AF1P / EPS15 antibody

Principal name

AF1P / EPS15 antibody

Alternative names for AF1P / EPS15 antibody

Protein AF-1p, Epidermal growth factor receptor substrate 15

SwissProt ID

P42566 (Human), P42567 (Mouse)

Gene ID

2060 (EPS15)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), Por (Porcine), Rb (Rabbit)

Available hosts

Rabbit

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Enzyme Immunoassay (E)

Background of AF1P / EPS15 antibody

EPS15 is involved in cell growth regulation, possibly via the regulation of mitogenic signals and control of cell proliferation. EPS15 also participates in the internalization of ligand-inducible receptors of the receptor tyrosine kinase (RTK) type, in particular EGFR. Potential interaction partners include AP2A2, STN2, EPN1, and CRK via its SH3-binding sites. EPS15 is ubiquitously expressed. Phosphorylation on Tyr-849 is involved in the internalization of EGFR. EPS15 is not required for membrane translocation after EGF treatment or for targeting to coated pits, but essential for a subsequent step in EGFR endocytosis. This protein is involved in a t(1;11)(p32;q23) chromosomal translocation in acute leukemias causing fusion to the trithorax (MLL or HRX) gene product which contains DNA-binding motifs resulting in a rogue activator protein. Structurally, EPS15 contains 2 EF-hand calcium-binding domains, 3 EH domains, and 2 ubiquitin-interacting motif (UIM) repeats.

General readings

Niehof,M. (2008) Gastroenterology 134 (4), 1191-1202

18 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

AF1P / EPS15 antibody

Western Blot: EPS15 Antibody - Western blot analysis of EPS15 on Mouse brain lysate using anti-EPS15. Rabbit Purified Hu, Ms, Rt C, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

AF1P / EPS15 antibody

WB Suggested Anti-EPS15 Antibody Titration: 0.2-1 ug/ml; Positive Control: 721_B cell lysateEPS15 is supported by BioGPS gene expression data to be expressed in 721_B Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

AF1P / EPS15 (C-term) antibody

Western blot analysis of anti-EPS15 (C-term) Pab (Cat.#AP12062PU-N) in HL60 cell line lysate (35ug/lane). EPS15 (arrow) was detected using the purified Pab. Rabbit Ig Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

AF1P / EPS15 pTyr849 antibody

Western blot analysis of extracts from JK cells (Lane 2), using EPS15 (Phospho-Tyr849) Antibody AP55818PU-N. The lane on the left is treated with antigen-specific peptide. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 ml / €340.00
  Acris Antibodies GmbH

AF1P / EPS15 pTyr849 antibody

Western blot analysis of extracts from JK cells (Lane 2), using EPS15 (Phospho-Tyr849) Antibody AP55818PU-N. The lane on the left is treated with antigen-specific peptide. Rabbit Aff - Purified Hu, Ms, Rt WB
50 µl / €270.00
  Acris Antibodies GmbH

AF1P / EPS15 antibody

Western blot analysis of EPS15 polyclonal antibody ( Cat # PAB1705 ) in HL-60 cell line lysate ( 35 µg/lane ) . EPS15 ( arrow ) was detected using the purified polyclonal antibody. Rabbit Hu E, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

AF1P / EPS15 antibody

Immunofluorescent staining of EPS15 on rat fibroblasts using EPS15 polyclonal antibody ( Cat # PAB12437 ). Rabbit Hu, Ms, Rt ICC/IF, IP, WB
0.1 ml / €470.00
  Abnova Taiwan Corp.

AF1P / EPS15 antibody

Human 721_B; WB Suggested Anti-EPS15 Antibody Titration: 0.2-1 ug/ml. Positive Control: 721_B cell lysate. EPS15 is supported by BioGPS gene expression data to be expressed in 721_B.; EPS15 antibody - C-terminal region (ARP54601_P050) in Human 721_B cells using Western Blot Rabbit Aff - Purified Bov, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

AF1P / EPS15 antibody

Immunofluorescence: EPS15 Antibody [NB110-74688] - Immunofluorescent staining of rat fibroblasts using NB110-74688. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, IP, WB
0.2 ml / €360.00
  Novus Biologicals Inc.

AF1P / EPS15 antibody

AF1P / EPS15 Rabbit Biotin Hu, Ms, Rt ICC/IF, IP, WB
0.2 ml / €550.00
  Novus Biologicals Inc.

AF1P / EPS15 antibody

AF1P / EPS15 Rabbit DyLight488 Hu, Ms, Rt ICC/IF, IP, WB
0.2 ml / €570.00
  Novus Biologicals Inc.

AF1P / EPS15 antibody

AF1P / EPS15 Rabbit HRP Hu, Ms, Rt ICC/IF, IP, WB
0.2 ml / €570.00
  Novus Biologicals Inc.

AF1P / EPS15 antibody

AF1P / EPS15 Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, IP, WB
50 µl / €160.00
  Novus Biologicals Inc.

AF1P / EPS15 antibody

AF1P / EPS15 Rabbit Biotin Ms, Rt ICC/IF, IP, WB
0.1 ml / €380.00
  Novus Biologicals Inc.

AF1P / EPS15 antibody

AF1P / EPS15 Rabbit DyLight488 Ms, Rt ICC/IF, IP, WB
0.1 ml / €390.00
  Novus Biologicals Inc.

AF1P / EPS15 antibody

AF1P / EPS15 Rabbit HRP Ms, Rt ICC/IF, IP, WB
0.1 ml / €390.00
  Novus Biologicals Inc.

AF1P / EPS15 antibody

AF1P / EPS15 Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, IP, WB
25 µl / €160.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

AF1P / EPS15

AF1P / EPS15 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

18 Item(s)

per page
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