Acetyl-CoA carboxylase 1 antibody

Principal name

Acetyl-CoA carboxylase 1 antibody

Alternative names for Acetyl-CoA carboxylase 1 antibody

ACACA, ACAC, ACC1, ACCA

SwissProt ID

P11497 (Rat), Q13085 (Human), Q5SWU9 (Mouse)

Gene ID

31 (ACACA), 107476 (Acaca)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Por (Porcine), Sh (Sheep)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C)

Background of Acetyl-CoA carboxylase 1 antibody

Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the ratelimiting step in fatty acid synthesis. Exercise diminishes the activity of acetyl-CoA carboxylase in human muscle. ACC-alpha (ACC1) is the rate-limiting enzyme in the biogenesis of long-chain fatty acids, and ACC-beta (ACC2) may control mitochondrial fatty acid oxidation. These two isoforms of ACC control the amount of fatty acids in the cells. The catalytic function of ACC-alpha is regulated by phosphorylation (inactive) and dephosphorylation (active) of targeted Serine residues and by allosteric transformation by citrate or palmitoyl-CoA, which serve as the short-term regulatory mechanism of the enzyme. The gene encoding ACC-alpha, which maps to human chromosome 17, encodes the 265 kDa alpha form of ACC, which is the major ACC in lipogenic tissues. The catalytic core of ACC-beta is homologous to that of ACC-alpha except for an additional peptide of about 150 amino acids at the N-terminus.

General readings

Ray H. et al. Cell cycle regulation of the BRCA1/acetyl-CoA-carboxylase complex.Biochemical and Biophysical Research Communications. Volume 378, Issue 3, 16 January 2009, Pages 615-619

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Acetyl-CoA carboxylase 1 antibody

  Rabbit polyclonal ACC1 (Ab-80) antibody  
Western blot analysis of extracts from NIH/3T3 cells, treated with PMA (125ng/ml, 30mins), using ACC1 (Ab-80) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Acetyl-CoA carboxylase 1 antibody

  Rabbit polyclonal Acetyl-CoA Carboxylase (Ab-80) antibody  
Western blot analysis of extracts from NIH/3T3 cells treated with PMA (125ng/ml, 15min), using Acetyl-CoA Carboxylase (Ab-80) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Acetyl-CoA carboxylase 1 antibody

  Anti-ACACA (Phospho-Ser79) Rabbit Polyclonal Antibody  
Predicted band size: 266 kDa . Positive control: 293 cells treated with AICAR lysate. Recommended dilution: 1/ 500-1000. (Gel: 8%SDS-PAGE Lane1: 293 cells untreated with AICAR lysate Lane2: 293 cells treated with AICAR lysate Lysates: 30 ug per lane Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Acetyl-CoA carboxylase 1 antibody

  Anti-ACACA Rabbit Polyclonal Antibody  
Predicted band size: 266 kDa . Positive control: Heia and HUVEC cells lysate. Recommended dilution: 1/ 500-1000. (Gel: 8%SDS-PAGE Lane1,2: Heia and HUVEC cells lysate Lysates: 30 ug per lane Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Acetyl-CoA carboxylase 1 antibody

  Rabbit Polyclonal ACC1 Antibody  
Western blot analysis of ACC1 expression in PMA treated NIH-3T3 whole cell lysates,The lane on the left is treated with the antigen-specific peptide. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Acetyl-CoA carboxylase 1 antibody

Immunohistochemistry (IHC) analyzes of ACC1 antibody (Cat.-No.: AP06366PU-N) in paraffin-embedded human skeletal muscle brain tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Acetyl-CoA carboxylase 1 antibody

Immunohistochemistry (IHC) analyzes of ACCA antibody (Cat.-No.: AP06367PU-N) in paraffin-embedded human breast carcinoma colon carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Acetyl-CoA carboxylase 1 pSer1263 antibody

Acetyl-CoA carboxylase 1 Rabbit Serum Hu C, E, WB
0.2 ml / €400.00
  Acris Antibodies GmbH

Acetyl-CoA carboxylase 1 antibody

Detection limit for recombinant GST tagged ACACA is approximately 0.03ng/ml as a capture antibody. Mouse IgG2a 6H5 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Acetyl-CoA carboxylase 1 pSer80 antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using Acetyl-CoA Carboxylase (Phospho-Ser80) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
50 µg / €230.00
  Assay Biotech

Acetyl-CoA carboxylase 1 pSer80 antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using Acetyl-CoA Carboxylase (Phospho-Ser80) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €330.00
  Assay Biotech

Acetyl-CoA carboxylase 1 pSer80 antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using ACC1 (Phospho-Ser80) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
50 µg / €230.00
  Assay Biotech

Acetyl-CoA carboxylase 1 pSer80 antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using ACC1 (Phospho-Ser80) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €330.00
  Assay Biotech

Acetyl-CoA carboxylase 1 antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using Acetyl-CoA Carboxylase (Ab-80) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
50 µg / €230.00
  Assay Biotech

Acetyl-CoA carboxylase 1 antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using Acetyl-CoA Carboxylase (Ab-80) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €330.00
  Assay Biotech

Acetyl-CoA carboxylase 1 antibody

Immunohistochemistry analysis of paraffin-embedded human skeletal muscle tissue, using ACC1 (Ab-80) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
50 µg / €230.00
  Assay Biotech

Acetyl-CoA carboxylase 1 antibody

Immunohistochemistry analysis of paraffin-embedded human skeletal muscle tissue, using ACC1 (Ab-80) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €330.00
  Assay Biotech

Acetyl-CoA carboxylase 1 antibody

Immunohistochemical analysis of ACC alpha staining in human colon cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Bov, Hu, Ms, Por, Rt, Sh P, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

Acetyl-CoA carboxylase 1 antibody

Immunohistochemical analysis of ACC alpha staining in human colon cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Bov, Hu, Ms, Por, Rt, Sh P, WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

Acetyl-CoA carboxylase 1 antibody

Immunohistochemical analysis of ACC alpha staining in human colon cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Bov, Hu, Ms, Por, Rt, Sh P, WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

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