ACVRL1 / ALK1 antibody

Principal name

ACVRL1 / ALK1 antibody

Alternative names for ACVRL1 / ALK1 antibody

ACVRLK1, Activin receptor-like kinase 1, SKR3, TGF-B superfamily receptor type I, Serine/threonine-protein kinase receptor R3, Activin A receptor type II-like 1

SwissProt ID

P37023 (Human), P80203 (Rat), Q61288 (Mouse)

Gene ID

94 (ACVRL1), 11482 (Acvrl1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine), Bov (Bovine), Por (Porcine), Eq (Equine)

Available hosts

Goat, Mouse, Rabbit, Rat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Flow Cytometry (F), Immunoprecipitation (IP), Frozen Sections (C)

Background of ACVRL1 / ALK1 antibody

ACVRL1 is a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. ACVRL1, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2. Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human ACVRL1 with an internal ID of P11975

General readings

Johnson DW et al. Mutations in the activin receptor-like kinase 1 gene in hereditary haemorrhagic telangiectasia type 2. Nat Genet 13:189-95 (1996). PubMed PMID: 8640225

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ACVRL1 / ALK1 antibody

Western blot analysis of extracts from K562 cells, using ACVL1 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

ACVRL1 / ALK1 antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with ACVRL1 polyclonal antibody ( Cat # PAB3475 ) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. HC = hepatocarcinoma. Rabbit Hu, Ms E, ICC/IF, P, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

ACVRL1 / ALK1 (C-term) antibody

Antibody (AP31557PU-N)(2µg/ml) staining of MCF7 lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu E, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

ACVRL1 / ALK1 antibody

WB Suggested Anti-ACVRL1 Antibody Titration: 0.2-1 ug/ml; Positive Control: Jurkat cell lysate Rabbit IgG Purified Can, Eq, Hu, Ms, Por, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

ACVRL1 / ALK1 antibody

Immunohistochemistry analysis of ALK-1 Antibody (Cat.-No AP01172PU-N) in paraffin-embedded human breast carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

ACVRL1 / ALK1 (N-term) antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Purified Hu, Ms ICC/IF, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

ACVRL1 / ALK1 (C-term) antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

ACVRL1 / ALK1 (441-503) antibody

Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Aff - Purified Hu P, WB
50 µl / €470.00
  Acris Antibodies GmbH

ACVRL1 / ALK1 (196-245) antibody

Human Brain Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

ACVRL1 / ALK1 antibody

ACVRL1 / ALK1 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

ACVRL1 / ALK1 antibody

Western Blot analysis of ACVRL1 expression in transfected 293T cell line by ACVRL1 monoclonal antibody (M01), clone 5B1.

Lane 1: ACVRL1 transfected lysate(56.124 KDa).
Lane 2: Non-transfected lysate. Mouse IgG1 5B1 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

ACVRL1 / ALK1 antibody

Western Blot analysis of ACVRL1 expression in transfected 293T cell line by ACVRL1 monoclonal antibody (M02), clone 7H2.

Lane 1: ACVRL1 transfected lysate(56.1 KDa).
Lane 2: Non-transfected lysate. Mouse IgG1 7H2 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

ACVRL1 / ALK1 antibody

ACVRL1 / ALK1 Mouse IgG1 5F2 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

ACVRL1 / ALK1 antibody

Western Blot analysis of ACVRL1 expression in transfected 293T cell line by ACVRL1 monoclonal antibody (M06), clone 2C12.

Lane 1: ACVRL1 transfected lysate(56.1 KDa).
Lane 2: Non-transfected lysate. Mouse IgG2a 2C12 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

ACVRL1 / ALK1 antibody

ACVRL1 / ALK1 Mouse IgG2a 1E7 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

ACVRL1 / ALK1 antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with ACVRL1 polyclonal antibody ( Cat # PAB3476 ) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. HC = hepatocarcinoma. Rabbit Hu E, P, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

ACVRL1 / ALK1 antibody

ACVRL1 / ALK1 Goat Hu E
0.1 mg / €400.00
  Abnova Taiwan Corp.

ACVRL1 / ALK1 antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using ACVL1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
50 µg / €205.00
  Assay Biotech

ACVRL1 / ALK1 antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using ACVL1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 mg / €310.00
  Assay Biotech

ACVRL1 / ALK1 antibody

Human Jurkat; WB Suggested Anti-ACVRL1 Antibody Titration: 0.2-1 ug/ml. Positive Control: Jurkat cell lysate; ACVRL1 antibody - N-terminal region (ARP44199_P050) in Human Jurkat cells using Western Blot Rabbit Aff - Purified Can, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

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