ACD antibody

Principal name

ACD antibody

Alternative names for ACD antibody

PIP1, PTOP, TINT1, TPP1, Adrenocortical dysplasia protein homolog

SwissProt ID

Q4FZR5 (Rat), Q5EE38 (Mouse), Q96AP0 (Human)

Gene ID

65057 (ACD), 497652 (Acd), 307798

Available reactivities

Hu (Human), Ms (Mouse)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunoprecipitation (IP), Flow Cytometry (F)

Background of ACD antibody

ACD is a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere.This gene encodes a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere. Multiple transcript variants encoding different isoforms have been found for this gene. This gene, which is also referred to as TPP1, is distinct from the unrelated TPP1 gene on chromosome 11, which encodes tripeptidyl-peptidase I.

General readings

"Urogenital and caudal dysgenesis in adrenocortical dysplasia (acd) mice is caused by a splicing mutation in a novel telomeric regulator." Keegan C.E., Hutz J.E., Else T., Adamska M., Shah S.P., Kent A.E., Howes J.M., Beamer W.G., Hammer G.D. Hum. Mol. Genet. 14:113-123(2005)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ACD antibody

  ACD mouse monoclonal antibody, clone OTI2B1 (formerly 2B1)  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-ACD mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA504379) Mouse IgG1 OTI2B1 Purified Hu P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

ACD (C-term) antibody

  Rabbit Polyclonal Anti-Acd Antibody  
WB Suggested Anti-Acd Antibody Titration: 0.2-1 ug/ml; Positive Control: Mouse Muscle Rabbit Aff - Purified Ms WB
50 µg / €325.00
  OriGene Technologies, Inc.

ACD antibody

  Rabbit Polyclonal Anti-ACD Antibody - C-terminal region  
WB Suggested Anti-ACD Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: Human brain Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

ACD antibody

  Rabbit Polyclonal Anti-ACD Antibody - middle region  
WB Suggested Anti-ACD Antibody Titration: 0.2-1 ug/ml; Positive Control: NCI-H226 cell lysate Rabbit Aff - Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

ACD antibody

  ACD mouse monoclonal antibody, clone OTI1C8 (formerly 1C8)  
Anti-ACD mouse monoclonal antibody (TA504201) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ACD(RC204381). Mouse IgG2b OTI1C8 Purified Hu ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

ACD antibody

  ACD mouse monoclonal antibody, clone OTI1A2 (formerly 1A2)  
Anti-ACD mouse monoclonal antibody (TA504406) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ACD(RC204381). Mouse IgG1 OTI1A2 Purified Hu F, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CRISPR

Catalog No. Species Donor Vector  

ACD - human gene knockout kit via CRISPR

ACD - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

ACD - human gene knockout kit via CRISPR

ACD - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

ACD - human gene knockout kit via CRISPR

ACD - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

ACD - human gene knockout kit via CRISPR

ACD - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Acd - mouse gene knockout kit via CRISPR

Acd - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Acd - mouse gene knockout kit via CRISPR

Acd - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Acd - mouse gene knockout kit via CRISPR

Acd - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Acd - mouse gene knockout kit via CRISPR

Acd - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

ACD (transcript variant 1)

  Recombinant protein of human adrenocortical dysplasia homolog (mouse) (ACD), transcript variant 1  
ACD Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

ACD (transcript variant 2)

  Recombinant protein of human adrenocortical dysplasia homolog (mouse) (ACD), transcript variant 2  
ACD Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

ACD overexpression lysate

ACD overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

ACD overexpression lysate

ACD overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

ACD overexpression lysate

ACD overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, ACD (mGFP-tagged) - Human adrenocortical dysplasia homolog (mouse) (ACD), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, ACD (mGFP-tagged) - Human adrenocortical dysplasia homolog (mouse) (ACD), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

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