Adapter protein CIKS antibody

Principal name

Adapter protein CIKS antibody

Alternative names for Adapter protein CIKS antibody

TRAF3IP2, C6orf4, C6orf5, C6orf6, ACT1, Connection to IKK and SAPK/JNK, TRAF3-interacting protein 2, Nuclear factor NF-kappa-B activator 1

SwissProt ID

O43734 (Human)

Gene ID

10758 (TRAF3IP2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Eq (Equine), GP (Guinea Pig)

Available hosts

Rabbit, Mouse, Goat

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunoprecipitation (IP)

Background of Adapter protein CIKS antibody

NF-kB (nuclear factor kB) is sequestered in the cytoplasm by IkB family of inhibitory proteins that mask the nuclear localization sigl of NF-kB thereby preventing translocation of NF-kB to the nucleus (1). Exterl stimuli such as tumor necrosis factor or other cytokines, such as IL-1 results in phosphorylation and degradation of IkB releasing NF-kB dimers. NF-kB dimer subsequently translocates to the nucleus and activates target genes (2). Recently, Li et al. (3) have isolated a cD coding for a protein med Act1 (NF- B activator 1). Act1/CIKS cD codes for a protein containing 574 aa with a predicated molecular mass of 60 kDa. Act1/CIKS protein contains a helix-loop-helix domain in its N-termil portion and a coiled-coil structure at the C terminus. Act1 lacks any catalytic domain, however, it activates IKK through the helix-loop-helix domain. The activation of NF- B by Act1 appears to be through the NIK-IKK complex, because a NIK domint-negative mutant protein inhibited Act1-induced NF- B activation. IL-1 responsive pathway is also necessary for Act1 function. Act1 mR is expressed in a variety of tissues, with high level in thymus, kidney and placenta; moderate level in heart, skeletal muscle, colon, liver, lung and small intestine; and at a very low level in brain, spleen, and peripheral blood leukocytes.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Adapter protein CIKS antibody

Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG2a 4A3 Purified Hu E, ICC/IF, P, WB
50 µg / €530.00
  Acris Antibodies GmbH

Adapter protein CIKS antibody

AP32701PU-N (2 µg/ml) staining of MCF7 lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Adapter protein CIKS antibody

  Rabbit Polyclonal CIKS Antibody  
Western blot analysis of CIKS expression in human placenta tissue lysate with CIKS antibody at 1 ug /ml. Rabbit IgG Purified Hu ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Adapter protein CIKS antibody

  Rabbit Polyclonal CIKS Antibody  
Western blot analysis of CIKS expression in human lung (lane A) and placenta (lane B) tissue lysates with CIKS antibody at 1 ug /ml. Rabbit IgG Purified Hu ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Adapter protein CIKS antibody

  Anti-TRAF3IP2 Rabbit Polyclonal Antibody  
Predicted band size: 65 kDa . Positive control: Jurkat cell lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lysate: 40 ug per lane Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 40 seconds) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Adapter protein CIKS antibody

  Anti-TRAF3IP2 Rabbit Polyclonal Antibody  
Predicted band size: 65 kDa . Positive control: Jurkat cell lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lysate: 40 ug per lane Primary antibody: 1/400 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 20 seconds) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Adapter protein CIKS antibody

  Rabbit Polyclonal TRAF3IP2 Antibody  
Western Blot: TRAF3IP2 Antibody [TA336472] - Analysis of ACT1 in human kidney lysate in the A) absence and B) presence of immunizing peptide using ACT1 antibody at 2 ug/ml. Rabbit Purified Hu, Ms WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Adapter protein CIKS antibody

  Rabbit Polyclonal Anti-TRAF3IP2 Antibody  
WB Suggested Anti-TRAF3IP2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: Hela cell lysate Rabbit IgG Purified Eq, GP, Hu, Ms, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

Adapter protein CIKS (2-15) antibody

Small intestine: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit Aff - Purified Hu P, WB
50 µg / €470.00
  Acris Antibodies GmbH

Adapter protein CIKS antibody

Western blot analysis of CIKS expression in human placenta tissue lysate with SP1315P. Rabbit Aff - Purified Hu WB
0.1 mg / €330.00
  Acris Antibodies GmbH

Adapter protein CIKS (N-term) antibody

Western blot analysis of CIKS expression in human lung (lane A) and placenta (lane B) tissue lysates with SP1316P. Rabbit Aff - Purified Hu WB
0.1 mg / €320.00
  Acris Antibodies GmbH

Adapter protein CIKS (N-term) antibody

Western blot analysis of CIKS expression in human lung (lane A) and placenta (lane B) tissue lysates with SP1316P. Rabbit IgG Aff - Purified Hu WB
50 µg / €280.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

TRAF3IP2 - human gene knockout kit via CRISPR

TRAF3IP2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

TRAF3IP2 overexpression lysate

TRAF3IP2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, TRAF3IP2 (mGFP-tagged) - Human TRAF3 interacting protein 2 (TRAF3IP2), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, TRAF3IP2 (mGFP-tagged) - Human TRAF3 interacting protein 2 (TRAF3IP2), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,340.00
  OriGene Technologies, Inc.

Lenti ORF particles, TRAF3IP2 (mGFP-tagged) - Human TRAF3 interacting protein 2 (TRAF3IP2), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, TRAF3IP2 (mGFP-tagged) - Human TRAF3 interacting protein 2 (TRAF3IP2), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, TRAF3IP2 (mGFP-tagged)-Human TRAF3 interacting protein 2 (TRAF3IP2), transcript variant 3, 200 uL, >10^7 TU/mL

Lenti ORF particles, TRAF3IP2 (mGFP-tagged)-Human TRAF3 interacting protein 2 (TRAF3IP2), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, TRAF3IP2 (mGFP-tagged)-Human TRAF3 interacting protein 2 (TRAF3IP2), transcript variant 5, 200 uL, >10^7 TU/mL

Lenti ORF particles, TRAF3IP2 (mGFP-tagged)-Human TRAF3 interacting protein 2 (TRAF3IP2), transcript variant 5, 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, TRAF3IP2 (Myc-DDK tagged) - Human TRAF3 interacting protein 2 (TRAF3IP2), transcript variant 1 , 200 uL, >10^7 TU/mL

Lenti ORF particles, TRAF3IP2 (Myc-DDK tagged) - Human TRAF3 interacting protein 2 (TRAF3IP2), transcript variant 1 , 200 uL, >10^7 TU/mL  
200 µl / €1,200.00
  OriGene Technologies, Inc.

Lenti ORF particles, TRAF3IP2 (Myc-DDK tagged) - Human TRAF3 interacting protein 2 (TRAF3IP2), transcript variant 2 , 200 uL, >10^7 TU/mL

Lenti ORF particles, TRAF3IP2 (Myc-DDK tagged) - Human TRAF3 interacting protein 2 (TRAF3IP2), transcript variant 2 , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

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