ACP5 / TR-AP antibody

Principal name

ACP5 / TR-AP antibody

Alternative names for ACP5 / TR-AP antibody

Tartrate-resistant acid phosphatase type 5, TRAP5, TRAcP, Tartrate-resistant acid ATPase, Acid phosphatase 5 tartrate resistant

SwissProt ID

O97860 (Rabit), P09889 (Pig), P13686 (Human), P29288 (Rat), Q05117 (Mouse)

Gene ID

54 (ACP5), 11433 (Acp5), 25732

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Sh (Sheep), Ze (Zebrafish)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP)

Background of ACP5 / TR-AP antibody

TRAP 5 (serum band 5 tartrate-resistant acid phosphatase, TRACP 5; EC 3.1.3.2) is a glycoprotein of 35-37 kDa. TRAP 5 belongs to the most abundant enzymes in osteoclasts. It is expressed in certain differentiated cells of the mononuclear phagocyte system, particularly osteoclasts and alveolar macrophages, where it takes an active part in bone resorption process. High blood levels of TRAP 5 are usually associated with active bone remodelling. Increased serum levels are observed during normal bone growth among healthy children. Elevated serum TRAP levels have been detected in diseases characterized by increased bone resorption; Pagets
disease of the bone, hemodialysis, primary hyperparathyroidism, metastatic malignancies involving bone resorption, multiple myeloma and bilaterally ovariectomized women. Post-menopausal women have higher levels of serum than post-menopausal women on estrogen replacement therapy. Therefore specific determination of TRAP 5 activity can be essential for clinical assessment of bone metabolism.

General readings

Baumbach GA, Saunders PT, Bazer FW, et al. Uteroferrin has N-apsaragine-linked high mannose-type oligosaccharaides that contain mannose 6-phosphate. Proc. Natl. Acad. Sci. USA 1984; 81:2985-9.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ACP5 / TR-AP antibody

  Rabbit polyclonal antibody to TRAP (acid phosphatase 5, tartrate resistant)  
Sample(30 ug whole cell lysate). A:A431. B:MOLT4 . 12% SDS PAGE. TA308289 diluted at 1:1000 Rabbit IgG Aff - Purified Hu, Ms P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

ACP5 / TR-AP (C-term) antibody

  Rabbit Polyclonal TRAP Antibody  
Western blot analysis of TRAP in mouse brain tissue lysate with TRAP antibody at 1 ug/mL. Rabbit IgG Aff - Purified Hu, Ms E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ACP5 / TR-AP antibody

  Rabbit anti-ACP5 Polyclonal Antibody  
Western blot analysis of extracts of various cell lines, using ACP5 antibody. Rabbit IgG Purified Hu, Ms, Rt ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ACP5 / TR-AP antibody

  Mouse Monoclonal anti-tartrate-resistant acid phosphatase (TRAcP) Antibody  
Western blot analysis of recombinant human TRACP/PAP/ACP5 protein (lane 1) and PBMC (lane 2) using anti-TRACP antibody, clone 9C5. Mouse IgG2b 9C5 Purified Hu, Ms, Rt IP, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ACP5 / TR-AP antibody

  Rabbit Polyclonal Anti-ACP5 Antibody  
WB Suggested Anti-ACP5 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: THP-1 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Sh, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

ACP5 / TR-AP antibody

  Mouse Monoclonal anti-tartrate-resistant acid phosphatase (TRAcP) Antibody  
Western blot analysis of recombinant human TRACP/PAP/ACP5 protein (lane 1) and PBMC (lane 2) using anti-TRACP antibody, clone 9C5. Mouse 9C5 Purified Hu, Ms, Rt IP, P, WB
25 µg / €248.00
  OriGene Technologies, Inc.

ACP5 / TR-AP antibody

Formalin-Fixed, Paraffin-Embedded Human bone marrow with hairy cell leukemia stained with TRAcP antibody Cat.-No. AM10145SU-N using peroxidase conjugate and DAB chromogen. Note the cytoplasmic staining of leukemia cells. Mouse IgG2b 9C5 Supernatant Hu P
1 ml / €320.00
  Acris Antibodies GmbH

ACP5 / TR-AP antibody

ACP5 / TR-AP Mouse IgG1 TRAP-01 Purified Hu E
0.1 mg / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

ACP5 - human gene knockout kit via CRISPR

ACP5 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

ACP5 - human gene knockout kit via CRISPR

ACP5 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

ACP5 - human gene knockout kit via CRISPR

ACP5 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

ACP5 - human gene knockout kit via CRISPR

ACP5 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Acp5 - mouse gene knockout kit via CRISPR

Acp5 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Acp5 - mouse gene knockout kit via CRISPR

Acp5 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Acp5 - mouse gene knockout kit via CRISPR

Acp5 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Acp5 - mouse gene knockout kit via CRISPR

Acp5 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

ACP5 / TR-AP (transcript variant 4)

  Recombinant protein of human acid phosphatase 5, tartrate resistant (ACP5), transcript variant 4  
ACP5 / TR-AP Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, ACP5 (mGFP-tagged)-Human acid phosphatase 5, tartrate resistant (ACP5), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, ACP5 (mGFP-tagged)-Human acid phosphatase 5, tartrate resistant (ACP5), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €960.00
  OriGene Technologies, Inc.

Lenti ORF particles, ACP5 (mGFP-tagged)-Human acid phosphatase 5, tartrate resistant (ACP5), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, ACP5 (mGFP-tagged)-Human acid phosphatase 5, tartrate resistant (ACP5), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €960.00
  OriGene Technologies, Inc.

Lenti ORF particles, ACP5 (mGFP-tagged)-Human acid phosphatase 5, tartrate resistant (ACP5), transcript variant 3, 200 uL, >10^7 TU/mL

Lenti ORF particles, ACP5 (mGFP-tagged)-Human acid phosphatase 5, tartrate resistant (ACP5), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €960.00
  OriGene Technologies, Inc.

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