ACTA2 / aortic smooth muscle Actin antibody

Principal name

ACTA2 / aortic smooth muscle Actin antibody

Alternative names for ACTA2 / aortic smooth muscle Actin antibody

ACTSA, ACTVS, Alpha-actin-2, Cell growth-inhibiting gene 46 protein

SwissProt ID

P08023 (Chick), P62736 (Human), P62737 (Mouse), P62738 (Rat), P62739 (Bovin), P62740 (Rabit), Q6TH51 (Danre)

Gene ID

59 (ACTA2), 322509 (acta2)

Available reactivities

Bov (Bovine), Chk (Chicken), Hu (Human), Ms (Mouse), Rb (Rabbit), Rt (Rat), Bab (Baboon), Ze (Zebrafish), Mky (Monkey), Por (Porcine), Sh (Sheep), Eq (Equine), Can (Canine), Fe (Feline), GP (Guinea Pig), Gt (Goat)

Available hosts

Mouse, Rabbit, Goat

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F), Paraffin Sections (P), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Frozen Sections (C), Immunoprecipitation (IP), Dot blot (Dot)

Background of ACTA2 / aortic smooth muscle Actin antibody

Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. In vertebrates 3 main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins coexist in most cell types as components of the cytoskeleton and as mediators of internal cell motility.
Actins are highly conserved proteins expressed in all eucaryotic cells. Actin filaments form part of the cytoskeleton and play essential roles in regulating cell shape and movement. Six distinct actin isotypes have been identified in mammalian cells. Each is encoded by a separated gene and is expressed in a developmentally regulated and tissue-specific manner, alpha and beta cytoplasmic actins are expressed in a wide variety of cells; whereas, expression of alpha skeletal, alpha cardiac, alpha vascular, and gamma enteric actins are more restricted to specialized muscle cell type. Smooth muscle alpha actin is of further interest because it is one of a few genes whose expression is relatively restricted to vascular smooth muscle cells. Further more, expression of smooth muscle alpha actin is regulated by hormones, cell proliferation , and altered by pathological conditions including oncogenic transformation and atherosclerosis.

General readings

Reddy S, Ozgur K, Lu M, Chang W, Mohan SR, Kumar CC, Ruley HE.
Structure of the human smooth muscle alpha-actin gene. Analysis of a cDNA and 5' upstream region. J Biol Chem. 1990 Jan 25;265(3):1683-7. PMID: 2295650

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ACTA2 / aortic smooth muscle Actin (N-term) antibody

TA302403 staining (0.3 ug/ml) of Human Duodenum lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence Goat Aff - Purified Can, Hu, Ms, Por, Rt E, ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ACTA2 / aortic smooth muscle Actin antibody

Formalin fixed paraffin embedded human colon stained with Smooth Muscle Actin antibody DM001. Mouse IgG2a 1A4/asm-1 Purified Bov, Chk, Hu, Ms, Rb, Rt P
1 ml / €460.00
  Acris Antibodies GmbH

ACTA2 / aortic smooth muscle Actin antibody

Formalin fixed paraffin embedded human colon stained with Smooth Muscle Actin antibody DM001. Mouse IgG2a 1A4/asm-1 Purified Bov, Chk, Hu, Ms, Rb, Rt P
0.5 ml / €310.00
  Acris Antibodies GmbH

ACTA2 / aortic smooth muscle Actin antibody

Immunofluorescence analysis of NIH/3T3 cells using ACTA2 antibody Cat.-No AM06574SU-N (green). Blue: DRAQ5 fluorescent DNA dye. Mouse IgG1 1H8 Ascites Hu, Mky, Ms, Rt E, F, ICC/IF, WB
0.1 ml / €430.00
  Acris Antibodies GmbH

ACTA2 / aortic smooth muscle Actin antibody

Immunohistochemical analysis of paraffin-embedded liver tissues (left) and lung cancer tissues (right) using ACTA2 antibody Cat.-No AM06575SU-N with DAB staining. Mouse IgG1 4F4 Ascites Hu, Mky E, P, WB
0.1 ml / €430.00
  Acris Antibodies GmbH

ACTA2 / aortic smooth muscle Actin antibody

Immunohistochemical analysis of paraffin-embedded human duodenum tissues (left) and human esophagus tissues (right) using ACTA2 mouse mAb with DAB staining. Mouse IgG1 4A4 Ascites Hu, Mky, Ms, Rt E, ICC/IF, P, WB
0.1 ml / €430.00
  Acris Antibodies GmbH

ACTA2 / aortic smooth muscle Actin antibody

Human Vessels: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG1 1D11-2B9 Purified Hu E, P, WB
50 µg / €530.00
  Acris Antibodies GmbH

ACTA2 / aortic smooth muscle Actin (134-366) antibody

Human Uterus, Myometrium: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Aff - Purified Bov, Hu, Ms, Ze P, WB
50 µl / €470.00
  Acris Antibodies GmbH

ACTA2 / aortic smooth muscle Actin (N-term) antibody

Alpha smooth muscle actin positivity in the vessel walls of submucosa of small intestine tissue, stained with DB 147 monospecific antibody.Kindly performed and provided by Marián Švajdler, MD and Dr. Lucia Fröhlichová, from Louis Pasteur University Hospital Department of Pathology, Košice, Slovak Republic. Rabbit IgG M16-L Aff - Purified Hu P
0.1 ml / €270.00
  DB Biotech, spol. s r.o.

