DHC reductase

7-DHC reductase Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

7-DHC reductase

7-DHC reductase Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

DHCR7 293T Cell Transient Overexpression Lysate(Denatured)

DHCR7 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

5 Item(s)

per page
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