ABCB2 / APT1 / TAP1 antibody

Principal name

ABCB2 / APT1 / TAP1 antibody

Alternative names for ABCB2 / APT1 / TAP1 antibody

PSF1, RING4, Y3, Antigen peptide transporter 1, ATP-binding cassette sub-family B member 2, Peptide supply factor 1, Peptide transporter PSF1, Peptide transporter involved in antigen processing 1

SwissProt ID

P21958 (Mouse), P36370 (Rat), Q03518 (Human)

Gene ID

6890 (TAP1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Mky (Monkey), Bov (Bovine), Chk (Chicken), African clawed frog, Xen (Xenopus), Eq (Equine), GP (Guinea Pig), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Rabbit, Mouse, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Paraffin Sections (P), Flow Cytometry (F)

Background of ABCB2 / APT1 / TAP1 antibody

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). TAP1 is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. TAP1 is involved in the pumping of degraded cytosolic peptides across the endoplasmic reticulum into the membrane-bound compartment where class I molecules assemble.The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is involved in the pumping of degraded cytosolic peptides across the endoplasmic reticulum into the membrane-bound compartment where class I molecules assemble. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

1. Nijenhuis, M., et al., J. Immunol. 157, 5467-5477 (1996)
2. Nijenhuis, M., et al., J. Immunol. 156, 2186-2195 (1996)
Clone TAP1.28 is used in reference 2.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ABCB2 / APT1 / TAP1 antibody

(1ug/ml) staining of MCF7 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ABCB2 / APT1 / TAP1 antibody

WB Suggested Anti-TAP1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: MCF7 cell lysate Rabbit IgG Purified Bov, Eq, GP, Hu, Ms, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

ABCB2 / APT1 / TAP1 (507-748) antibody

Western blot anaylsis: AM20194AF-N TAP1 antibody staining of LCL721 cells. Mouse IgG1 TAP1.28 Azide Free Hu F, IP, WB
0.1 mg / €310.00
  Acris Antibodies GmbH

ABCB2 / APT1 / TAP1 (507-748) antibody

Flow Cytometry: Analysis of TAP1 expression on LCL721 (Left) and Jurkat (Right). Open histogram indicates the reaction of isotypic control to the cells. Shaded histogram indicates the reaction of TAP1 antibody AM20194FC-N to the cells. Mouse IgG1 TAP1.28 FITC Hu F
50 µg / €340.00
  Acris Antibodies GmbH

ABCB2 / APT1 / TAP1 (C-term) antibody

ABCB2 / APT1 / TAP1 Rabbit IgG Purified Hu E, F, IP, WB
50 µg / €300.00
  Acris Antibodies GmbH

ABCB2 / APT1 / TAP1 (C-term) antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

ABCB2 / APT1 / TAP1 antibody

ABCB2 / APT1 / TAP1 Rabbit Ig Fraction Hu E, WB
0.1 mg / €440.00
  Acris Antibodies GmbH

ABCB2 / APT1 / TAP1 antibody

Western Blot analysis of TAP1 expression in transfected 293T cell line by TAP1 monoclonal antibody (M01), clone 2B4.

Lane 1: TAP1 transfected lysate(80.965 KDa).
Lane 2: Non-transfected lysate. Mouse IgG3 2B4 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

ABCB2 / APT1 / TAP1 antibody

Detection limit for recombinant GST tagged TAP1 is approximately 1ng/ml as a capture antibody. Mouse IgG3 1B11 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

ABCB2 / APT1 / TAP1 antibody

Western Blot analysis of TAP1 expression in transfected 293T cell line by TAP1 monoclonal antibody (M03), clone 3D10.

Lane 1: TAP1 transfected lysate(87.2 KDa).
Lane 2: Non-transfected lysate. Mouse IgG3 3D10 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

ABCB2 / APT1 / TAP1 antibody

Western Blot detection against Immunogen (37.73 KDa) . Mouse IgG3 3D4 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

ABCB2 / APT1 / TAP1 antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with TAP1 polyclonal antibody ( Cat # PAB4832 ) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma. Rabbit Hu E, P
0.4 ml / €390.00
  Abnova Taiwan Corp.

ABCB2 / APT1 / TAP1 antibody

ABCB2 / APT1 / TAP1 Hu
0.1 mg / €560.00
  Abnova Taiwan Corp.

ABCB2 / APT1 / TAP1 antibody

Human Lung Tissue; Rabbit Anti-TAP1 Antibody . Catalog Number: ARP43628_P050 . Formalin Fixed Paraffin Embedded Tissue: Human Lung Tissue . Observed Staining: Cytoplasmic in alveolar type I & II cells . Primary Antibody Concentration: 1:100 . Secondary Antibody: Donkey anti-Rabbit-Cy3 . Secondary Antibody Concentration: 1:200 . Magnification: 20X . Exposure Time: 0.5 - 2.0 sec .; Rabbit Anti-TAP1 Antibody (ARP43628_P050) ) in Human Lung Tissue using Immunohistochemistry Rabbit Aff - Purified African clawed frog, Bov, Chk, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

ABCB2 / APT1 / TAP1 antibody

TAP1 Antibody [53H8] Mouse IgG1 53H8 Purified Hu E, ICC/IF, IP, WB
0.1 ml / €400.00
  Immuquest

ABCB2 / APT1 / TAP1 antibody

TAP1 Antibody [53H8] Mouse IgG1 53H8 Purified Hu E, ICC/IF, IP, WB
50 µl / €360.00
  Immuquest

ABCB2 / APT1 / TAP1 antibody

ABCB2 / APT1 / TAP1 Mouse IgG1 TAP1.28 Purified Hu F, IP, WB
50 µg / €320.00
  Novus Biologicals Inc.

ABCB2 / APT1 / TAP1 antibody

Western Blot: TAP1 Antibody [NBP1-59030] - This Anti-TAP1 antibody was used in Western Blot of MCF7 tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Bov, Chk, Hu, Ms, Rt, Xen WB
50 µg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

ABCB2 / APT1 / TAP1

ABCB2 / APT1 / TAP1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

ABCB2 / APT1 / TAP1

ABCB2 / APT1 / TAP1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

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