ACVRL1 / ALK1 antibody

Principal name

ACVRL1 / ALK1 antibody

Alternative names for ACVRL1 / ALK1 antibody

ACVRLK1, Activin receptor-like kinase 1, SKR3, TGF-B superfamily receptor type I, Serine/threonine-protein kinase receptor R3, Activin A receptor type II-like 1

SwissProt ID

P37023 (Human), P80203 (Rat), Q61288 (Mouse)

Gene ID

94 (ACVRL1), 11482 (Acvrl1), 25237

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine), Bov (Bovine), Por (Porcine), Eq (Equine)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of ACVRL1 / ALK1 antibody

ACVRL1 is a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. ACVRL1, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2. Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human ACVRL1 with an internal ID of P11975

General readings

Chien CY., et al. (2013) Otolaryngol Head Neck Surg. 148(6):965-973.Yu Q., et al. (2013) PLoS ONE. 8(2):E58031.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ACVRL1 / ALK1 antibody

  Rabbit polyclonal anti-ACVL1 antibody  
Western blot analysis of extracts from K562 cells, using ACVL1 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

ACVRL1 / ALK1 (C-term) antibody

Antibody (AP31557PU-N)(2µg/ml) staining of MCF7 lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu E, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

ACVRL1 / ALK1 antibody

  Rabbit Polyclonal Anti-ACVRL1 Antibody  
WB Suggested Anti-ACVRL1 Antibody Titration: 0.2-1 ug/ml; Positive Control: Jurkat cell lysate Rabbit IgG Purified Can, Eq, Hu, Ms, Por, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

ACVRL1 / ALK1 antibody

Immunohistochemistry analysis of ALK-1 Antibody (Cat.-No AP01172PU-N) in paraffin-embedded human breast carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

ACVRL1 / ALK1 (N-term) antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Purified Hu, Ms ICC/IF, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

ACVRL1 / ALK1 (C-term) antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

ACVRL1 / ALK1 (441-503) antibody

Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Aff - Purified Hu P, WB
50 µl / €470.00
  Acris Antibodies GmbH

ACVRL1 / ALK1 (196-245) antibody

Human Brain Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

ACVRL1 / ALK1 antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using ACVL1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
50 µg / €230.00
  Assay Biotech

ACVRL1 / ALK1 antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using ACVL1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

ACVRL1 - human gene knockout kit via CRISPR

ACVRL1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

ACVRL1 - human gene knockout kit via CRISPR

ACVRL1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

ACVRL1 - human gene knockout kit via CRISPR

ACVRL1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

ACVRL1 - human gene knockout kit via CRISPR

ACVRL1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Acvrl1 - mouse gene knockout kit via CRISPR

Acvrl1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Acvrl1 - mouse gene knockout kit via CRISPR

Acvrl1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Acvrl1 - mouse gene knockout kit via CRISPR

Acvrl1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Acvrl1 - mouse gene knockout kit via CRISPR

Acvrl1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

ACVRL1 / ALK1 (transcript variant 2)

  Recombinant protein of human activin A receptor type II-like 1 (ACVRL1), transcript variant 2  
ACVRL1 / ALK1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

ACVRL1 / ALK1 (22-118, His-tag)

ACVRL1 / ALK1 Human Purified > 95 % by SDS - PAGE Insect cells
0.25 mg / €940.00
  Acris Antibodies GmbH

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