ADARB1 / ADAR2 antibody

Principal name

ADARB1 / ADAR2 antibody

Alternative names for ADARB1 / ADAR2 antibody

DRADA2, RED1, RNA-editing enzyme 1, dsRNA adenosine deaminase, RNA-editing deaminase 1, Double-stranded RNA-specific editase 1

SwissProt ID

P51400 (Rat), P78563 (Human), Q91ZS8 (Mouse)

Gene ID

25367 (Adarb1), 104 (ADARB1), 520865 (AASS)

Available reactivities

Rt (Rat), Hu (Human), Ms (Mouse), Can (Canine), Chk (Chicken), Ze (Zebrafish), African clawed frog, Bov (Bovine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Sheep, Rabbit, Mouse

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), ELISA (detection) (E(detection))

Background of ADARB1 / ADAR2 antibody

ADAR2, also designated adenosine deaminase, RNA-specific (RED1), RNA-editing enzyme 1, DRABA2, DRADA2, ADAR2alpha-L1, ADAR2alpha-L2 and ADAR2alpha-L3, mediates RNA editing by destabilizing RNA through deamination of adenosine to inosine. ADAR2 is responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. It can modify its own pre-mRNA and generate new splice sites. Translocation of endogenous ADAR2 from the nucleolus to the nucleoplasm results in increased editing of endogenous ADAR2 substrates. Alternative splicing of this gene results in several transcript variants that may influence RNA editing. RNA editing involves the deamination of adenosines at specific sites, the result of which can be a change in the amino acid sequence of the protein so that it differs from that predicted by the sequence of the DNA.

General readings

1. Wang AL  et al. Down-regulation of the RNA editing enzyme ADAR2 contributes to RGC death in a mouse model of glaucoma. PLoS One 9:e91288 (2014). IHC-P ; Mouse .

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ADARB1 / ADAR2 antibody

Immunofluorescence staining of mouse anterior horns of spinal cord at 6 months, 15 months and 26 months of age. Antibody used at 1/100 dilution and visualized using Donkey anti-Sheep conjugated to Alexa 555 Dye (red color). The blue color is a fluorescent nuclear probe, TOPRO3. (Image modified from original in citation 1) Sheep IgG Aff - Purified Rt ICC/IF, WB
50 µg / €360.00
  Acris Antibodies GmbH

ADARB1 / ADAR2 antibody

Immunofluorescence of purified MaxPab antibody to ADARB1 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Serum Hu E(detection), ICC/IF, WB
50 µl / €370.00
  Abnova Taiwan Corp.

ADARB1 / ADAR2 antibody

Immunofluorescence of purified MaxPab antibody to ADARB1 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

ADARB1 / ADAR2 antibody

Immunofluorescence of purified MaxPab antibody to ADARB1 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

ADARB1 / ADAR2 antibody

Western blot analysis of extracts from HepG2 cells, using ADARB1 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

ADARB1 / ADAR2 antibody

ADARB1 antibody - N-terminal region validated by WB using Mouse brains at 1: 1000. Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

ADARB1 / ADAR2 antibody

WB Suggested Anti-ADARB1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: Transfected 293T Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

ADARB1 / ADAR2 antibody

Western blot (WB) analysis of ADAR2 antibody (Cat.-No.: AP06707PU-N) at 1/500 dilution Lane1:HepG2 whole cell lysate Lane2:MCF-7 whole cell lysate Lane3:Mouse brain tissue lysate Lane4:Rat brain tissue lysate Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

ADARB1 / ADAR2 antibody

Western blot of crude rat brain nuclear exxtract using Adarb1 polyclonal antibody ( Cat # PAB10359 ). Sheep Purified Rt WB
50 µg / €400.00
  Abnova Taiwan Corp.

ADARB1 / ADAR2 antibody

Western blot analysis of extracts from HepG2 cells, using ADARB1 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
50 µg / €205.00
  Assay Biotech

ADARB1 / ADAR2 antibody

Western blot analysis of extracts from HepG2 cells, using ADARB1 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €310.00
  Assay Biotech

ADARB1 / ADAR2 antibody

Mouse brains; ADARB1 antibody - N-terminal region (ARP40342_T100) validated by WB using Mouse brains at 1:1000.; ADARB1 antibody - N-terminal region (ARP40342_T100) in Mouse brains cells using Western Blot Rabbit Aff - Purified African clawed frog, Can, Chk, Hu, Ms, Rt, Ze WB
0.1 mg / €310.00
  AVIVA Systems Biology

ADARB1 / ADAR2 antibody

Transfected 293T; WB Suggested Anti-ADARB1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: Transfected 293T; ADARB1 antibody - N-terminal region (ARP40343_P050) in Transfected 293T cells using Western Blot Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

ADARB1 / ADAR2 antibody

Immunohistochemical analysis of ADAR2 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Chk, Hu, Ms, Rt, Ze ICC/IF, P, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

ADARB1 / ADAR2 antibody

Immunohistochemical analysis of ADAR2 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Chk, Hu, Ms, Rt, Ze ICC/IF, P, WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

ADARB1 / ADAR2 antibody

Immunohistochemical analysis of ADAR2 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Chk, Hu, Ms, Rt, Ze ICC/IF, P, WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

ADARB1 / ADAR2 antibody

ADARB1 / ADAR2 Rabbit IgG Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €420.00
  Novus Biologicals Inc.

ADARB1 / ADAR2 antibody

ADARB1 / ADAR2 Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

ADARB1 / ADAR2 antibody

ADARB1 / ADAR2 Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
50 µg / €290.00
  Novus Biologicals Inc.

ADARB1 / ADAR2 antibody

Immunohistochemistry-Paraffin: RED1 Antibody [NBP1-90240] - Immunohistochemical staining of human kidney shows strong cytoplasmic positivity in cells in tubules. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

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