Adenosine receptor A2b antibody

Principal name

Adenosine receptor A2b antibody

Alternative names for Adenosine receptor A2b antibody

ADORA2B

SwissProt ID

P29275 (Human), P29276 (Rat), Q1LZD0 (Bovin), Q60614 (Mouse), Q6W3F4 (Canfa)

Gene ID

136 (ADORA2B), 29316 (Adora2b)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Eq (Equine), Mky (Monkey), Can (Canine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Goat, Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of Adenosine receptor A2b antibody

Adenosine is an endogenous nucleoside generated locally in tissues under conditions of hypoxia, ischemia, or inflammation. It modulates a variety of physiological functions in many tissues including brain and heart. Adenosine exerts its action via four specific adenosine receptors (also med P1 purinergic receptors): A1-Adenosine Receptor (A1AR), A2A-Adenosine Receptor (A2AAR), A2B-Adenosine Receptor (A2BAR), and A3-Adenosine Receptor (A3AR). All are integral membrane proteins and members of the G Protein-Coupled Receptor superfamily. They share a common structure of seven putative transmembrane domains, an extracellular amino terminus, a cytoplasmic carboxyl terminus, and a third intracellular loop that is important in binding G proteins. The various adenosine receptors can be distinguished on the basis of their distinct molecular structures, distinct tissue distributions, and differential selectivity for adenosine alogs. The A2 Adenosine receptor subtype was subdivided according to affinity for adenosine; A2AAR has high affinity and A2BAR has low affinity. A2BAR is expressed in mast cells, neutrophils, monocytes, macrophages, dendritic cells, T cells, bronchial epithelium, intestil epithelium, smooth muscle, brain, and other cells. In intestil epithelia, A2BAR was found to be the major adenosine receptor subtype expressed and is thought to be involved in diarrheal diseases. It is also believed to be involved in the pathogenesis of chronic airway inflammatory diseases. Thus, antagonists of A2BAR might be effective for the treatment of inflammatory gastrointestil tract disorders as well as asthma and chronic obstructive pulmory disease.

General readings

1. Bazzichi L, Trincavelli L, Rossi A, De Feo F, Lucacchini A, Bombardieri S, Martini C. A2B adenosine receptor activity is reduced in neutrophils from patients with systemic sclerosis. Arthritis Res Ther. 2005;7(2):R189-95. Epub 2004 Dec 10.
PMID: 15743465

17 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Adenosine receptor A2b (C-term) antibody

  Goat Anti-Adenosine A2b Receptor Antibody  
TA305620 (2µg/ml) staining of paraffin embedded Human Kidney. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining. Goat Aff - Purified Hu E, P
0.1 mg / €325.00
  OriGene Technologies, Inc.

Adenosine receptor A2b antibody

  Rabbit Polyclonal Anti-A2B Adenosine Receptor (extracellular)  
Western blot analysis of HL-60 (lanes 1 and 2) cell line, rat brain (lanes 3 and 4) and mouse brain (lanes 5 and 6) lysates: 1,3,5. Anti-A2B Adenosine Receptor (extracellular) antibody, (1:200). 2,4,6. Anti-A2B Adenosine Receptor (extracellular) antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt P, WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

Adenosine receptor A2b antibody

  Rabbit Polyclonal Anti-ADORA2B Antibody (Internal)  
Anti-Adenosine A2b Receptor antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Purified Eq, Hu, Mky P
50 µg / €400.00
  OriGene Technologies, Inc.

Adenosine receptor A2b antibody

  Rabbit Polyclonal Anti-ADORA2B Antibody  
WB Suggested Anti-ADORA2B Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: 293T cell lysate Rabbit IgG Purified Can, Eq, GP, Hu, Por, Rb WB
50 µg / €325.00
  OriGene Technologies, Inc.

Adenosine receptor A2b antibody

  Rabbit Polyclonal Anti-ADORA2B Antibody  
Western blot analysis of ADORA2B in mouse colon tissue lysate with ADORA2B antibody at (A) 0.5 and (B) 1 ug/mL. Rabbit IgG Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Adenosine receptor A2b antibody

Western blot analysis of Adenosine A2B-R Antibody (Cat.-No AP01260PU-N) in extracts from J Jurkat cells. Rabbit Aff - Purified Hu E, ICC/IF, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Adenosine receptor A2b antibody

Immunofluorescence analysis of LOVO cells, using ADORA2B Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF, WB
50 µg / €230.00
  Assay Biotech

Adenosine receptor A2b antibody

Immunofluorescence analysis of LOVO cells, using ADORA2B Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

ADORA2B - human gene knockout kit via CRISPR

ADORA2B - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

ADORA2B - human gene knockout kit via CRISPR

ADORA2B - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

ADORA2B - human gene knockout kit via CRISPR

ADORA2B - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

ADORA2B - human gene knockout kit via CRISPR

ADORA2B - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

ADORA2B overexpression lysate

ADORA2B overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, ADORA2B (mGFP-tagged) - Human adenosine A2b receptor (ADORA2B), 200 uL, >10^7 TU/mL

Lenti ORF particles, ADORA2B (mGFP-tagged) - Human adenosine A2b receptor (ADORA2B), 200 uL, >10^7 TU/mL  
200 µl / €960.00
  OriGene Technologies, Inc.

Lenti ORF particles, ADORA2B (Myc-DDK tagged) - Human adenosine A2b receptor (ADORA2B) , 200 uL, >10^7 TU/mL

Lenti ORF particles, ADORA2B (Myc-DDK tagged) - Human adenosine A2b receptor (ADORA2B) , 200 uL, >10^7 TU/mL  
200 µl / €860.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Adora2b (GFP-tagged ORF) - Rat adenosine A2B receptor (Adora2b), 200 uL, >10^7 TU/mL

Lenti ORF particles, Adora2b (GFP-tagged ORF) - Rat adenosine A2B receptor (Adora2b), 200 uL, >10^7 TU/mL  
200 µl / €880.00
  OriGene Technologies, Inc.

Lenti ORF particles, Adora2b (Myc-DDK-tagged ORF) - Rat adenosine A2B receptor (Adora2b), 200 uL, >10^7 TU/mL

Lenti ORF particles, Adora2b (Myc-DDK-tagged ORF) - Rat adenosine A2B receptor (Adora2b), 200 uL, >10^7 TU/mL  
200 µl / €780.00
  OriGene Technologies, Inc.

17 Item(s)

per page
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