Activin receptor type 2B / ACVR2B antibody

Principal name

Activin receptor type 2B / ACVR2B antibody

Alternative names for Activin receptor type 2B / ACVR2B antibody

ACTR-IIB, ACTRIIB, Activin receptor type IIB

SwissProt ID

P27040 (Mouse), P38445 (Rat), Q13705 (Human)

Gene ID

93 (ACVR2B), 11481 (Acvr2b), 25366

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Por (Porcine), Rt (Rat), Ze (Zebrafish), African clawed frog

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunoprecipitation (IP)

Background of Activin receptor type 2B / ACVR2B antibody

Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. ACVR2B (activin A type IIB receptor) displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Activin receptor type 2B / ACVR2B (N-term) antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

ACVR2B - human gene knockout kit via CRISPR

ACVR2B - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

ACVR2B - human gene knockout kit via CRISPR

ACVR2B - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

ACVR2B - human gene knockout kit via CRISPR

ACVR2B - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

ACVR2B - human gene knockout kit via CRISPR

ACVR2B - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Acvr2b - mouse gene knockout kit via CRISPR

Acvr2b - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Acvr2b - mouse gene knockout kit via CRISPR

Acvr2b - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Acvr2b - mouse gene knockout kit via CRISPR

Acvr2b - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Acvr2b - mouse gene knockout kit via CRISPR

Acvr2b - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Activin receptor type 2B / ACVR2B

  Recombinant protein of human activin A receptor, type IIB (ACVR2B)  
Activin receptor type 2B / ACVR2B Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Activin receptor type 2B / ACVR2B

  Purified recombinant protein of Human activin A receptor, type IIB (ACVR2B)  
Activin receptor type 2B / ACVR2B Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
10 µg / €139.00
  OriGene Technologies, Inc.

Activin receptor type 2B / ACVR2B

  Purified recombinant protein of Human activin A receptor, type IIB (ACVR2B)  
Activin receptor type 2B / ACVR2B Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
50 µg / €139.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

ACVR2B overexpression lysate

ACVR2B overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, ACVR2B (mGFP-tagged) - Human activin A receptor, type IIB (ACVR2B), 200 uL, >10^7 TU/mL

Lenti ORF particles, ACVR2B (mGFP-tagged) - Human activin A receptor, type IIB (ACVR2B), 200 uL, >10^7 TU/mL  
200 µl / €1,140.00
  OriGene Technologies, Inc.

Lenti ORF particles, ACVR2B (Myc-DDK tagged) - Human activin A receptor, type IIB (ACVR2B) , 200 uL, >10^7 TU/mL

Lenti ORF particles, ACVR2B (Myc-DDK tagged) - Human activin A receptor, type IIB (ACVR2B) , 200 uL, >10^7 TU/mL  
200 µl / €1,020.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Acvr2b (GFP-tagged ORF) - Rat activin A receptor, type IIB (Acvr2b), 200 uL, >10^7 TU/mL

Lenti ORF particles, Acvr2b (GFP-tagged ORF) - Rat activin A receptor, type IIB (Acvr2b), 200 uL, >10^7 TU/mL  
200 µl / €1,130.00
  OriGene Technologies, Inc.

Lenti ORF particles, Acvr2b (Myc-DDK-tagged ORF) - Rat activin A receptor, type IIB (Acvr2b), 200 uL, >10^7 TU/mL

Lenti ORF particles, Acvr2b (Myc-DDK-tagged ORF) - Rat activin A receptor, type IIB (Acvr2b), 200 uL, >10^7 TU/mL  
200 µl / €1,016.00
  OriGene Technologies, Inc.

17 Item(s)

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