ABCA4 antibody

Principal name

ABCA4 antibody

Alternative names for ABCA4 antibody

ABCR, Stargardt disease protein, ATP-binding cassette sub-family A member 4, Retinal-specific ATP-binding cassette transporter

SwissProt ID

O35600 (Mouse), P78363 (Human)

Gene ID

24 (ABCA4), 11304 (Abca4)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Xen (Xenopus)

Available hosts

Mouse, Goat, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Frozen Sections (C), Paraffin Sections (P)

Background of ABCA4 antibody

ABCA4 (ATP-binding cassette, sub-family A (ABC1), member 4, Rim Protein) is a member of the superfamily of ATP-binding cassette (ABC) transporters (Illing et al., 1997). ABC proteins transport various molecules across extra- and intracellular membranes. This protein is a retina-specific ABC transporter with N-retinylidene-PE as a substrate. It is expressed exclusively in retina photoreceptor cells, indicating the gene product mediates transport of an essential molecule across the photoreceptor cell membrane. Mutations in this gene are found in patients diagnosed with Stargardt disease and are associated with retinitis pigmentosa-19 and age-related macular degeneration (Wiszniewski et al., 2003). Defects in ABCA4 are the cause of Stargardt disease type 1 (STGD1) (Molday et al., 2000). STGD is one of the most frequent causes of macular degeneration in childhood. Defects in ABCA4 are also known to cause fundus flavimaculatus (FFM), age-related macular degeneration type 2 (ARMD2) and cone-rod dystrophy type 3 (CORD3) (Klevering et al., 2005).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ABCA4 antibody

  Mouse Anti-ABCA4 (Rim Protein) Antibody  
Immunohistochemical staining of adult mouse retina showing specific immunolabeling of  the ABCA4 protein.  Photo courtesy of Mary Raven, University of California, Santa Barbara, CA. Mouse IgG 3F4 Purified Bov, Hu, Ms, Xen C, WB
0.1 ml / €383.00
  OriGene Technologies, Inc.

ABCA4 antibody

  Anti-ABCA4 Rabbit Polyclonal Antibody  
Predicted cell location: Membrane,Cytoplasm. Positive control: Human cerical and thyroid cancer tissue. Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded human cervical cancer tissue using ABCA4 antibody at dilution 1/30, on the right is treated with the synthetic peptide. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €335.00
  OriGene Technologies, Inc.


Catalog No. Species Donor Vector  

ABCA4 - human gene knockout kit via CRISPR

ABCA4 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

3 Item(s)

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