Acetyl-CoA carboxylase 2 antibody

Principal name

Acetyl-CoA carboxylase 2 antibody

Alternative names for Acetyl-CoA carboxylase 2 antibody

ACACB, ACC2, ACCB

SwissProt ID

O00763 (Human)

Gene ID

32 (ACACB)

Available reactivities

Hu (Human)

Available hosts

Goat, Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB)

Background of Acetyl-CoA carboxylase 2 antibody

Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. Exercise diminishes the activity of acetyl-CoA carboxylase in human muscle. ACC alpha (ACC1) is the rate-limiting enzyme in the biogenesis of long-chain fatty acids, and ACC beta (ACC2) is thought to control mitochondrial fatty acid oxidation. These two isoforms of ACC control the amount of fatty acids in the cells. ACC beta is thought to control fatty acid oxidation by means of the ability of malonyl-CoA to inhibit carnitine-palmitoyl-CoA transferase I, the rate-limiting step in fatty acid uptake and oxidation by mitochondria. The gene encoding ACC beta maps to human chromosome 12 and encodes a mitochondiral protein expressed in heart and skeletal muscle. The catalytic core of ACC beta is homologous to that of ACC alpha, except for an additional peptide of about 150 amino acids at the N-terminus

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Acetyl-CoA carboxylase 2 antibody

  Goat Anti-ACACB Antibody  
(1.5ug/ml) as the reporter with capture rabbit antibody at 5ug/ml. Goat Aff - Purified Hu E
0.1 mg / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

ACACB - human gene knockout kit via CRISPR

ACACB - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

ACACB - human gene knockout kit via CRISPR

ACACB - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

ACACB - human gene knockout kit via CRISPR

ACACB - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

ACACB - human gene knockout kit via CRISPR

ACACB - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, ACACB (Myc-DDK tagged) - Human acetyl-CoA carboxylase beta (ACACB), 200 uL, >10^7 TU/mL

Lenti ORF particles, ACACB (Myc-DDK tagged) - Human acetyl-CoA carboxylase beta (ACACB), 200 uL, >10^7 TU/mL  
200 µl / €2,280.00
  OriGene Technologies, Inc.

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