ACE2 antibody

Principal name

ACE2 antibody

Alternative names for ACE2 antibody

Angiotensin-converting enzyme 2, ACE-related carboxypeptidase, Angiotensin-converting enzyme homolog

SwissProt ID

Q58DD0 (Bovin), Q5EGZ1 (Rat), Q8R0I0 (Mouse), Q9BYF1 (Human)

Gene ID

59272 (ACE2), 70008 (Ace2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Por (Porcine)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Paraffin Sections (P), Flow Cytometry (F), Frozen Sections (C)

Background of ACE2 antibody

ACE2 cDNA encodes a deduced 805-amino acid protein containing a potential 17-amino acid N-terminal signal peptide and a putative 22-amino acid C-terminal membrane anchor. It also possesses a zinc metalloprotease consensus sequence and a conserved glutamine residue that may function as a third zinc ligand. ACE2 is expressed predominantly in vascular endothelial cells of the heart and kidney. ACE converts angiotensin I to angiotensin II, ACE2 converts angiotensin I to angiotensin 1-9, which has 9 amino acids. Angiotensin II is a potent blood vessel constrictor, while angiotensin 1-9 does not impact blood vessels but is cleaved by ACE to a shorter peptide, angiotensin 1-7, which is a blood vessel dilator. Spike (S) proteins of coronaviruses, including the SARS coronavirus, bind with cellular receptors to mediate infection of target cells. ACE2 binds the S1 domain of the SARS coronavirus S protein. SARS coronavirus replicates efficiently on ACE2-transfected but not mock-transfected 293T cells. Anti-ACE2 but not anti-ACE1 antibody blocks viral replication on Vero E6 cells. It has been proposed that ACE2 is a functional receptor for SARS coronavirus.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ACE2 antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-ACE2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA803841) Mouse IgG2a OTI4D2 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

ACE2 antibody

Western blot analysis of ACE2 in human kidney lysate with ACE2 antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml. Rabbit IgG Aff - Purified Hu, Ms E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ACE2 (C-term) antibody

Western blot analysis of ACE2 in human kidney lysate with ACE2 antibody at 0.5 (lane A), 1 (lane B), and 2 (lane C) ug/ml, respectively. Rabbit IgG Aff - Purified Hu E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ACE2 (N-term) antibody

Western blot analysis of ACE2 in human kidney lysate with ACE2 antibody at 1 ug/ml. Rabbit IgG Aff - Purified Hu E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ACE2 antibody

Western blot analysis of ACE2 in human kidney lysate with ACE2 antibody (IN2) at 2 ug/ml. Rabbit IgG Aff - Purified Hu E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ACE2 antibody

Predicted cell location: Cytoplasm. Positive control: Human brain and thyroid cancer tissue. Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded human brain tissue using ACE2 antibody at dilution 1/30, on the right is treated with the fusion protein. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

ACE2 antibody

Predicted cell location: Cytoplasm, Cell membrane. Positive control: Human esophagus and lung cancer tissue.Recommended dilution: 1/100-300 The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissues  using ACE2 antibody at dilution 1/200, on the right is immunohistochemistry of paraffin-embedded Human lung cancer tissues using ACE2 antibody at dilution 1/200. (Original magnification: x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

ACE2 antibody

Predicted cell location: Cytoplasm, Cell membrane. Positive control: Human stomach and liver cancer tissue.Recommended dilution: 1/25-100 The image on the left is immunohistochemistry of paraffin-embedded Human stomach cancer tissue  using ACE2 antibody at dilution 1/40, on the right is immunohistochemistry of paraffin-embedded Human liver cancer tissue using ACE2 antibody at dilution 1/40. (Original magnification: x100) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

ACE2 antibody

ACE2 (SARS Receptor) Antibody (Center) (Cat. #TA325141) western blot analysis in 293,K562,MCF-7,SK-BR-3,T47D,MDA-MB-453 cell line and mouse testis tissue lysates (35ug/lane).This demonstrates the ACE2 antibody detected the ACE2 protein (arrow). Mouse IgM 881CT16.4.4 Purified Hu WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

ACE2 antibody

ACE2 (SARS Receptor) Antibody (Center) (Cat. #TA328186) western blot analysis in MDA-MB-453,MCF-7 cell line lysates (35ug/lane).This demonstrates the ACE2 (SARS Receptor) antibody detected the ACE2 (SARS Receptor) protein (arrow). Mouse IgM 881CT16.4.4 Ascites Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

ACE2 antibody

Western blot analysis of ACE2 expression in HeLa cells Rabbit IgG Purified Ms WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ACE2 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ACE2 (RC208442, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ACE2. Mouse IgG2a OTI1D2 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

ACE2 antibody

Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-ACE2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA803844) Mouse IgG1 OTI4C5 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

ACE2 antibody

Immunohistochemical staining of paraffin-embedded Human breast tissue within the normal limits using anti-ACE2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA803906) Mouse IgG1 OTI1D6 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

ACE2 antibody

Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-ACE2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA804152) Mouse IgG1 OTI1G4 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

ACE2 (C-term) antibody

ACE2 Mouse IgG1 11A31 Purified Hu P, WB
0.1 mg / €440.00
  Acris Antibodies GmbH

ACE2 antibody

Immunohistochemical staining of human kidney woth Rabbit anti Human ACE2 antibody Cat.-No AP05885PU-N Rabbit IgG Purified Hu P, WB
0.1 mg / €330.00
  Acris Antibodies GmbH

ACE2 antibody

Figure 1. Formalin-Fixed Paraffin-Embedded (FFPE) on Kidney. Rabbit Aff - Purified Hu, Ms P, WB
50 µg / €470.00
  Acris Antibodies GmbH

ACE2 (N-term) antibody

(LEFT)Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. (RIGHT)Formalin-fixed and paraffin-embedded human testis tissue reacted with ACE2 (SARS Receptor) Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

ACE2 antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

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