ABCG5 antibody

Principal name

ABCG5 antibody

Alternative names for ABCG5 antibody

Sterolin 1, ATP-binding cassette sub-family G member 5

SwissProt ID

Q99PE8 (Mouse), Q9H222 (Human)

Gene ID

64240 (ABCG5), 27409 (Abcg5)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), Frozen Sections (C), Flow Cytometry (F)

Background of ABCG5 antibody

ABCG5(Atp-binding cassette, subfamily g, member 5) also known as STEROLIN 1, is a protein that in humans is encoded by the ABCG5 gene. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters.  This protein is a member of the White subfamily. The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols. The ABCG5 gene contains 13 exons and spans about 28 kb.The ABCG5 gene is mapped on 2p21. It is expressed in a tissue-specific manner in the liver, colon, and intestine. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG8. Mutations in this gene may contribute to sterol accumulation and atheroschlerosis, and have been observed in patients with sitosterolemia. Small (2003) reviewed the role of ABC transporters in secretion of cholesterol from liver into bile, particularly the role of ABCG5/ABCG8.The ABCG5 and ABCG8 genes are an example of closely neighboring genes in a head-to-head orientation that, when mutated, cause the same phenotype.

General readings

"The human ATP-binding cassette (ABC) transporter superfamily." Dean M, Rzhetsky A, Allikmets R. Genome Res. 2001 Jul;11(7):1156-66. Review.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ABCG5 antibody

Western Blot: ABCG5 Antibody (1B5E10) [TA336947] - Western blot analysis of ABCG5 in (1) HEK293 and (2) ABCG5 hIgGFc transfected HEK293 cell lysate. Mouse IgG1 1B5E10 Purified Hu C, E, F, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

ABCG5 antibody

Predicted cell location: Cytoplasm . Positive control: Human liver cancer tissue . Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded human liver cancer tissue using ABCG5 antibody at dilution 1/20, on the right is treated with the synthetic peptide. (Original magnification:x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

ABCG5 antibody

WB Suggested Anti-ABCG5 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: Human Spleen Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

ABCG5 antibody

Western blotting of human spleen lysate using AP44701PU-N ABCG5 antibody Rabbit Aff - Purified Hu WB
50 µg / €350.00
  Acris Antibodies GmbH

ABCG5 antibody

ABCG5 Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

ABCG5 antibody

ABCG5 Rabbit IgG Aff - Purified Hu WB
0.1 mg / €290.00
  Boster Immunoleader

CRISPR

Catalog No. Species Donor Vector  

Abcg5 - mouse gene knockout kit via CRISPR

Abcg5 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Abcg5 - mouse gene knockout kit via CRISPR

Abcg5 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Abcg5 - mouse gene knockout kit via CRISPR

Abcg5 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Abcg5 - mouse gene knockout kit via CRISPR

Abcg5 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

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