AADC / DDC antibody

Principal name

AADC / DDC antibody

Alternative names for AADC / DDC antibody

DOPA decarboxylase, Aromatic-L-amino-acid decarboxylase

SwissProt ID

O88533 (Mouse), P14173 (Rat), P20711 (Human), P27718 (Bovin), P80041 (Pig)

Gene ID

1644 (DDC), 280762, 24311 (Ddc)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), GP (Guinea Pig), Rb (Rabbit), Sh (Sheep), Por (Porcine), Ze (Zebrafish), African clawed frog, Xen (Xenopus), Eq (Equine)

Available hosts

Rabbit, Sheep, Goat, Mouse

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Paraffin Sections (P), Western blot / Immunoblot (WB), Frozen Sections (C), EPair for Elisa (EPair), ELISA (detection) (E(detection))

Background of AADC / DDC antibody

DOPA decarboxylase is an enzyme implicated in 2 metabolic pathways, synthesizing 2 important neurotransmitters: dopamine and serotonin which both play key roles in many clinical disorders, including Parkinson's disease. Following the hydroxylation of tyrosine to form L dihydroxyphenylalanine (LDOPA), catalyzed by tyrosine hydroxylase, DDC decarboxylates LDOPA to form dopamine. This neurotransmitter is found in different areas of the brain and is particularly abundant in basal ganglia. Dopamine is also produced by DDC in the sympathetic nervous system and is the precursor of the catecholaminergic hormones, noradrenaline and adrenaline in the adrenal medulla. In the nervous system, tryptophan hydroxylase produces 5 OH tryptophan, which is decarboxylated by DDC, giving rise to serotonin. DDC is a homodimeric, pyridoxal phosphate dependent enzyme.

General readings

Voeller KK. Attention-deficit hyperactivity disorder (ADHD). J Child Neurol. 2004 Oct;19(10):798-814. Review.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

AADC / DDC antibody

Western blot of rat adrenal medulla.  As shown in the autoradiograph, the antibody is specific for the ~55k DDC protein. Rabbit IgG Aff - Purified Bov, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

AADC / DDC (N-term) antibody

Western blot of 5 μg of bovine adrenal medulla lysate showing specific immunolabeling of the ~55k DOPA decarboxylase protein. Rabbit IgG Aff - Purified Bov, Can, GP, Hu, Rb, Rt, Sh WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

AADC / DDC antibody

TA302469 (0.03µg/ml) staining of Human Kidney lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

AADC / DDC antibody

Western blot analysis of DDC in human lung tissue lysate with DDC antibody at 1 ug/ml. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

AADC / DDC antibody

WB Suggested Anti-DDC Antibody Titration: 5.0 ug/ml; Positive Control: HepG2 cell lysateDDC is supported by BioGPS gene expression data to be expressed in HepG2 Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Ze P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

AADC / DDC antibody

WB Suggested Anti-DDC Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: Human Spleen Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

AADC / DDC antibody

AADC / DDC Rabbit IgG Purified Bov, Rt WB
0.1 ml / €500.00
  Acris Antibodies GmbH

AADC / DDC antibody

Western Blot analysis of DDC expression in transfected 293T cell line (H00001644-T01) by DDC MaxPab polyclonal antibody.

Lane 1: DDC transfected lysate(52.8 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

AADC / DDC antibody

Western Blot analysis of DDC expression in transfected 293T cell line (H00001644-T01) by DDC MaxPab polyclonal antibody.

Lane 1: DDC transfected lysate(52.8 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

AADC / DDC antibody

Western Blot analysis of DDC expression in transfected 293T cell line (H00001644-T02) by DDC MaxPab polyclonal antibody.

Lane 1: DDC transfected lysate(52.8 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

AADC / DDC antibody

Western Blot analysis of DDC expression in transfected 293T cell line (H00001644-T04) by DDC MaxPab polyclonal antibody.

Lane 1: DDC transfected lysate(53.90 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu, Ms E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

AADC / DDC antibody

AADC / DDC Mouse IgG2a 8E8 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

AADC / DDC antibody

DDC polyclonal antibody ( Cat # PAB6783 ) ( 0.03 µg/ml ) staining of human kidney lysate ( 35 µg protein in RIPA buffer ) . Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

AADC / DDC antibody

Western blot of 5 µg of bovine adrenal medulla lysate showing specific immunolabeling of the ~55k DDC protein. Using DDC polyclonal antibody ( Cat # PAB9598 ). Rabbit Bov, GP, Hu, Rb, Rt, Sh WB
0.1 ml / €470.00
  Abnova Taiwan Corp.

AADC / DDC antibody

AADC / DDC Rabbit Bov, Rt WB
0.1 ml / €470.00
  Abnova Taiwan Corp.

AADC / DDC antibody

Human Kidney; Rabbit Anti-DDC Antibody. Catalog Number: ARP41425. Paraffin Embedded Tissue: Human Kidney. Cellular Data: Epithelial cells of renal tubule. Antibody Concentration: 4.0-8.0 ug/ml. Magnification: 400X; DDC antibody - N-terminal region (ARP41425_T100) in Human Kidney cells using Immunohistochemistry Rabbit Aff - Purified African clawed frog, Bov, Can, Hu, Ms, Por, Rt, Ze P, WB
0.1 mg / €310.00
  AVIVA Systems Biology

AADC / DDC antibody

Human Spleen; WB Suggested Anti-DDC Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: Human Spleen; DDC antibody - middle region (ARP41426_P050) in Human Spleen cells using Western Blot Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

AADC / DDC antibody

AADC / DDC Mouse IgG2b 413911 Purified Hu, Rt C, E, WB
0.1 mg / €340.00
  Neuromics Antibodies

AADC / DDC antibody

Western Blot: DOPA decarboxylase Antibody [NB100-1785] - NB100-1785 (0.03ug/ml) staining of Human Kidney lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat IgG Aff - Purified Hu E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

AADC / DDC antibody

AADC / DDC Rabbit Purified Rt WB
0.1 ml / €380.00
  Novus Biologicals Inc.

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