Acetylcholine receptor beta subunit antibody

Principal name

Acetylcholine receptor beta subunit antibody

Alternative names for Acetylcholine receptor beta subunit antibody

CHRNB1, ACHRB, CHRNB

SwissProt ID

P04758 (Bovin), P09690 (Mouse), P11230 (Human), P25109 (Rat)

Gene ID

1140 (CHRNB1), 24261 (Chrnb1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine)

Available hosts

Mouse, Rabbit, Goat

Available applications

Frozen Sections (C), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Flow Cytometry (F), Enzyme Immunoassay (E), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of Acetylcholine receptor beta subunit antibody

Neurol nicotinic acetylcholine receptors (ChRs) belong to the superfamily of ligand-gated ion channels and are widely expressed throughout the central and peripheral nervous systems. ChRs play crucial roles in modulating a wide range of higher cognitive functions by mediating presyptic, postsyptic, and extrasyptic sigling.ChRs are formed by the assembly of five transmembrane subunits, selected from a pool of 17 homologous polypeptides (a1-10, Ã?1-4, ?, d, and e). There are many ChR subtypes, each consisting of a specific combition of subunits, which mediate diverse physiological functions. They are widely expressed in the central nervous system, while, in the periphery, they mediate syptic transmission at the neuromuscular junction and ganglia. ChRs are also found in non-neurol/non-muscle cells (keratinocytes, epithelia, macrophages, etc. ). Structurally, all subunits have the following: a conserved large extracellular N-termil domain, 3 conserved transmembrane domains, a variable cytoplasmic loop and a fourth transmembrane domain with a short extracellular C-termil domain. An active ChR is generally a heteropentamer of these various subunits organized around a central pore.While most Ã? subunits are neurol, the Ã?1 subunit forms functiol receptors along with other subunits in the muscle. Ã?1 subunit seems to be involved in myasthenia gravis (MG), an acquired autoimmune disease usually characterized by the presence of circulating autoantibodies that bind to and destroy muscle ChRs.

General readings

Lou XY, Ma JZ, Payne TJ, Beuten J, Crew KM, Li MD.
Gene-based analysis suggests association of the nicotinic acetylcholine receptor beta1 subunit (CHRNB1) and M1 muscarinic acetylcholine receptor (CHRM1) with vulnerability for nicotine dependence.
Hum Genet. 2006 Oct;120(3):381-9. Epub 2006 Jul 28.
PMID: 16874522

14 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Acetylcholine receptor beta subunit antibody

TA305851 (1ug/ml) staining of human cerebellum lysate (35ug protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Bov, Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Acetylcholine receptor beta subunit antibody

Western blot analysis of extracts from HeLa cells, using CHRNB1 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Acetylcholine receptor beta subunit antibody

Western blot analysis of mouse (lanes 1 and 3) and rat (lanes 2 and 4) heart lysates: 1-2. Anti-Nicotinic Acetylcholine Receptor  ß1(extracellular) antibody, (1:500). 3-4. Anti-Nicotinic Acetylcholine Receptor  ß1(extracellular) antibody, preincubated with the control peptide antigen Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

Acetylcholine receptor beta subunit antibody

Western blot analysis of extracts of various cell lines, using CHRNB1 antibody. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Acetylcholine receptor beta subunit antibody

Acetylcholine receptor beta subunit Rabbit Purified Hu, Ms C, E, WB
0.1 mg / €420.00
  Acris Antibodies GmbH

Acetylcholine receptor beta subunit antibody

CHRNB1 polyclonal antibody (A01), Lot # 061103JCS1 Western Blot analysis of CHRNB1 expression in SJCRH30 ( Cat # L027V1 ). Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Acetylcholine receptor beta subunit antibody

Acetylcholine receptor beta subunit Mouse IgG3 4G4 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Acetylcholine receptor beta subunit antibody

CHRNB1 polyclonal antibody ( Cat # PAB11510 ) ( 1 µg/ml ) staining of human cerebellum lysate ( 35 µg protein in RIPA buffer ). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

Acetylcholine receptor beta subunit antibody

Western Blot: ACHR-beta Antibody (EP2067Y) [NB110-62102] - Western blot analysis on  human brain lysate using  anti-ACHR-beta, dilution 1:1000. Rabbit IgG EP2067Y Hu, Ms, Rt F, ICC/IF, WB
0.1 ml / €420.00
  Novus Biologicals Inc.

Acetylcholine receptor beta subunit antibody

Western Blot: CHRNB1 / ACHRB Antibody [NBP1-20900]-(1ug/ml) staining of human cerebellum lysate (35ug protein in RIPA buffer). Goat IgG Aff - Purified Hu E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

Acetylcholine receptor beta subunit antibody

Western Blot: Nicotinic Acetylcholine Receptor beta Antibody (EPR2068) [NBP1-40637] - Western blot analysis on (A) fetal brain, (B) fetal thymus, (C) skeletal muscle and (D) heart lysates using anti-ACHR-beta Rabbit IgG EPR2068 Hu, Ms, Rt F, WB
0.1 ml / €420.00
  Novus Biologicals Inc.

Acetylcholine receptor beta subunit antibody

Immunohistochemistry-Paraffin: Nicotinic Acetylcholine Receptor beta Antibody [NBP1-84478] - Immunohistochemical staining of human liver shows cytoplasmic positivity in hepatocytes. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Acetylcholine receptor beta subunit

Acetylcholine receptor beta subunit Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

Acetylcholine receptor beta subunit

Acetylcholine receptor beta subunit Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

14 Item(s)

per page
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