ADAM12 / MLTN antibody

Principal name

ADAM12 / MLTN antibody

Alternative names for ADAM12 / MLTN antibody

Meltrin alpha, Disintegrin and metalloproteinase domain-containing protein 12

SwissProt ID

O43184 (Human), Q61824 (Mouse)

Gene ID

8038 (ADAM12), 11489 (Adam12)

Available reactivities

Hu (Human), Bov (Bovine), Chk (Chicken), Ms (Mouse), Rt (Rat), Por (Porcine), Can (Canine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Mouse, Goat, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P), EPair for Elisa (EPair)

Background of ADAM12 / MLTN antibody

ADAM12 is a member of the ADAM (a disintegrin and metalloprotease like domain) family. Two forms of ADAM12 have been described: ADAM12S and ADAM12L (short and long forms). The short form is a soluble form lacking the transmembrane and cytoplasmic domains. The short form of ADAM12 was reported to provoke myogenesis, and the lack of cytoplasmic domain suggests different regulation pathways (although both forms can be expressed in the same tissue). Other papers investigated the SH3 ligand domains in the cytoplasmic portion of ADAM12, demonstrating regulation routes for ADAM12 via Src and Src tyrosine kinase. ADAM12 is primarily expressed in muscle and bone (although placenta, osteoblasts, and many tumor cell lines also express ADAM12). ADAM12 supports cell adhesion by acting as a cell attachment molecule and binding integrins through the cysteine rich domain. A marker of skeletal muscle regeneration, it has been implicated in myoblast differentiation and fusion. ADAM12 contains the canonical HExxHxxxxxH zinc metalloproteinase motif. Full length ADAM12 (909 amino acids) has a predicted mass of 99.5 kDa, but due to glycosylation and cyteine rich regions, the reduced protein migrates to 114 kDa (unprocessed) and 84 kDa (processed). The soluble form of ADAM12 (738 amino acids, predicted mass of 80.5 kDa) is seen as a 92 kDa zymogen and 68 kDa furin processed form.

17 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ADAM12 / MLTN (N-term) antibody

  Goat Polyclonal Antibody against ADAM12  
TA302969 staining (0.1µg/ml) of human heart lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. Goat Aff - Purified Hu P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ADAM12 / MLTN antibody

  Anti-ADAM12 Rabbit Polyclonal Antibody  
Predicted cell location: Cytoplasm,Nucleus. Positive control: Human breast and colon cancer tissue. Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded human breast cancer tissue using ADAM12 antibody at dilution 1/30, on the right is treated with the synthetic peptide. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

ADAM12 / MLTN (225-239) antibody

  Goat Anti-ADAM12 (aa225-239) Antibody  
TA326752 (0.3µg/ml) staining of Mouse Heart lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Hu, Ms, Por, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ADAM12 / MLTN antibody

  Rabbit Polyclonal Anti-ADAM12 Antibody  
WB Suggested Anti-ADAM12 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: Human Placenta Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

ADAM12 / MLTN antibody

  Rabbit polyclonal anti-ADAM12 antibody  
ADAM12 / MLTN Rabbit IgG Purified Hu, Ms WB
100 µl / €325.00
  OriGene Technologies, Inc.

ADAM12 / MLTN (N-term) antibody

Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE) Goat Aff - Purified Hu E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

ADAM12 - human gene knockout kit via CRISPR

ADAM12 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

ADAM12 - human gene knockout kit via CRISPR

ADAM12 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

ADAM12 - human gene knockout kit via CRISPR

ADAM12 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

ELISA Kits

Catalog No.    

Human ADAM12 ELISA Kit

Human ADAM12 ELISA Kit  
1 kit / €389.00
  OriGene Technologies, Inc.

Mouse ADAM12 ELISA Kit

Mouse ADAM12 ELISA Kit  
1 kit / €389.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, ADAM12 (mGFP-tagged) - Human ADAM metallopeptidase domain 12 (ADAM12), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, ADAM12 (mGFP-tagged) - Human ADAM metallopeptidase domain 12 (ADAM12), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,900.00
  OriGene Technologies, Inc.

Lenti ORF particles, ADAM12 (mGFP-tagged)-Human ADAM metallopeptidase domain 12 (ADAM12), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, ADAM12 (mGFP-tagged)-Human ADAM metallopeptidase domain 12 (ADAM12), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,620.00
  OriGene Technologies, Inc.

Lenti ORF particles, ADAM12 (Myc-DDK tagged) - Human ADAM metallopeptidase domain 12 (ADAM12), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, ADAM12 (Myc-DDK tagged) - Human ADAM metallopeptidase domain 12 (ADAM12), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €1,710.00
  OriGene Technologies, Inc.

Lenti ORF particles, ADAM12 (Myc-DDK-tagged)-Human ADAM metallopeptidase domain 12 (ADAM12), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, ADAM12 (Myc-DDK-tagged)-Human ADAM metallopeptidase domain 12 (ADAM12), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,460.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Adam12 (GFP-tagged) - Mouse a disintegrin and metallopeptidase domain 12 (meltrin alpha) (Adam12), 200 uL, >10^7 TU/mL

Lenti ORF particles, Adam12 (GFP-tagged) - Mouse a disintegrin and metallopeptidase domain 12 (meltrin alpha) (Adam12), 200 uL, >10^7 TU/mL  
200 µl / €1,650.00
  OriGene Technologies, Inc.

Lenti ORF particles, Adam12 (Myc-DDK-tagged) - Mouse a disintegrin and metallopeptidase domain 12 (meltrin alpha) (Adam12), 200 uL, >10^7 TU/mL

Lenti ORF particles, Adam12 (Myc-DDK-tagged) - Mouse a disintegrin and metallopeptidase domain 12 (meltrin alpha) (Adam12), 200 uL, >10^7 TU/mL  
200 µl / €1,480.00
  OriGene Technologies, Inc.

17 Item(s)

per page
  • LinkedIn