ABCG1 antibody

Principal name

ABCG1 antibody

Alternative names for ABCG1 antibody

ABC8, WHT1, ATP-binding cassette sub-family G member 1, White protein homolog

SwissProt ID

P45844 (Human), Q64343 (Mouse)

Gene ID

9619 (ABCG1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Hst (Hamster)

Available hosts

Rabbit, Mouse

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Frozen Sections (C), Immunoprecipitation (IP), Flow Cytometry (F)

Background of ABCG1 antibody

ATP-binding cassette (ABC) transporter ABCG1 (ABC8) is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. Conversely, lipid efflux in cholesterol-laden macrophages, mediated by the cholesterol acceptor HDL(3), suppresses the expression of ABCG1. Immunocytochemical and flow cytometric analyses revealed that ABCG1 is expressed on the cell surface and in intracellular compartments of cholesterol-laden macrophages. Results demonstrate a regulator function for ABCG1 in cholesterol and phospholipid transport define a biologic activity for ABC transporters in macrophages (1). ABC transporters belonging to the ABCG (White) subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be critically involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells (2) Studies show that treatment with Rhodobacter sphaeroiders LPS, an LPS antagonist, or PD169316, a specific p38 MAP kinase inhibitor, prevented the induction of ABCA1 by LPS. Therefore, this suggests that both transport of LPS from the plasma membrane to an intracellular site and activation of p38 MAP kinase are involved in the LPS-mediated induction of ABCA1 (3).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ABCG1 antibody

Predicted band size: 76 kDa. Positive control: HT-29 cell lysate. Recommended dilution: 1/500-2000. (Gel: 10%SDS-PAGE Lysate: 40 ug per lane Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 2 minutes) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

ABCG1 antibody

Predicted cell location: Cytoplasm . Positive control: Human breast and colon cancer tissue . Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded human breast cancer tissue using ABCG1 antibody at dilution 1/25, on the right is treated with the synthetic peptide. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

ABCG1 antibody

AP17071PU-N ABCG1 Antibody staining of Formalin-fixed and paraffin-embedded human hepatocarcinoma using peroxidase followed by DAB staining. Rabbit Ig Purified Hu F, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

ABCG1 antibody

Detection limit for recombinant GST tagged ABCG1 is approximately 0.1ng/ml as a capture antibody. Mouse IgG1 2E11 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

ABCG1 antibody

ABCG1 Mouse IgG1 2H8 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

ABCG1 antibody

Detection of ABCG1 in mouse peritoneal macrophages ( 40 µg ) using ABCG1 polyclonal antibody ( Cat # PAB12503 ). Lane 1 : positive ABCG1 control, lane 2 : 10 µM 22- ( R ) -hydrocholesterol treated macrophages, Lane 3 : 100 nM T0901713 ( LXRa ligand ) treated macrophages, and Lane 4 : 500 nM T091713 ( LXRa ligand ) treated macrophages. Rabbit Hu, Ms C, WB
0.1 ml / €470.00
  Abnova Taiwan Corp.

ABCG1 antibody

ABCG1 Rabbit IgG Aff - Purified Hu, Ms, Rt WB
0.1 mg / €290.00
  Boster Immunoleader

ABCG1 antibody

Western blot analysis of ABCG1 expression in HepG2 (A) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

ABCG1 antibody

Western blot analysis of ABCG1 expression in HepG2 (A) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

ABCG1 antibody

Western blot analysis of ABCG1 expression in HepG2 (A) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

ABCG1 antibody

Staining of lung, alveolar macrophages using NB400-132. Rabbit Biotin Hu, Ms P, WB
0.1 ml / €360.00
  Novus Biologicals Inc.

ABCG1 antibody

ABCG1 Rabbit DyLight488 Hu, Ms P, WB
0.1 ml / €390.00
  Novus Biologicals Inc.

ABCG1 antibody

Staining of lung, alveolar macrophages using NB400-132. Rabbit HRP Hu, Ms WB
0.1 ml / €390.00
  Novus Biologicals Inc.

ABCG1 control peptide

ABCG1 Purified Hu, Ms
50 µg / €140.00
  Novus Biologicals Inc.

ABCG1 antibody

ABCG1 Rabbit Aff - Purified Hu, Ms ICC/IF, P, WB
25 µl / €200.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

ABCG1 (transcript variant 2)

ABCG1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

ABCG1

ABCG1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

ABCG1

ABCG1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

ABCG1

ABCG1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

ABCG1

ABCG1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

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