ADAM15 / MDC15 antibody

Principal name

ADAM15 / MDC15 antibody

Alternative names for ADAM15 / MDC15 antibody

Metargidin, Disintegrin and metalloproteinase domain-containing protein 15, Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 15, Metalloprotease RGD disintegrin protein

SwissProt ID

O88839 (Mouse), Q13444 (Human), Q9QYV0 (Rat)

Gene ID

8751 (ADAM15), 11490 (Adam15)

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Rt (Rat), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Mouse, Rabbit, Rat

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Flow Cytometry (F)

Background of ADAM15 / MDC15 antibody

ADAM15 is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling.The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.

General readings

Zhong,J.L., (2008) Mol. Cancer Res. 6 (3), 383-394

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ADAM15 / MDC15 (1-225) antibody

Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Aff - Purified Hu, Ms P, WB
50 µl / €470.00
  Acris Antibodies GmbH

ADAM15 / MDC15 antibody

Western blot analysis of human fetal liver lysates with anti-ADAM15 antibody (diluted at 1:1000). The antibody identified a band of approximately 90kDa furin processed forms of ADAM15 and a 55kDa cleaved products in human fetal lier tissue lysates. The antibody also recognized a fainter band of ~110kDa (zymogen). Rabbit Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

ADAM15 / MDC15 antibody

Predicted band size: 93 kDa . Positive control: Human liver cancer tissue, NIH/3T3 and Jurkat cell lysate. Recommended dilution: 1/200-1000. (Gel: 8%SDS-PAGE Lane1: Human liver cancer tissue lysate Lane2: NIH/3T3 cell lysate Lane3: Jurkat cell lysate Lysates: 40 ug per lane Primary antibody: 1/300 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 5 minutes) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

ADAM15 / MDC15 antibody

Predicted cell location: Cytoplasm. Positive control: Human brain and lung cancer tissue. Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded human brain tissue using ADAM15 antibody at dilution 1/35, on the right is treated with the fusion protein. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

ADAM15 / MDC15 antibody

WB Suggested Anti-ADAM15 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: Human brain Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

ADAM15 / MDC15 antibody

Western Blot analysis of ADAM15 expression in transfected 293T cell line (H00008751-T01) by ADAM15 MaxPab polyclonal antibody.

Lane 1: ADAM15 transfected lysate(84.92 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

ADAM15 / MDC15 antibody

Mouse, Rat; rat and mouse brain; ADAM15 antibody - middle region (ARP46370_P050) in Mouse, Rat cells using Immunohistochemistry Rabbit Aff - Purified Bov, Hu, Ms, Rt P, WB
50 µg / €350.00
  AVIVA Systems Biology

ADAM15 / MDC15 antibody

Western Blot: ADAM15 Antibody [NBP1-31526] - Western blot analysis of NBP1-31526 on Hep G2, with 7.5% SDS PAGE, diluted at 1:1000. Rabbit IgG Hu P, WB
0.1 ml / €420.00
  Novus Biologicals Inc.

ADAM15 / MDC15 antibody

Immunohistochemistry-Paraffin: ADAM15 Antibody [NBP1-82788] - Immunohistochemistry-Paraffin: ADAM15 Antibody [NBP1-82788] Immunohistochemical staining of human spleen shows strong cytoplasmic positivity in cells in red pulp. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

ADAM15 / MDC15

ADAM15 / MDC15 Human Purified
10 µg / €380.00
  Abnova Taiwan Corp.

ADAM15 / MDC15

ADAM15 / MDC15 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

ADAM15 / MDC15

ADAM15 / MDC15 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

ADAM15 / MDC15

ADAM15 / MDC15 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

ADAM15 / MDC15

ADAM15 / MDC15 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

ADAM15 293T Cell Transient Overexpression Lysate(Denatured)

ADAM15 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

ADAM15 overexpression lysate

ADAM15 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

16 Item(s)

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