ACTL7B antibody

Principal name

ACTL7B antibody

Alternative names for ACTL7B antibody

Actin-like protein 7B, Actin-like-7-beta

SwissProt ID

Q32L91 (Bovin), Q4QR76 (Rat), Q9QY83 (Mouse), Q9Y614 (Human)

Gene ID

10880 (ACTL7B), 11471 (Actl7b)

Available reactivities

Hu (Human), Rt (Rat), Ms (Mouse), Bov (Bovine), Can (Canine)

Available hosts

Mouse, Goat, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), EPair for Elisa (EPair), Immunoprecipitation (IP), Paraffin Sections (P)

Background of ACTL7B antibody

ACTL7B is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventiol actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. Based on mutatiol alysis of the ACTL7B gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. Unlike ACTL7A, the ACTL7B gene is expressed predomintly in the testis, however, its exact function is not known.The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventiol actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene (ACTL7B), and related gene, ACTL7A, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutatiol alysis of the ACTL7B gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. Unlike ACTL7A, the ACTL7B gene is expressed predomintly in the testis, however, its exact function is not known.

General readings

Chadwick BP, Mull J, Helbling LA, Gill S, Leyne M, Robbins CM, Pinkett HW, Makalowska I, Maayan C, Blumenfeld A, Axelrod FB, Brownstein M, Gusella JF, Slaugenhaupt SA.
Cloning, mapping, and expression of two novel actin genes, actin-like-7A (ACTL7A) and actin-like-7B (ACTL7B), from the familial dysautonomia candidate region on 9q31.
Genomics. 1999 Jun 15;58(3):302-9.
PMID: 10373328

17 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ACTL7B antibody

  Goat Polyclonal Antibody against ACTL7B  
TA303311 (0.03µg/ml) staining of human testis lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ACTL7B antibody

  Goat Anti-Actin-like 7B (mouse) Antibody  
TA305837 (0.5ug/ml) staining of Rat Testes lysate (35ug protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ACTL7B antibody

  Anti-ACTL7B Rabbit Polyclonal Antibody  
Predicted cell location: Cytoplasm. Positive control: Human colon cancer tissue. Recommended dilution: 1/15-50  The image on the left is immunohistochemistry of paraffin-embedded human colon cancer tissue using ACTL7B antibody at dilution 1/20, on the right is treated with the fusion protein. (Original magnification:x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

ACTL7B antibody

  Rabbit Polyclonal Anti-ACTL7B Antibody  
WB Suggested Anti-ACTL7B Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: Transfected 293T Rabbit IgG Purified Bov, Can, Hu, Ms, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

ACTL7B (N-term) antibody

ACTL7B Antibody (N-term) (Cat. #AP50070PU-N) western blot analysis in NCI-H292 cell line lysates (35µg/lane).This demonstrates the ACTL7B antibody detected the ACTL7B protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

ACTL7B - human gene knockout kit via CRISPR

ACTL7B - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

ACTL7B - human gene knockout kit via CRISPR

ACTL7B - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Actl7b - mouse gene knockout kit via CRISPR

Actl7b - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Actl7b - mouse gene knockout kit via CRISPR

Actl7b - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Actl7b - mouse gene knockout kit via CRISPR

Actl7b - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Actl7b - mouse gene knockout kit via CRISPR

Actl7b - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

ACTL7B

  Recombinant protein of human actin-like 7B (ACTL7B)  
ACTL7B Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

Lysates

Catalog No.    

ACTL7B overexpression lysate

ACTL7B overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, ACTL7B (mGFP-tagged) - Human actin-like 7B (ACTL7B), 200 uL, >10^7 TU/mL

Lenti ORF particles, ACTL7B (mGFP-tagged) - Human actin-like 7B (ACTL7B), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, ACTL7B (Myc-DDK tagged) - Human actin-like 7B (ACTL7B) , 200 uL, >10^7 TU/mL

Lenti ORF particles, ACTL7B (Myc-DDK tagged) - Human actin-like 7B (ACTL7B) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Actl7b (GFP-tagged) - Mouse actin-like 7b (Actl7b), 200 uL, >10^7 TU/mL

Lenti ORF particles, Actl7b (GFP-tagged) - Mouse actin-like 7b (Actl7b), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Actl7b (Myc-DDK-tagged) - Mouse actin-like 7b (Actl7b), 200 uL, >10^7 TU/mL

Lenti ORF particles, Actl7b (Myc-DDK-tagged) - Mouse actin-like 7b (Actl7b), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

17 Item(s)

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