ABCC5 / MRP5 antibody

Principal name

ABCC5 / MRP5 antibody

Alternative names for ABCC5 / MRP5 antibody

Multidrug resistance-associated protein 5, pABC11, SMRP, MOAT-C, ATP-binding cassette sub-family C member 5, Multi-specific organic anion transporter C

SwissProt ID

O15440 (Human), Q9QYM0 (Rat), Q9R1X5 (Mouse)

Gene ID

10057 (ABCC5), 27416 (Abcc5)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Eq (Equine), Hst (Hamster), Mky (Monkey), Ms (Mouse), Por (Porcine), Prim (Primate), Rb (Rabbit), Rt (Rat), Tr (Turkey), Bear

Available hosts

Goat, Mouse, Rat, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C)

Background of ABCC5 / MRP5 antibody

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions in the cellular export of its substrate, cyclic nucleotides. This export contributes to the degradation of phosphodiesterases and possibly an elimition pathway for cyclic nucleotides. Studies show that this protein provides resistance to thiopurine anticancer drugs, 6-mercatopurine and thioguanine, and the anti-HIV drug 9-(2-phosphonylmethoxyethyl)adenine. This protein may be involved in resistance to thiopurines in acute lymphoblastic leukemia and antiretroviral nucleoside alogs in HIV-infected patients. Altertive splicing of this gene has been detected; however, the complete sequence and translation initiation site is unclear. [provided by RefSeq, Jul 2008].

General readings

1. Kool et al. Analysis of expression of cMOAT (MRP2), MRP3, MRP4 and MRP5, homologs of the multidrug resistance associated protein gene (MRP1), in human cancer cell lines
Cancer res. 57: 3537-3547, 1997
2. Scheffer et al. Specific detection of multidrug resistance proteins MRP1, MPR2, MRP3, MRP5 and MDR3 p-Glycoprotein with a panel of monoclonal antibodies. Cancer Research, 60, 5269-77, 2000.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ABCC5 / MRP5 antibody

  ABCC5 mouse monoclonal antibody, clone OTI2C8 (formerly 2C8)  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-ABCC5 mouse monoclonal antibody.(Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3 min, TA808487)(1:150) Mouse IgG1 OTI2C8 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

ABCC5 / MRP5 (N-term) antibody

  Goat Polyclonal Antibody against ABCC5  
TA303365 (0.5µg/ml) staining of Human Frontal Cortex lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ABCC5 / MRP5 antibody

  Anti-ABCC5 Rabbit Polyclonal Antibody  
Predicted band size: 161 kDa . Positive control: Mouse heart tissue lysate. Recommended dilution: 1/1000-5000. (Gel: 10%SDS-PAGE Lysate: 40 ug per lane Primary antibody: 1/950 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 10 minutes) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

ABCC5 / MRP5 antibody

  Anti-ABCC5 Rabbit Polyclonal Antibody  
Western blot analysis of Mouse eyes tissue using TA322564 (ABCC5 Antibody) at dilution 1/1150 Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

ABCC5 / MRP5 antibody

  ABCC5 mouse monoclonal antibody, clone OTI5A8 (formerly 5A8)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ABCC5 (RC217669, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ABCC5.(1:2000) Mouse IgG1 OTI5A8 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

ABCC5 / MRP5 antibody

  ABCC5 mouse monoclonal antibody, clone OTI5F4 (formerly 5F4)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ABCC5 (RC217669, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ABCC5.(1:2000) Mouse IgG1 OTI5F4 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

ABCC5 / MRP5 antibody

  ABCC5 mouse monoclonal antibody, clone OTI1F3 (formerly 1F3)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ABCC5 (RC217669, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ABCC5.(1:2000) Mouse IgG2b OTI1F3 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

ABCC5 / MRP5 antibody

  ABCC5 mouse monoclonal antibody, clone OTI4B1 (formerly 4B1)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ABCC5 (RC217669, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ABCC5.(1:2000) Mouse IgG1 OTI4B1 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

ABCC5 / MRP5 antibody

  ABCC5 mouse monoclonal antibody, clone OTI6C6 (formerly 6C6)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ABCC5 (RC217669, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ABCC5.(1:2000) Mouse IgG1 OTI6C6 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

ABCC5 / MRP5 antibody

ABCC5 / MRP5 Rat IgG2a M5I-10 Supernatant Hu C, ICC/IF, WB
1 ml / €420.00
  Acris Antibodies GmbH

ABCC5 / MRP5 antibody

ABCC5 / MRP5 Rat IgG2a M5II-54 Supernatant Hu C, ICC/IF, WB
1 ml / €420.00
  Acris Antibodies GmbH

ABCC5 / MRP5 antibody

ABCC5 / MRP5 Rat IgG2a M5I-1 Supernatant Hu C, ICC/IF, WB
1 ml / €420.00
  Acris Antibodies GmbH

ABCC5 / MRP5 (2-13) antibody

Liver: Formalin-Fixed Paraffin-Embedded (FFPE) Goat IgG Aff - Purified Bear, Bov, Can, Chk, Eq, Hst, Hu, Mky, Ms, Por, Prim, Rb, Rt, Tr E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

ABCC5 - human gene knockout kit via CRISPR

ABCC5 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

ABCC5 - human gene knockout kit via CRISPR

ABCC5 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

ABCC5 - human gene knockout kit via CRISPR

ABCC5 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

ABCC5 - human gene knockout kit via CRISPR

ABCC5 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

ABCC5 overexpression lysate

ABCC5 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, ABCC5 (mGFP-tagged) - Human ATP-binding cassette, sub-family C (CFTR/MRP), member 5 (ABCC5), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, ABCC5 (mGFP-tagged) - Human ATP-binding cassette, sub-family C (CFTR/MRP), member 5 (ABCC5), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, ABCC5 (Myc-DDK tagged) - Human ATP-binding cassette, sub-family C (CFTR/MRP), member 5 (ABCC5), transcript variant 2 , 200 uL, >10^7 TU/mL

Lenti ORF particles, ABCC5 (Myc-DDK tagged) - Human ATP-binding cassette, sub-family C (CFTR/MRP), member 5 (ABCC5), transcript variant 2 , 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

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