Sample sizes available

ACTA2 / aortic smooth muscle Actin (N-term) antibody

Alpha smooth muscle actin positivity in the vessel walls of submucosa of small intestine tissue, stained with DB 147 monospecific antibody.Kindly performed and provided by Marián Švajdler, MD and Dr. Lucia Fröhlichová, from Louis Pasteur University Hospital Department of Pathology, Košice, Slovak Republic. Rabbit IgG M16-L Aff - Purified Hu P
0.2 ml / €360.00
  DB Biotech, spol. s r.o.

Sample sizes available

ACTA2 / aortic smooth muscle Actin (N-term) antibody

Alpha smooth muscle actin positivity in the vessel walls of submucosa of small intestine tissue, stained with DB 147 monospecific antibody.Kindly performed and provided by Marián Švajdler, MD and Dr. Lucia Fröhlichová, from Louis Pasteur University Hospital Department of Pathology, Košice, Slovak Republic. Rabbit IgG M16-L Aff - Purified Hu P
0.5 ml / €460.00
  DB Biotech, spol. s r.o.

Sample sizes available

ACTA2 / aortic smooth muscle Actin (N-term) antibody

Alpha smooth muscle actin positivity in the vessel walls of submucosa of small intestine tissue, stained with DB 147 monospecific antibody.Kindly performed and provided by Marián Švajdler, MD and Dr. Lucia Fröhlichová, from Louis Pasteur University Hospital Department of Pathology, Košice, Slovak Republic. Rabbit IgG M16-L Aff - Purified Hu P
1 ml / €700.00
  DB Biotech, spol. s r.o.

Sample sizes available

ACTA2 / aortic smooth muscle Actin antibody

Human leiomyosarcoma stained with anti-Actin antibody Mouse IgG1 1A4 Purified Bov, Chk, Hu, Ms, Rb, Rt ICC/IF, P
0.5 ml / €290.00
  Acris Antibodies GmbH

ACTA2 / aortic smooth muscle Actin antibody

Human leiomyosarcoma stained with anti-Actin antibody Mouse IgG1 1A4 Purified Bov, Chk, Hu, Ms, Rb, Rt ICC/IF, P
1 ml / €410.00
  Acris Antibodies GmbH

ACTA2 / aortic smooth muscle Actin antibody

Human leiomyosarcoma stained with anti-Actin antibody Mouse IgG1 1A4 Purified Bov, Chk, Hu, Ms, Rb, Rt P
0.1 ml / €190.00
  Acris Antibodies GmbH

ACTA2 / aortic smooth muscle Actin (N-term) antibody


Human colon stained with anti-SMA antibody
Rabbit IgG SP171 Purified Hu P, WB
0.5 ml / €520.00
  Acris Antibodies GmbH

ACTA2 / aortic smooth muscle Actin (N-term) antibody


Human colon stained with anti-SMA antibody
Rabbit IgG SP171 Purified Hu P, WB
1 ml / €730.00
  Acris Antibodies GmbH

ACTA2 / aortic smooth muscle Actin (N-term) antibody


Human colon stained with anti-SMA antibody
Rabbit IgG SP171 Purified Hu P, WB
0.1 ml / €300.00
  Acris Antibodies GmbH

ACTA2 / aortic smooth muscle Actin antibody

Formalin-paraffin leiomyosarcoma stained with Smooth Muscle Actin Antibody Cat.-No AM50166PU (Clone SPM332). Mouse IgG2a SPM332 Purified Bab, Bov, Can, Chk, Fe, GP, Gt, Hu, Mky, Ms, Por, Rb, Rt, Sh F, ICC/IF, IP, P, WB
0.2 mg / €390.00
  Acris Antibodies GmbH

ACTA2 / aortic smooth muscle Actin antibody

Formalin-paraffin leiomyosarcoma stained with Smooth Muscle Actin Antibody Cat.-No AM50166PU (Clone SPM332). Mouse IgG2a SPM332 Purified Bab, Bov, Can, Chk, Fe, GP, Gt, Hu, Mky, Ms, Por, Rb, Rt, Sh F, ICC/IF, IP, P, WB
0.1 mg / €320.00
  Acris Antibodies GmbH

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