ABCC5 / MRP5 antibody

Principal name

ABCC5 / MRP5 antibody

Alternative names for ABCC5 / MRP5 antibody

Multidrug resistance-associated protein 5, pABC11, SMRP, MOAT-C, ATP-binding cassette sub-family C member 5, Multi-specific organic anion transporter C

SwissProt ID

O15440 (Human), Q9QYM0 (Rat), Q9R1X5 (Mouse)

Gene ID

10057 (ABCC5)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Ms (Mouse), Rt (Rat), Chk (Chicken), Por (Porcine)

Available hosts

Goat, Mouse, Rat, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of ABCC5 / MRP5 antibody

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions in the cellular export of its substrate, cyclic nucleotides. This export contributes to the degradation of phosphodiesterases and possibly an elimition pathway for cyclic nucleotides. Studies show that this protein provides resistance to thiopurine anticancer drugs, 6-mercatopurine and thioguanine, and the anti-HIV drug 9-(2-phosphonylmethoxyethyl)adenine. This protein may be involved in resistance to thiopurines in acute lymphoblastic leukemia and antiretroviral nucleoside alogs in HIV-infected patients. Altertive splicing of this gene has been detected; however, the complete sequence and translation initiation site is unclear. [provided by RefSeq, Jul 2008].

General readings

1. Kool et al. Analysis of expression of cMOAT (MRP2), MRP3, MRP4 and MRP5, homologs of the multidrug resistance associated protein gene (MRP1), in human cancer cell lines
Cancer res. 57: 3537-3547, 1997
2. Scheffer et al. Specific detection of multidrug resistance proteins MRP1, MPR2, MRP3, MRP5 and MDR3 p-Glycoprotein with a panel of monoclonal antibodies. Cancer Research, 60, 5269-77, 2000.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ABCC5 / MRP5 antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-ABCC5 mouse monoclonal antibody.(Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3 min, TA808487)(1:150) Mouse IgG1 OTI2C8 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

ABCC5 / MRP5 (N-term) antibody

TA303365 (0.5µg/ml) staining of Human Frontal Cortex lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ABCC5 / MRP5 antibody

Predicted band size: 161 kDa . Positive control: Mouse heart tissue lysate. Recommended dilution: 1/1000-5000. (Gel: 10%SDS-PAGE Lysate: 40 ug per lane Primary antibody: 1/950 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 10 minutes) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

ABCC5 / MRP5 antibody

Western blot analysis of Mouse eyes tissue using TA322564 (ABCC5 Antibody) at dilution 1/1150 Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

ABCC5 / MRP5 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ABCC5 (RC217669, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ABCC5.(1:2000) Mouse IgG1 OTI5A8 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

ABCC5 / MRP5 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ABCC5 (RC217669, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ABCC5.(1:2000) Mouse IgG1 OTI5F4 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

ABCC5 / MRP5 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ABCC5 (RC217669, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ABCC5.(1:2000) Mouse IgG2b OTI1F3 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

ABCC5 / MRP5 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ABCC5 (RC217669, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ABCC5.(1:2000) Mouse IgG1 OTI4B1 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

ABCC5 / MRP5 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ABCC5 (RC217669, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ABCC5.(1:2000) Mouse IgG1 OTI6C6 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

ABCC5 / MRP5 antibody

ABCC5 / MRP5 Rat IgG2a M5I-10 Supernatant Hu C, ICC/IF, WB
1 ml / €420.00
  Acris Antibodies GmbH

ABCC5 / MRP5 antibody

ABCC5 / MRP5 Rat IgG2a M5II-54 Supernatant Hu C, ICC/IF, WB
1 ml / €420.00
  Acris Antibodies GmbH

ABCC5 / MRP5 antibody

ABCC5 / MRP5 Rat IgG2a M5I-1 Supernatant Hu C, ICC/IF, WB
1 ml / €420.00
  Acris Antibodies GmbH

ABCC5 / MRP5 (2-13) antibody

Liver: Formalin-Fixed Paraffin-Embedded (FFPE) Goat IgG Aff - Purified Bear, Bov, Can, Chk, Eq, Hst, Hu, Mky, Ms, Por, Prim, Rb, Rt, Tr E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

ABCC5 / MRP5 antibody

ABCC5 / MRP5 Mouse IgG2a 1B12 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

ABCC5 / MRP5 antibody

ABCC5 polyclonal antibody ( Cat # PAB7484 ) ( 0.5 µg/ml ) staining of human frontal cortex lysate ( 35 µg protein in RIPA buffer ) . Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

ABCC5 / MRP5 antibody

Western Blot: MRP5 Antibody [NB100-94881]- (0.5ug/ml) staining of Human Frontal Cortex lysate (35ug protein in RIPA buffer). Goat IgG Aff - Purified Bov, Chk, Hu, Ms, Rt E, P, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

ABCC5 / MRP5 antibody

ABCC5 / MRP5 Rat IgG2a M5II-54 Hu C, P, WB
0.2 ml / €290.00
  Novus Biologicals Inc.

ABCC5 / MRP5 antibody

ABCC5 / MRP5 Rat IgG2a M51-1 Hu C, F, P, WB
0.2 ml / €290.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

ABCC5 / MRP5

ABCC5 / MRP5 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

ABCC5 / MRP5

ABCC5 / MRP5 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

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