ACOX1 antibody

Principal name

ACOX1 antibody

Alternative names for ACOX1 antibody

AOX, Palmitoyl-CoA oxidase, Straight-chain acyl-CoA oxidase, Peroxisomal acyl-coenzyme A oxidase 1

SwissProt ID

P07872 (Rat), Q15067 (Human), Q3SZP5 (Bovin), Q9R0H0 (Mouse), Q9Z1N0 (Cavpo)

Gene ID

51 (ACOX1), 11430 (Acox1), 50681

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Eq (Equine), Por (Porcine), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Paraffin Sections (P)

Background of ACOX1 antibody

ACOX1 is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids. 
Function: Catalyzes the desaturation of acyl-CoAs to 2-trans- enoyl-CoAs. Isoform 1 shows highest activity against medium-chain fatty acyl-CoAs and activity decreases with increasing chain length. Isoform 2 is active against a much broader range of substrates and shows activity towards very long-chain acyl-CoAs. Isoform 2 is twice as active as isoform 1 against 16-hydroxy- palmitoyl-CoA and is 25% more active against 1,16-hexadecanodioyl- CoA.
Cellular Location: Peroxisome. 
Tissue Location: Widely expressed with highest levels of isoform 1 and isoform 2 detected in testis. Isoform 1 is expressed at higher levels than isoform 2 in liver and kidney while isoform 2 levels are higher in brain, lung, muscle, white adipose tissue and testis. Levels are almost equal in heart.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ACOX1 antibody

  Anti-ACOX1 rabbit polyclonal antibody  
Predicted band size: 74 kDa . Positive control: Mouse stomach, liver and kidney tissue lysate. Recommended dilution: 1/200-1000. (Gel: 8%SDS-PAGE Lane1: Mouse stomach tissue lysate Lane2: Mouse liver tissue lysate Lane3: Mouse kidney tissue lysate Lysates: 40 ug per lane Primary antibody: 1/350 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

ACOX1 antibody

  Anti-ACOX1 Rabbit Polyclonal Antibody  
Predicted cell location: Cytoplasm. Positive control: Human cervical and thyroid cancer tissue. Recommended dilution: 1/50-200  The image on the left is immunohistochemistry of paraffin-embedded human cervical cancer tissue using ACOX1 antibody at dilution 1/40, on the right is treated with the fusion protein. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

ACOX1 antibody

  Rabbit Polyclonal Anti-Paox Antibody  
Host: Rabbit; Target Name: Paox; Sample Tissue: Rat Pancreas lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Eq, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

ACOX1 antibody

Immunohistochemistry analysis in Formalin Fixed and Paraffin Embedded human colon carcinomastained with ACOX1 Monoclonal Antibody Cat.-No AM33416PU-N (Clone 153CT43.1.1) followed by peroxidase conjugation of the secondary antibody and DAB staining. Mouse IgG1 153CT43.1.1 Purified Hu ICC/IF, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

ACOX1 (N-term) antibody

Western blot analysis of anti-ACOX1 Pab (Cat.#AP12247PU-N) in mouse liver lysate. Data is kindly provided by Hye Won Kang and Dr. McGrane at the Univ. of Connecticut (Storrs, CT). Rabbit Ig Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

ACOX1 (C-term) antibody

(LEFT) Western blot analysis of ACOX1 (arrow) using rabbit polyclonal ACOX1 Antibody (C-term) (Cat#AP12248PU-N). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the ACOX1 gene (Lane 2) (Origene Technologies). (RIGHT) Western blot analysis of ACOX1 (arrow) using rabbit polyclonal ACOX1 Antibody (C-term) (Cat#AP12248PU-N). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the ACOX1 gene (Lane 2) (Origene Technologies). Rabbit Ig Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

ACOX1 - human gene knockout kit via CRISPR

ACOX1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

ACOX1 - human gene knockout kit via CRISPR

ACOX1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

ACOX1 - human gene knockout kit via CRISPR

ACOX1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

ACOX1 - human gene knockout kit via CRISPR

ACOX1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Acox1 - mouse gene knockout kit via CRISPR

Acox1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Acox1 - mouse gene knockout kit via CRISPR

Acox1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Acox1 - mouse gene knockout kit via CRISPR

Acox1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Acox1 - mouse gene knockout kit via CRISPR

Acox1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

ACOX1 overexpression lysate

ACOX1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, ACOX1 (mGFP-tagged)-Human acyl-CoA oxidase 1, palmitoyl (ACOX1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, ACOX1 (mGFP-tagged)-Human acyl-CoA oxidase 1, palmitoyl (ACOX1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, ACOX1 (mGFP-tagged)-Human acyl-CoA oxidase 1, palmitoyl (ACOX1), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, ACOX1 (mGFP-tagged)-Human acyl-CoA oxidase 1, palmitoyl (ACOX1), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,330.00
  OriGene Technologies, Inc.

Lenti ORF particles, ACOX1 (mGFP-tagged)-Human acyl-CoA oxidase 1, palmitoyl (ACOX1), transcript variant 3, 200 uL, >10^7 TU/mL

Lenti ORF particles, ACOX1 (mGFP-tagged)-Human acyl-CoA oxidase 1, palmitoyl (ACOX1), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €1,270.00
  OriGene Technologies, Inc.

Lenti ORF particles, ACOX1 (Myc-DDK-tagged)-Human acyl-CoA oxidase 1, palmitoyl (ACOX1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, ACOX1 (Myc-DDK-tagged)-Human acyl-CoA oxidase 1, palmitoyl (ACOX1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Lenti ORF particles, ACOX1 (Myc-DDK-tagged)-Human acyl-CoA oxidase 1, palmitoyl (ACOX1), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, ACOX1 (Myc-DDK-tagged)-Human acyl-CoA oxidase 1, palmitoyl (ACOX1), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,190.00
  OriGene Technologies, Inc.

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