ABCD4 / PXMP1L antibody

Principal name

ABCD4 / PXMP1L antibody

Alternative names for ABCD4 / PXMP1L antibody

Peroxisomal membrane protein 69, Peroxisomal membrane protein 1-like, P70R, PMP69, ATP-binding cassette sub-family D member 4

SwissProt ID

O14678 (Human), O89016 (Mouse)

Gene ID

5826 (ABCD4), 19300 (Abcd4)

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Ms (Mouse), Rt (Rat), Ze (Zebrafish), Eq (Equine), GP (Guinea Pig), Rb (Rabbit), Por (Porcine), Ye (Yeast)

Available hosts

Rabbit, Goat

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of ABCD4 / PXMP1L antibody

ABCD4 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. Alternative splicing results in at least two different transcript variants, one which is protein-coding and one which is probably not protein-coding.

General readings

Asheuer M, Bieche I, Laurendeau I, Moser A, Hainque B, Vidaud M, Aubourg P.
Decreased expression of ABCD4 and BG1 genes early in the pathogenesis of Xlinked adrenoleukodystrophy.
Hum Mol Genet. 2005 May 15;14(10):1293-303
PMID: 15800013

Items 1 to 20 of 22 total

per page
Page:
  1. 1
  2. 2

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ABCD4 / PXMP1L antibody

  Goat Anti-ABCD4 Antibody  
TA305757 (0.3ug/ml) staining of  Jurkat lysate (35?g protein in RIPA buffer). Primary incubation was 1 hour. Detected with chemiluminescence. Goat Aff - Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ABCD4 / PXMP1L antibody

  Rabbit anti-ABCD4 polyclonal antibody  
Western blot analysis of Jurkat cells (Lane 1: 60ug lysate) and THP1 cells (Lane 2: 50ug lysate) with anti-ABCD4 antibody diluated at 1:1000. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

ABCD4 / PXMP1L antibody

  Rabbit polyclonal anti-ABCD4 antibody  
Western blot analysis of extracts from HepG2 cells, using ABCD4 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

ABCD4 / PXMP1L antibody

  Anti-ABCD4 Rabbit Polyclonal Antibody  
Predicted band size: 69 kDa. Positive control: Jurkat cell lysate. Recommended dilution: 1/500-2000. (Gel: 10%SDS-PAGE Lysate: 40 ug per lane Primary antibody: 1/700 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

ABCD4 / PXMP1L antibody

  Anti-ABCD4 Rabbit Polyclonal Antibody  
Predicted band size: 69 kDa. Positive control: Jurkat cell lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lysate: 40 ug per lane Primary antibody: 1/300 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 40 seconds) Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

ABCD4 / PXMP1L antibody

  Rabbit Polyclonal Anti-ABCD4 Antibody  
WB Suggested Anti-ABCD4 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: 721_B cell lysate; ABCD4 is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

ABCD4 / PXMP1L antibody

  Rabbit Polyclonal Anti-ABCD4 Antibody  
WB Suggested Anti-ABCD4 Antibody Titration: 1.25ug/ml; Positive Control: HepG2 cell lysate; ABCD4 is supported by BioGPS gene expression data to be expressed in HepG2 Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ye WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

ABCD4 - human gene knockout kit via CRISPR

ABCD4 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

ABCD4 - human gene knockout kit via CRISPR

ABCD4 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

ABCD4 - human gene knockout kit via CRISPR

ABCD4 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

ABCD4 - human gene knockout kit via CRISPR

ABCD4 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Abcd4 - mouse gene knockout kit via CRISPR

Abcd4 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Abcd4 - mouse gene knockout kit via CRISPR

Abcd4 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Abcd4 - mouse gene knockout kit via CRISPR

Abcd4 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Abcd4 - mouse gene knockout kit via CRISPR

Abcd4 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

ABCD4 / PXMP1L (transcript variant 1)

  Recombinant protein of human ATP-binding cassette, sub-family D (ALD), member 4 (ABCD4), transcript variant 1  
ABCD4 / PXMP1L Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, ABCD4 (mGFP-tagged) - Human ATP-binding cassette, sub-family D (ALD), member 4 (ABCD4), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, ABCD4 (mGFP-tagged) - Human ATP-binding cassette, sub-family D (ALD), member 4 (ABCD4), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,260.00
  OriGene Technologies, Inc.

Lenti ORF particles, ABCD4 (Myc-DDK tagged) - Human ATP-binding cassette, sub-family D (ALD), member 4 (ABCD4), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, ABCD4 (Myc-DDK tagged) - Human ATP-binding cassette, sub-family D (ALD), member 4 (ABCD4), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €1,130.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Abcd4 (GFP-tagged) - Mouse ATP-binding cassette, sub-family D (ALD), member 4 (Abcd4), 200 uL, >10^7 TU/mL

Lenti ORF particles, Abcd4 (GFP-tagged) - Mouse ATP-binding cassette, sub-family D (ALD), member 4 (Abcd4), 200 uL, >10^7 TU/mL  
200 µl / €1,260.00
  OriGene Technologies, Inc.

Lenti ORF particles, Abcd4 (GFP-tagged) - Mouse ATP-binding cassette, sub-family D (ALD), member 4 (cDNA clone MGC:60642 IMAGE:30012556), 200 uL, >10^7 TU/mL

Lenti ORF particles, Abcd4 (GFP-tagged) - Mouse ATP-binding cassette, sub-family D (ALD), member 4 (cDNA clone MGC:60642 IMAGE:30012556), 200 uL, >10^7 TU/mL  
200 µl / €1,170.00
  OriGene Technologies, Inc.

Items 1 to 20 of 22 total

per page
Page:
  1. 1
  2. 2
  • LinkedIn