Adenosine receptor A2b antibody

Principal name

Adenosine receptor A2b antibody

Alternative names for Adenosine receptor A2b antibody

ADORA2B

SwissProt ID

P29275 (Human), P29276 (Rat), Q1LZD0 (Bovin), Q60614 (Mouse), Q6W3F4 (Canfa)

Gene ID

136 (ADORA2B)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Eq (Equine), Mky (Monkey), Can (Canine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit, Goat, Mouse

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Flow Cytometry (F)

Background of Adenosine receptor A2b antibody

Adenosine is an endogenous nucleoside generated locally in tissues under conditions of hypoxia, ischemia, or inflammation. It modulates a variety of physiological functions in many tissues including brain and heart. Adenosine exerts its action via four specific adenosine receptors (also med P1 purinergic receptors): A1-Adenosine Receptor (A1AR), A2A-Adenosine Receptor (A2AAR), A2B-Adenosine Receptor (A2BAR), and A3-Adenosine Receptor (A3AR). All are integral membrane proteins and members of the G Protein-Coupled Receptor superfamily. They share a common structure of seven putative transmembrane domains, an extracellular amino terminus, a cytoplasmic carboxyl terminus, and a third intracellular loop that is important in binding G proteins. The various adenosine receptors can be distinguished on the basis of their distinct molecular structures, distinct tissue distributions, and differential selectivity for adenosine alogs. The A2 Adenosine receptor subtype was subdivided according to affinity for adenosine; A2AAR has high affinity and A2BAR has low affinity. A2BAR is expressed in mast cells, neutrophils, monocytes, macrophages, dendritic cells, T cells, bronchial epithelium, intestil epithelium, smooth muscle, brain, and other cells. In intestil epithelia, A2BAR was found to be the major adenosine receptor subtype expressed and is thought to be involved in diarrheal diseases. It is also believed to be involved in the pathogenesis of chronic airway inflammatory diseases. Thus, antagonists of A2BAR might be effective for the treatment of inflammatory gastrointestil tract disorders as well as asthma and chronic obstructive pulmory disease.

General readings

Bazzichi L, Trincavelli L, Rossi A, De Feo F, Lucacchini A, Bombardieri S, Martini C. A2B adenosine receptor activity is reduced in neutrophils from patients with systemic sclerosis.Arthritis Res Ther. 2005;7(2):R189-95. Epub 2004 Dec 10. PMID: 15743465 [PubMed - in process

14 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Adenosine receptor A2b (C-term) antibody

TA305620 (2µg/ml) staining of paraffin embedded Human Kidney. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining. Goat Aff - Purified Hu E, P
0.1 mg / €325.00
  OriGene Technologies, Inc.

Adenosine receptor A2b antibody

Western blot analysis of HL-60 (lanes 1 and 2) cell line, rat brain (lanes 3 and 4) and mouse brain (lanes 5 and 6) lysates: 1,3,5. Anti-A2B Adenosine Receptor (extracellular) antibody, (1:200). 2,4,6. Anti-A2B Adenosine Receptor (extracellular) antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt P, WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

Adenosine receptor A2b antibody

Anti-Adenosine A2b Receptor antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Purified Eq, Hu, Mky P
50 µg / €379.00
  OriGene Technologies, Inc.

Adenosine receptor A2b antibody

WB Suggested Anti-ADORA2B Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: 293T cell lysate Rabbit IgG Purified Can, Eq, GP, Hu, Por, Rb WB
50 µg / €325.00
  OriGene Technologies, Inc.

Adenosine receptor A2b antibody

Western blot analysis of ADORA2B in mouse colon tissue lysate with ADORA2B antibody at (A) 0.5 and (B) 1 ug/mL. Rabbit IgG Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Adenosine receptor A2b antibody

Western blot analysis of Adenosine A2B-R Antibody (Cat.-No AP01260PU-N) in extracts from J Jurkat cells. Rabbit Aff - Purified Hu E, ICC/IF, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Adenosine receptor A2b antibody

Adenosine receptor A2b Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

Adenosine receptor A2b antibody

Adenosine receptor A2b Goat Hu E
0.1 mg / €400.00
  Abnova Taiwan Corp.

Adenosine receptor A2b antibody

Immunofluorescence analysis of LOVO cells, using ADORA2B Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF, WB
50 µg / €205.00
  Assay Biotech

Adenosine receptor A2b antibody

Immunofluorescence analysis of LOVO cells, using ADORA2B Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF, WB
0.1 mg / €310.00
  Assay Biotech

Adenosine receptor A2b (C-term) antibody

Adenosine receptor A2b Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

Adenosine receptor A2b antibody

Immunohistochemistry: Adenosine A2b Receptor Antibody [NB600-797] -  Adenosine A2b Receptor Antibody [NB600-797]- 3ug/ml staining of paraffin embedded Human Kidney. Microwaved antigen retrieval with Tris/EDTA buffer pH9, HRP-staining. Goat IgG Aff - Purified Hu E, P
0.1 mg / €400.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Adenosine receptor A2b

Adenosine receptor A2b Human
2 µg / €450.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

ADORA2B overexpression lysate

ADORA2B overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

14 Item(s)

per page
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