AADAT antibody

Principal name

AADAT antibody

Alternative names for AADAT antibody

KAT2, Kynurenine aminotransferase II, Kynurenine-oxoglutarate aminotransferase II, Kynurenine-oxoglutarate transaminase II, 2-aminoadipate transaminase, 2-aminoadipate aminotransferase, Alpha-aminoadipate aminotransferase

SwissProt ID

Q64602 (Rat), Q8N5Z0 (Human), Q9WVM8 (Mouse)

Gene ID

51166 (AADAT), 23923 (Aadat), 29416

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Rt (Rat), Mky (Monkey), Eq (Equine), Por (Porcine), Rb (Rabbit), Ze (Zebrafish), GP (Guinea Pig), Ye (Yeast)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunoprecipitation (IP)

Background of AADAT antibody

AADAT is a protein that is highly similar to mouse and rat kynurenine aminotransferase II. The rat protein is a homodimer with two transaminase activities. One activity is the transamination of alpha-aminoadipic acid, a final step in the saccaropine pathway which is the major pathway for L-lysine catabolism. The other activity involves the transamination of kynurenine to produce kynurenine acid, the precursor of kynurenic acid which has neuroprotective properties.This gene encodes a protein that is highly similar to mouse and rat kynurenine aminotransferase II. The rat protein is a homodimer with two transaminase activities. One activity is the transamination of alpha-aminoadipic acid, a final step in the saccaropine pathway which is the major pathway for L-lysine catabolism. The other activity involves the transamination of kynurenine to produce kynurenine acid, the precursor of kynurenic acid which has neuroprotective properties. Two alternative transcripts encoding the same isoform have been identified, however, additional alternative transcripts and isoforms may exist.

General readings

Goh DL, Patel A, Thomas GH, Salomons GS, Schor DS, Jakobs C, Geraghty MT.
Characterization of the human gene encoding alpha-aminoadipate aminotransferase (AADAT).
Mol Genet Metab. 2002 Jul;76(3):172-80.
PMID: 12126930

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

AADAT antibody

  Goat Polyclonal Antibody against AADAT  
TA303317 (1µg/ml) staining of Human Liver lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

AADAT antibody

  Rabbit anti-AADAT polyclonal antibody  
Western blot analysis of THP1 cells (Lanes 1 and 2: 60ug lysate) and Jurkat cells (Lane 3: 80ug lysate) with anti-AADAT antibody diluated at 1:2000. (Predicted and observed size: 47kDa) Rabbit IgG Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

AADAT antibody

  KATII / AADAT Rabbit Polyclonal (N-Terminus) Antibody  
Anti-AADAT antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu P
50 µg / €400.00
  OriGene Technologies, Inc.

AADAT antibody

  KATII / AADAT Rabbit Polyclonal (Internal) Antibody  
Anti-AADAT antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit IgG Purified Hu, Mky P
50 µg / €400.00
  OriGene Technologies, Inc.

AADAT antibody

  KATII / AADAT Rabbit Polyclonal (Internal) Antibody  
Anti-AADAT antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu P
50 µg / €400.00
  OriGene Technologies, Inc.

AADAT antibody

  Rabbit Polyclonal Anti-AADAT Antibody  
WB Suggested Anti-AADAT Antibody Titration: 1.25ug/ml; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Por, Rb, Rt, Ze P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

AADAT antibody

  Rabbit Polyclonal Anti-AADAT Antibody  
WB Suggested Anti-AADAT Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: COLO205 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ye, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

AADAT (Center) antibody

AADAT Antibody (Center) (Cat. #AP50010PU-N) western blot analysis in HepG2,Y79 cell line lysates (35ug/lane).This demonstrates the AADAT antibody detected the AADAT protein (arrow) Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

Aadat - mouse gene knockout kit via CRISPR

Aadat - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Aadat - mouse gene knockout kit via CRISPR

Aadat - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Aadat - mouse gene knockout kit via CRISPR

Aadat - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Aadat - mouse gene knockout kit via CRISPR

Aadat - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

AADAT (transcript variant 2)

  Recombinant protein of human aminoadipate aminotransferase (AADAT), transcript variant 2  
AADAT Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

AADAT (transcript variant 1)

  Recombinant protein of human aminoadipate aminotransferase (AADAT), transcript variant 1  
AADAT Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, AADAT (mGFP-tagged) - Human aminoadipate aminotransferase (AADAT), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, AADAT (mGFP-tagged) - Human aminoadipate aminotransferase (AADAT), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,020.00
  OriGene Technologies, Inc.

Lenti ORF particles, AADAT (mGFP-tagged) - Human aminoadipate aminotransferase (AADAT), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, AADAT (mGFP-tagged) - Human aminoadipate aminotransferase (AADAT), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,020.00
  OriGene Technologies, Inc.

Lenti ORF particles, AADAT (Myc-DDK tagged) - Human aminoadipate aminotransferase (AADAT), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, AADAT (Myc-DDK tagged) - Human aminoadipate aminotransferase (AADAT), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €910.00
  OriGene Technologies, Inc.

Lenti ORF particles, AADAT (Myc-DDK tagged) - Human aminoadipate aminotransferase (AADAT), transcript variant 2 , 200 uL, >10^7 TU/mL

Lenti ORF particles, AADAT (Myc-DDK tagged) - Human aminoadipate aminotransferase (AADAT), transcript variant 2 , 200 uL, >10^7 TU/mL  
200 µl / €910.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Aadat (GFP-tagged) - Mouse aminoadipate aminotransferase (Aadat), 200 uL, >10^7 TU/mL

Lenti ORF particles, Aadat (GFP-tagged) - Mouse aminoadipate aminotransferase (Aadat), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Aadat (Myc-DDK-tagged) - Mouse aminoadipate aminotransferase (Aadat), 200 uL, >10^7 TU/mL

Lenti ORF particles, Aadat (Myc-DDK-tagged) - Mouse aminoadipate aminotransferase (Aadat), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

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