AATF antibody

Principal name

AATF antibody

Alternative names for AATF antibody

CHE1, DED, HSPC277, CHE-1, Apoptosis-antagonizing transcription factor, Rb-binding protein Che-1

SwissProt ID

Q9JKX4 (Mouse), Q9NY61 (Human), Q9QYW0 (Rat)

Gene ID

26574 (AATF), 56321 (Aatf), 114512

Available reactivities

Can (Canine), Hu (Human), Rt (Rat), Bov (Bovine), Chk (Chicken), Ms (Mouse), African clawed frog, Mky (Monkey), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Ye (Yeast), Ze (Zebrafish)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP)

Background of AATF antibody

AATF (apoptosis antagonizing transcription factor) was initially discovered as an interaction partner of ZIP kinase (ZIPK) (1), a member of death-associated protein (DAP) kinase family of pro-apoptotic serine/threonine kinases (2). AATF is a phosphoprotein containing an acidic region and a putative leucine zipper domain and nuclear localization signal, features which are typical of transcription factors. AATF inhibits the ZIPK-mediated pro-apoptotic pathway and may activate other anti-apoptotic pathways (3). Recently, it has also been shown to protect neural cells against oxidative damage induced by amyloid b-peptide and to inhibit aberrant production of the b-peptide by interacting with Par-4 (prostate apoptosis response-4), another pro-apoptotic leucine zipper protein that is associated with neuronal degeneration in Alzheimer’s disease (AD) (4,5), suggesting that AATF may have potential therapeutic applications in both familial and sporadic forms of AD.

General readings

Burgdorf,S., et al., (2004) J. Biol. Chem. 279 (17), 17524-17534

17 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

AATF antibody

  Rabbit Polyclonal AATF Antibody  
Western blot analysis of AATF in human small intestine cell lysate with AATF antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml. Rabbit IgG Aff - Purified Hu, Ms E, ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

AATF antibody

  Rabbit polyclonal anti-AATF antibody  
Western blot analysis of extracts from HeLa cells, HepG2 cells, COLO205 cells and HUVEC cells, using AATF antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

AATF antibody

  Rabbit Polyclonal anti-AATF antibody  
WB Suggested Anti-AATF Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:12500; Positive Control: Human kidney Rabbit IgG Purified Hu P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

AATF antibody

  Rabbit Polyclonal Anti-AATF Antibody  
WB Suggested Anti-AATF Antibody Titration: 5.0 ug/ml; ELISA Titer: 1: 312500; Positive Control: Daudi cell lysate. AATF is supported by BioGPS gene expression data to be expressed in Daudi Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

AATF antibody

  Rabbit Polyclonal Anti-AATF Antibody  
WB Suggested Anti-AATF Antibody Titration: 0.25 ug/ml; ELISA Titer: 1: 312500; Positive Control: Human kidney Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ye, Ze WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

AATF antibody

  Rabbit Polyclonal Anti-AATF Antibody  
Gel: 6%SDS-PAGE, Lysate: 40 ug, Lane 1-2: Mouse heart tissue, 231 cells, Primary antibody: (AATF Antibody) at dilution 1/667, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

AATF antibody

Figure 1. Formalin-Fixed Paraffin-Embedded (FFPE) on Testis. Rabbit Purified Hu, Ms P, WB
50 µg / €470.00
  Acris Antibodies GmbH

AATF antibody

Western blot analysis of extracts from HeLa cells/HepG2 cells/COLO205 cells/HuvEc cells, using AATF Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
50 µg / €230.00
  Assay Biotech

AATF antibody

Western blot analysis of extracts from HeLa cells/HepG2 cells/COLO205 cells/HuvEc cells, using AATF Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

AATF - human gene knockout kit via CRISPR

AATF - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

AATF - human gene knockout kit via CRISPR

AATF - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

AATF - human gene knockout kit via CRISPR

AATF - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Aatf - mouse gene knockout kit via CRISPR

Aatf - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

AATF (full length, C-term DDK tag)

  Purified recombinant protein of Human apoptosis antagonizing transcription factor (AATF), full length, with C-terminal DDK tag, expressed in sf9, 20ug  
AATF Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
SF9 cells
20 µg / €399.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Aatf (GFP-tagged) - Mouse apoptosis antagonizing transcription factor (Aatf), 200 uL, >10^7 TU/mL

Lenti ORF particles, Aatf (GFP-tagged) - Mouse apoptosis antagonizing transcription factor (Aatf), 200 uL, >10^7 TU/mL  
200 µl / €1,150.00
  OriGene Technologies, Inc.

Lenti ORF particles, Aatf (Myc-DDK-tagged) - Mouse apoptosis antagonizing transcription factor (Aatf), 200 uL, >10^7 TU/mL

Lenti ORF particles, Aatf (Myc-DDK-tagged) - Mouse apoptosis antagonizing transcription factor (Aatf), 200 uL, >10^7 TU/mL  
200 µl / €1,030.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Aatf (Myc-DDK-tagged ORF) - Rat apoptosis antagonizing transcription factor (Aatf), 200 uL, >10^7 TU/mL

Lenti ORF particles, Aatf (Myc-DDK-tagged ORF) - Rat apoptosis antagonizing transcription factor (Aatf), 200 uL, >10^7 TU/mL  
200 µl / €1,029.00
  OriGene Technologies, Inc.

17 Item(s)

per page
  • LinkedIn