AARS antibody

Principal name

AARS antibody

Alternative names for AARS antibody

Alanine-tRNA ligase, Renal carcinoma antigen NY-REN-42

SwissProt ID

P49588 (Human), P50475 (Rat), Q8BGQ7 (Mouse)

Gene ID

16 (AARS)

Available reactivities

Hu (Human), Bov (Bovine), Chk (Chicken), Ms (Mouse), Rt (Rat), Ze (Zebrafish), African clawed frog

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP)

Background of AARS antibody

The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases, of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41% identity witht the E.coli protein. tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure. The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases, of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41% identity witht the E.coli protein. tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure.

General readings

Olsen,J.V., (2006) Cell 127 (3), 635-648

2 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

AARS (N-term) antibody

Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with AARS antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Purified Hu P, WB
0.4 ml / €360.00
  Acris Antibodies GmbH

AARS N-term antibody

Sample (30 ug of whole cell lysate)  A: 293T   B: A431   C: HepG2   7.5% SDS PAGE  GTX112386 diluted at 1:1000 Rabbit IgG Aff - Purified Hu P, WB

Regular Price: 0.1 ml / €350.00

Special Price: 0.1 ml / €297.50

  GeneTex Inc.

2 Item(s)

per page
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