ABL2 antibody

Principal name

ABL2 antibody

Alternative names for ABL2 antibody

ABLL, ARG, Abelson murine leukemia viral oncogene homolog 2, Abelson-related gene protein, Tyrosine kinase ARG, Tyrosine-protein kinase ABL2

SwissProt ID

P42684 (Human), Q4JIM5 (Mouse)

Gene ID

27 (ABL2), 100279512 (grf2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunoprecipitation (IP), Frozen Sections (C)

Background of ABL2 antibody

ABL2 (ARG, Abl-related gene), together with c-Abl, forms the Abl family of mammalian non-receptor tyrosine kinases. ABL2 and c-Abl share 89%, 90 and 93% identity in their SH3, SH2 and tyrosine domain, but only 29% identity in the carboxy-terminal half. The human c-Abl and ABL2 genes are expressed ubiquitously. ABL2 had been detected predominantly in the cytoplasm, whereas c-Abl shows both cytoplasmic and nuclear localization. c-Abl is involved in two different chromosomal translocations present in human leukemias, which generate Bcr-Abl and TEL-Abl. Recently, TEL-ARG fusion transcripts have also been identified in acute myeloid leukemias (AML). The Abl family kinases may also interact with receptor tyrosine signaling pathways and regulate cellular function such as cell cycle progression, gene transcription and organization of the actin cytoskeletons in neurons.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ABL2 antibody

Immunohistochemistry: ABL2 Antibody - Distinct nuclear expression was often detected in neuronal cells, glial cells and primary spermatocytes. Weak to moderate nuclear expression, often combined with cytoplasmic positivity, was observed in normal and malignant tissues. Malignant gliomas exhibited nuclear staining of varying intensity.  Image and statement courtesy of the Human Protein Atlas (HPA).  View all of the IHC expression profiles performed by the Human Protein Atlas. Rabbit IgG Purified Hu E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ABL2 antibody

Proximity Ligation Analysis (PLA) of protein-protein interactions between NCK1 and ABL2. HeLa cells were stained with anti-NCK1 rabbit purified polyclonal 1:1200 and anti-ABL2 mouse monoclonal antibody 1:50. Signals were detected by Duolink® 30 Detection Kit 613(red), and nuclei were counterstained with DAPI (blue). Each red dot represents the detection of protein-protein interaction complex. Mouse IgG2a 6D5 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

ABL2 antibody

Immunoperoxidase of monoclonal antibody to ABL2 on formalin-fixed paraffin-embedded human cerebellum. [antibody concentration 1.5 ug/ml] Mouse IgG3 5C6 Purified Hu E, ICC/IF, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

ABL2 antibody

Predicted band size: 128 kDa. Positive control: Hela and Jurkat cell lysate. Recommended dilution: 1/500-2000. (Gel: 8%SDS-PAGE Lane1: Hela cell lysate Lane2: Jurkat cell lysate Lysates: 40 ug per lane Primary antibody: 1/400 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 2 minutes) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

ABL2 antibody

Immunofluorescence staining of methanol-fixed Hela cells using ABL2 antibody Cat.-No AM06165SU-N showing cytoplasm localization. Mouse IgG1 1H1B11 Ascites Hu E, ICC/IF, WB
0.1 ml / €360.00
  Acris Antibodies GmbH

ABL2 antibody

Immunofluorescence analysis of NIH/3T3 cells using ABL2 antibody Cat.-No AM06500SU-N (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin. Mouse IgG1 1H1 Ascites Hu, Ms E, ICC/IF, WB
0.1 ml / €400.00
  Acris Antibodies GmbH

ABL2 (Center) antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

ABL2 antibody

Western blot analysis of anti-ABL Antibody (Cat.#AP12556PU-N) in A2058 cell line lysates (35ug/lane). ABL(arrow) was detected using the purified Pab. Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

ABL2 antibody

Western Blot analysis of ABL2 expression in transfected 293T cell line (H00000027-T02) by ABL2 MaxPab polyclonal antibody.

Lane 1: ABL2 transfected lysate(126.70 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

ABL2 antibody

ABL2 Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

ABL2 antibody

ABL2 monoclonal antibody (M04), clone 3G3 Western Blot analysis of ABL2 expression in Hela NE ( Cat # L013V3 ). Mouse IgG2a 3G3 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

ABL2 antibody

Western Blot analysis of ABL2 expression in transfected 293T cell line by ABL2 monoclonal antibody (M05), clone 3D2.

Lane 1: ABL2 transfected lysate(127 KDa).
Lane 2: Non-transfected lysate. Mouse IgG2a 3D2 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

ABL2 antibody

Detection limit for recombinant GST tagged ABL2 is approximately 1ng/ml as a capture antibody. Mouse IgG2a 2H8 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

ABL2 antibody

ABL2 monoclonal antibody (M08), clone 5C7 Western Blot analysis of ABL2 expression in Jurkat ( Cat # L017V1 ). Mouse IgG3 5C7 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

ABL2 antibody

ABL2 monoclonal antibody (M10), clone 3E4 Western Blot analysis of ABL2 expression in K-562 ( Cat # L009V1 ). Mouse IgG3 3E4 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

ABL2 antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the ABL2 polyclonal antibody ( Cat # PAB2610 ) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma. Rabbit Hu E, P, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

ABL2 antibody

Immunohistochemistry: ABL2 Antibody [23270002] - Distinct nuclear expression was often detected in neuronal cells, glial cells and primary spermatocytes. Weak to moderate nuclear expression, often combined with cytoplasmic positivity, was observed in normal and malignant tissues. Malignant gliomas exhibited nuclear staining of varying intensity.  Image and statement courtesy of the Human Protein Atlas (HPA).  View all of the IHC expression profiles performed by the Human Protein Atlas. Rabbit Hu E, P, WB
50 µg / €440.00
  Novus Biologicals Inc.

ABL2 antibody

Western Blot and Immunoprecipitation: ARG Antibody [NBP1-18875] - Whole cell lysate from HeLa cells. ARG was also immunoprecipitated by rabbit anti-ARG antibodies NBP1-18876 and NBP1-18877. Rabbit IgG Aff - Purified Hu IP, WB
0.1 ml / €440.00
  Novus Biologicals Inc.

ABL2 antibody

Western Blot: ARG Antibody [NBP1-18876]-  Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Affinity purified rabbit anti-ARG antibody used for IP at 3 mcg/mg lysate. ARG was also immunoprecipitated by rabbit anti-ARG antibodies NBP1-18875 and NBP1-18877, which recognize other epitopes. Rabbit IgG Aff - Purified Hu IP, WB
0.1 ml / €440.00
  Novus Biologicals Inc.

ABL2 antibody

Western Blot: ARG Antibody [NBP1-18877]- Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-ARG antibody used for IP at 3 mcg/mg lysate. ARG was also immunoprecipitated by rabbit anti-ARG antibodies NBP1-18875 and NBP1-18876, which recognize upstream epitopes. Rabbit IgG Aff - Purified Hu IP, WB
0.1 ml / €440.00
  Novus Biologicals Inc.

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