AE2 / SLC4A2 antibody

Principal name

AE2 / SLC4A2 antibody

Alternative names for AE2 / SLC4A2 antibody

Anion exchanger 2, AE-2, EPB3L1, HKB3, MPB3L, BND3L, Anion exchange protein 2, Non-erythroid band 3-like protein, Solute carrier family 4 member 2

SwissProt ID

P04920 (Human), P13808 (Mouse), P23347 (Rat)

Gene ID

6522 (SLC4A2), 886522 (aspC)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chimp (Chimpanzee), Eq (Equine), GP (Guinea Pig), Hst (Hamster), Mky (Monkey), Ms (Mouse), Por (Porcine), Rb (Rabbit), Rt (Rat), Gorilla, Ye (Yeast)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of AE2 / SLC4A2 antibody

Primary canalicular bile undergoes a process of fluidization and alkalinization along the biliary tract that is influenced by several factors, including hormones, innervation/neuropeptides and biliary constituents. The excretion of bicarbonate at both the canaliculi and the bile ducts is an important contributor to the generation of bile-salt independent flow. Bicarbonate is secreted from hepatocytes and cholangiocytes through parallel mechanisms, which involve chloride efflux through activation of chloride channels and further bicarbonate secretion via AE2 (also designated SLC4A2)-mediated chloride/bicarbonate exchange. The AE2 protein regulates pH, chloride concentration, cell volume and transepithelial ion transport in many tissues. Gene silencing of AE2 causes a marked inhibition of unstimulated and secretin-stimulated chloride/bicarbonate exchange, which maintains the bile acid pool that is crucial for secretin to induce bicarbonate-rich choleresis.

General readings

"Complete nucleotide sequence of band 3 related anion transport protein AE2 from human kidney." Gehrig H., Mueller W., Appelhans H. Biochim. Biophys. Acta 1130:326-328(1992)

8 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

AE2 / SLC4A2 antibody

Anti-SLC4A2 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit IgG Purified Bov, Can, Chimp, Eq, GP, Hst, Hu, Mky, Ms, Por, Rb, Rt
50 µg / €345.00
  OriGene Technologies, Inc.

AE2 / SLC4A2 antibody

Anti-SLC4A2 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit IgG Purified Chimp, Gorilla, Hu, Mky
50 µg / €345.00
  OriGene Technologies, Inc.

AE2 / SLC4A2 antibody

WB Suggested Anti-SLC4A2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: ACHN cell lysate;SLC4A2 is supported by BioGPS gene expression data to be expressed in ACHN Rabbit Aff - Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

AE2 / SLC4A2 antibody

Human ACHN; WB Suggested Anti-SLC4A2 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: ACHN cell lysate. SLC4A2 is supported by BioGPS gene expression data to be expressed in ACHN.; SLC4A2 antibody - N-terminal region (ARP43829_P050) in Human ACHN cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

AE2 / SLC4A2 antibody

Western Blot: AE2 Antibody [NBP1-59858] - This Anti-SLC4A2 antibody was used in Western Blot of ACHN       tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

AE2 / SLC4A2 antibody

Immunohistochemistry-Paraffin: AE2 Antibody [NBP1-90225] Immunohistochemical staining of human stomach shows strong cytoplasmic and membranous positivity in glandular cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

AE2 / SLC4A2

AE2 / SLC4A2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

AE2 / SLC4A2

AE2 / SLC4A2 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

8 Item(s)

per page
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