ABCD2 / ALDR antibody

Principal name

ABCD2 / ALDR antibody

Alternative names for ABCD2 / ALDR antibody

Adrenoleukodystrophy-related protein, Adrenoleukodystrophy-like 1, ALD1, ALDL1, ALDRP, ATP-binding cassette sub-family D member 2

SwissProt ID

Q61285 (Mouse), Q9QY44 (Rat), Q9UBJ2 (Human)

Gene ID

225 (ABCD2), 26874 (Abcd2), 84356

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Ze (Zebrafish), Ye (Yeast)

Available hosts

Rabbit, Goat

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of ABCD2 / ALDR antibody

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functiol homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown; however this protein is speculated to function as a dimerization partner of ABCD1 and/or other peroxisomal ABC transporters. Mutations in this gene have been observed in patients with adrenoleukodystrophy, a severe demyeliting disease. This gene has been identified as a candidate for a modifier gene, accounting for the extreme variation among adrenoleukodystrophy phenotypes. This gene is also a candidate for a complement group of Zellweger syndrome, a genetically heterogeneous disorder of peroxisomal biogenesis. [provided by RefSeq, Jul 2008].

General readings

Saito, A., et al. J. Hum. Genet. 54(6):317-323(2009) Maier, E.M., et al. Biochem. Biophys. Res. Commun. 377(1):176-180(2008) Lu, Y., et al. J. Lipid Res. 49(12):2582-2589(2008)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ABCD2 / ALDR antibody

  Rabbit polyclonal antibody to ABCD2 (ATP-binding cassette, sub-family D (ALD), member 2)  
Sample (30 ug of whole cell lysate). A: A431 . 7.5% SDS PAGE. TA308846 diluted at 1:1000. Rabbit IgG Aff - Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

ABCD2 / ALDR (460-473) antibody

  Goat Anti-ABCD2 (aa460-473) Antibody  
(1ug/ml) staining of Human Liver lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ABCD2 / ALDR antibody

  Anti-ABCD2 Rabbit Polyclonal Antibody  
Predicted cell location: Cytoplasm . Positive control: Human ovarian and thyroid cancer tissue . Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded human ovarian cancer tissue using ABCD2 antibody at dilution 1/20, on the right is treated with the synthetic peptide. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt P
0.1 ml / €325.00
  OriGene Technologies, Inc.

ABCD2 / ALDR antibody

  Rabbit Polyclonal Anti-ABCD2 Antibody  
WB Suggested Anti-ABCD2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: HepG2 cell lysate; ABCD2 is supported by BioGPS gene expression data to be expressed in HepG2 Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

ABCD2 / ALDR antibody

  Rabbit Polyclonal Anti-ABCD2 Antibody  
WB Suggested Anti-ABCD2 Antibody Titration: 0.2-1 ug/ml; Positive Control: THP-1 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ye, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

ABCD2 / ALDR (Center) antibody

Western blot analysis of ABCD2 Antibody (Center) (Cat. #AP50018PU-N) in mouse brain tissue lysates (35 µg/lane). ABCD2 (arrow) was detected using the purified Pab. Rabbit Ig Aff - Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

ABCD2 / ALDR (C-term) antibody

ABCD2 Antibody (C-term) (Cat. #AP50019PU-N)immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ABCD2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

ABCD2 / ALDR (N-term) antibody

ABCD2 / ALDR Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

ABCD2 / ALDR antibody

Human THP-1; WB Suggested Anti-ABCD2 Antibody Titration: 0.2-1 ug/ml. Positive Control: THP-1 cell lysate; ABCD2 antibody - middle region (ARP43658_P050) in Human THP-1 cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

CRISPR

Catalog No. Species Donor Vector  

ABCD2 - human gene knockout kit via CRISPR

ABCD2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

ABCD2 - human gene knockout kit via CRISPR

ABCD2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

ABCD2 - human gene knockout kit via CRISPR

ABCD2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

ABCD2 - human gene knockout kit via CRISPR

ABCD2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Abcd2 - mouse gene knockout kit via CRISPR

Abcd2 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Abcd2 - mouse gene knockout kit via CRISPR

Abcd2 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Abcd2 - mouse gene knockout kit via CRISPR

Abcd2 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Abcd2 - mouse gene knockout kit via CRISPR

Abcd2 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

ABCD2 overexpression lysate

ABCD2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, ABCD2 (mGFP-tagged) - Human ATP-binding cassette, sub-family D (ALD), member 2 (ABCD2), 200 uL, >10^7 TU/mL

Lenti ORF particles, ABCD2 (mGFP-tagged) - Human ATP-binding cassette, sub-family D (ALD), member 2 (ABCD2), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, ABCD2 (Myc-DDK tagged) - Human ATP-binding cassette, sub-family D (ALD), member 2 (ABCD2) , 200 uL, >10^7 TU/mL

Lenti ORF particles, ABCD2 (Myc-DDK tagged) - Human ATP-binding cassette, sub-family D (ALD), member 2 (ABCD2) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

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