ABCD4 / PXMP1L antibody

Principal name

ABCD4 / PXMP1L antibody

Alternative names for ABCD4 / PXMP1L antibody

Peroxisomal membrane protein 69, Peroxisomal membrane protein 1-like, P70R, PMP69, ATP-binding cassette sub-family D member 4

SwissProt ID

O14678 (Human), O89016 (Mouse)

Gene ID

5826 (ABCD4), 1035826 (ybhE)

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Ms (Mouse), Rt (Rat), Ze (Zebrafish), Eq (Equine), GP (Guinea Pig), Rb (Rabbit), Por (Porcine), Ye (Yeast)

Available hosts

Rabbit, Goat

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of ABCD4 / PXMP1L antibody

ABCD4 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. Alternative splicing results in at least two different transcript variants, one which is protein-coding and one which is probably not protein-coding.

General readings

Asheuer M, Bieche I, Laurendeau I, Moser A, Hainque B, Vidaud M, Aubourg P.
Decreased expression of ABCD4 and BG1 genes early in the pathogenesis of Xlinked adrenoleukodystrophy.
Hum Mol Genet. 2005 May 15;14(10):1293-303
PMID: 15800013

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ABCD4 / PXMP1L antibody

TA305757 (0.3ug/ml) staining of  Jurkat lysate (35?g protein in RIPA buffer). Primary incubation was 1 hour. Detected with chemiluminescence. Goat Aff - Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ABCD4 / PXMP1L antibody

Western blot analysis of Jurkat cells (Lane 1: 60ug lysate) and THP1 cells (Lane 2: 50ug lysate) with anti-ABCD4 antibody diluated at 1:1000. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

ABCD4 / PXMP1L antibody

Western blot analysis of extracts from HepG2 cells, using ABCD4 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

ABCD4 / PXMP1L antibody

Predicted band size: 69 kDa. Positive control: Jurkat cell lysate. Recommended dilution: 1/500-2000. (Gel: 10%SDS-PAGE Lysate: 40 ug per lane Primary antibody: 1/700 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

ABCD4 / PXMP1L antibody

Predicted band size: 69 kDa. Positive control: Jurkat cell lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lysate: 40 ug per lane Primary antibody: 1/300 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 40 seconds) Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

ABCD4 / PXMP1L antibody

WB Suggested Anti-ABCD4 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: 721_B cell lysate; ABCD4 is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

ABCD4 / PXMP1L antibody

WB Suggested Anti-ABCD4 Antibody Titration: 1.25ug/ml; Positive Control: HepG2 cell lysate; ABCD4 is supported by BioGPS gene expression data to be expressed in HepG2 Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ye WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ABCD4 / PXMP1L antibody

ABCD4 polyclonal antibody ( Cat # PAB11482 ) ( 0.3 µg/ml ) staining of Jurkat lysate ( 35 µg protein in RIPA buffer ). Primary incubation was 1 hour. Detected with chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

ABCD4 / PXMP1L antibody

Human 721_B; WB Suggested Anti-ABCD4 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: 721_B cell lysate. ABCD4 is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells.; ABCD4 antibody - N-terminal region (ARP43655_P050) in Human 721_B cells using Western Blot Rabbit Aff - Purified Hu, Ms, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

ABCD4 / PXMP1L antibody

Human HepG2; WB Suggested Anti-ABCD4 Antibody Titration: 1.25ug/ml. Positive Control: HepG2 cell lysate. ABCD4 is supported by BioGPS gene expression data to be expressed in HepG2.; ABCD4 antibody - C-terminal region (ARP43656_T100) in Human HepG2 cells using Western Blot Rabbit Purified Bov, Can, Hu, Ms, Rt WB
0.1 mg / €310.00
  AVIVA Systems Biology

ABCD4 / PXMP1L antibody

Immunohistochemical analysis of ABCD4 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu, Ms, Rt P, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

ABCD4 / PXMP1L antibody

Immunohistochemical analysis of ABCD4 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

ABCD4 / PXMP1L antibody

Immunohistochemical analysis of ABCD4 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

ABCD4 / PXMP1L antibody

Western Blot: ABCD4 Antibody [NBP1-20872]-(0.3µg/ml) staining of Jurkat lysate (35µg protein in RIPA buffer). Goat IgG Aff - Purified Hu E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

ABCD4 / PXMP1L antibody

Western Blot: ABCD4 Antibody [NBP1-59397] - This Anti-ABCD4 antibody was used in Western Blot of 721_B tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €440.00
  Novus Biologicals Inc.

ABCD4 / PXMP1L antibody

Western Blot: ABCD4 Antibody [NBP1-59807] - This Anti-ABCD4 antibody was used in Western Blot of HepG2 tissue lysate at a concentration of 1.25ug/ml. Rabbit Purified Can, Hu, Ms, Rt WB
0.1 mg / €360.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

ABCD4 / PXMP1L (transcript variant 1)

ABCD4 / PXMP1L Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

17 Item(s)

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