Acinus / ACIN1 antibody

Principal name

Acinus / ACIN1 antibody

Alternative names for Acinus / ACIN1 antibody

KIAA0670, Apoptotic chromatin condensation inducer in the nucleus

SwissProt ID

Q9JIX8 (Mouse), Q9UKV3 (Human)

Gene ID

22985 (ACIN1), 56215 (Acin1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E), Paraffin Sections (P), Immunoprecipitation (IP)

Background of Acinus / ACIN1 antibody

Chromatin condensation and nuclear fragmentation (CCNF) are the hallmarks of apoptosis. CCNF is triggered by the activation of members of the caspase family, caspase activated DNase (CAD/DFF40), and several novel proteins including AIF and CIDE. A new inducer of chromatin condensation was recently identified and designated Acinus (for apoptotic chromatin condensation inducer in the nucleus). Acinus is cleaved by Caspase 3 and an additional unknown protease generating a small active peptide p17, which causes chromatin condensation in vitro when it is added to purified nuclei. Acinus also induces apoptotic chromatin condensation in cells. Acinus is ubiquitously expressed. Three different spliced forms of Acinus have been identified in human and mouse and designated Acinus L (1341 amino acids), Acinus S (583 amino acids) and Acinus S' (614 amino acids)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Acinus / ACIN1 (AcinusL) (N-term) antibody

Western blot analysis of AcinusL expression in several cell lines using AM26695AF-N. 1; Jurkat, 2; Raji, 3; Hela, 4; HL60, 5; U937, 6; A431, 7; HPB-ALL, 8; WR19L, 9; NIH3T3, 10; L5178Y, 11; CHO Mouse IgG1 3H8 Azide Free Hu IP, WB
0.1 mg / €390.00
  Acris Antibodies GmbH

Acinus / ACIN1 antibody

Human Adrenal (formalin-fixed, paraffin-embedded) stained with ACIN1 antibody AP22851PU-N at 5 µg/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Rabbit Purified Hu E, ICC/IF, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

Acinus / ACIN1 (775-789) antibody

Human Adrenal (formalin-fixed, paraffin-embedded) stained with ACIN1 antibody AP22852PU-N at 5 µg/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Rabbit Purified Hu E, ICC/IF, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

Acinus / ACIN1 antibody

Western blot analysis of Acinus in K562 whole cell lysate with Acinus antibody (CP) at 1 ug/mL. Rabbit IgG Aff - Purified Hu E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Acinus / ACIN1 (C-term) antibody

Western blot analysis of Acinus in K562 whole cell lysate with Acinus antibody at 0.5 ug/mL. Rabbit IgG Aff - Purified Hu E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Acinus / ACIN1 antibody

Western blot analysis of Acinus in K562 whole cell lysate with Acinus antibody (IN) at 1 ug/mL. Rabbit IgG Aff - Purified Hu E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Acinus / ACIN1 antibody

Western blot analysis of acinus in K562 whole cell lysate with acinus antibody at 1 µg/ml. Rabbit IgG Aff - Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Acinus / ACIN1 antibody

Predicted band size: 152 kDa . Positive control: 231 cell lysate. Recommended dilution: 1/500-2000 Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Acinus / ACIN1 antibody

Predicted band size: 152 kDa . Positive control: K562 and 231 cell lysate. Recommended dilution: 1/200-1000 Rabbit IgG Purified Hu, Ms, Rt P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Acinus / ACIN1 antibody

Predicted cell location: Nucleus,Cytoplasm. Positive control: Human breast and esophagus cancer tissue. Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded human breast cancer tissue using ACIN1 antibody at dilution 1/30, on the right is treated with the synthetic peptide. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Acinus / ACIN1 antibody

Predicted cell location: Nucleus,Cytoplasm. Positive control: Human liver and esophagus cancer tissue. Recommended dilution: 1/100-300  The image on the left is immunohistochemistry of paraffin-embedded human liver cancer tissue using ACIN1 antibody at dilution 1/80, on the right is treated with the synthetic peptide. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Acinus / ACIN1 antibody

Western Blot: Acinus Antibody [TA336656] - Western Blot on transfected COS-7 cells at a 1:500 dilution. Rabbit Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Acinus / ACIN1 antibody

Western Blot: Acinus Antibody [TA336657] - Analysis of Acinus in transfected COS-7 cells using TA336657 at 1:500 dilution. TA336657 Recognizes both long and short forms of Acinus protein. Rabbit Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Acinus / ACIN1 antibody

Host: Rabbit; Target Name: Acin1; Sample Tissue: Mouse Brain lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Hu, Ms WB
50 µg / €325.00
  OriGene Technologies, Inc.

Acinus / ACIN1 antibody

Western blot analysis using anti-Acinus (NT) antibody at 1.0 µg/ml on K562 cell lysate. Rabbit IgG Purified Hu WB
0.1 mg / €370.00
  Acris Antibodies GmbH

Acinus / ACIN1 antibody

Western blot analysis using anti-Acinus (CT) antibody at 0.5 µg/ml on K562 cell lysate. Rabbit IgG Purified Hu WB
0.1 mg / €370.00
  Acris Antibodies GmbH

Acinus / ACIN1 antibody

Western blot analysis using anti-Acinus (IN) antibody at 1 µg/ml on K562 cell lysate. Rabbit IgG Purified Hu WB
0.1 mg / €370.00
  Acris Antibodies GmbH

Acinus / ACIN1 antibody

Western blot analysis using anti-Acinus (NP) antibody at 1 µg/ml on K562 cell lysate. Rabbit IgG Purified Hu WB
0.1 mg / €370.00
  Acris Antibodies GmbH

Acinus / ACIN1 antibody

Western Blot analysis of Acinus in K562 whole cell lysate with this antibody Rabbit IgG Purified Hu WB
0.1 mg / €330.00
  Acris Antibodies GmbH

Acinus / ACIN1 antibody

Immunocytochemical staining of K562 erythromyeloblastoid cells with Rabbit anti Human Acinus (AP05825PU-N) Rabbit IgG Purified Hu ICC/IF, WB
0.1 mg / €330.00
  Acris Antibodies GmbH

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