ADAM20 antibody

Principal name

ADAM20 antibody

Alternative names for ADAM20 antibody

Disintegrin and metalloproteinase domain-containing protein 20

SwissProt ID

O43506 (Human)

Gene ID

8748 (ADAM20)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Mky (Monkey)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Flow Cytometry (F)

Background of ADAM20 antibody

ADAM20 was first cloned from a human testis library as a protein with homology to the fertilins (ADAMs 1, 2). ADAM20 message was seen predominantly in testis, but also at lower levels in placenta and B-cells. ADAM20 is closely related to ADAM21 (61% identical), ADAM29 (52% identical), and the testases (49-46% identical). ADAM20 contains the canonical HExxHxxxxxH zinc metalloproteinase motif, and the initial partial sequence of ADAM21 contained a non-functional catalytic site, making it tempting to speculate that ADAM20 and ADAM21 are orthologs to ADAMs 1&2. Later, a full-length ADAM21 sequence demonstrated a functional catalytic domain, but it may still be that the catalytically dead form of ADAM21 is expressed and functions as a fettilin. A member of the metalloproteinase family containing disintegrin-like domains (ADAMs) the function of ADAM20 is still poorly understood. Other ADAMs family members (ADAM10, ADAM17) have been more thoroughly studied, and are known to play key roles in inflammation, growth factor maturation and release, and a wide range of other functions. The full length ADAM20 sequence codes for a 726 amino acid protein, with a predicted mass is 81.711 kD. The sequence containing a Type-I transmembrane domain, metalloproteinase domain, cystein-rich domain, and a short cytoplasmic domain. Unlike many of the other ADAMs proteases, ADAM20 does not appear to contain a furin cleavage site.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ADAM20 antibody

Western blot analysis of human fetal testis lysates with anti-ADAM20 antibody (diluted at 1:500). This antibody identified a band of ~68kDa. Rabbit Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

ADAM20 antibody

Predicted cell location: Cytoplasm. Positive control: Human liver cancer tissue. Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded human liver cancer tissue using ADAM20 antibody at dilution 1/50, on the right is treated with the fusion protein. (Original magnification:x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

ADAM20 antibody

Predicted band size: 82 kDa . Positive control: PC3 and hela cell lysate. Recommended dilution: 1/100-500. (Gel: 8%SDS-PAGE Lane1: PC3 cell lysate Lane2: Hela cell lysate Lysates: 40 ug per lane Primary antibody: 1/100 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 10 seconds) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

ADAM20 antibody

Anti-ADAM20 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Purified Hu, Mky P
50 µg / €379.00
  OriGene Technologies, Inc.

ADAM20 antibody

Anti-ADAM20 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Purified Hu, Mky P
50 µg / €379.00
  OriGene Technologies, Inc.

ADAM20 antibody

Anti-ADAM20 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Purified Hu P
50 µg / €379.00
  OriGene Technologies, Inc.

ADAM20 antibody

Anti-ADAM20 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Purified Hu P
50 µg / €379.00
  OriGene Technologies, Inc.

ADAM20 antibody

ADAM20 polyclonal antibody (A01), Lot # 060613JCS1 Western Blot analysis of ADAM20 expression in Hela NE ( Cat # L013V3 ). Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

ADAM20 antibody

ADAM20 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

ADAM20 antibody

Detection limit for recombinant GST tagged ADAM20 is approximately 1ng/ml as a capture antibody. Mouse IgG2b 4B10 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

ADAM20

ADAM20 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

ADAM20

ADAM20 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

ADAM20 overexpression lysate

ADAM20 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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