AGAP2 / CENTG1 antibody

Principal name

AGAP2 / CENTG1 antibody

Alternative names for AGAP2 / CENTG1 antibody

Centaurin-gamma-1, KIAA0167, GGAP2, PIKE, Arf-GAP GTPase ANK repeat and PH domain-containing protein 2, Phosphatidylinositol-3-kinase enhancer, GTP-binding and GTPase-activating protein 2

SwissProt ID

Q3UHD9 (Mouse), Q8CGU4 (Rat), Q99490 (Human)

Gene ID

116986 (AGAP2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Rabbit, Goat

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of AGAP2 / CENTG1 antibody

Phosphoinositide 3 kinase enhancer (PIKE) is a recently identified nuclear GTPase that interacts with nuclear phosphoinositide 3-kinase (PI3 kinase) to stimulate its lipid kinase activity (1). PIKE exists in multiple isoforms; a shorter C-terminal isoform (PIKE-A) has also been identified as centaurin gamma 1 (reviewed in 2). The longest isoform (PIKE-L) has been shown to bind to the adaptor protein Homer and thereby link to metabotropic glutamate receptors, leading to activation of PI3 kinase activity and prevention of neuronal apoptosis (3). Overexpression of PIKE-A enhances Akt activity and promotes cancer cell invasion, whereas decreased expression of PIKE-A via dominant negative expression of PIKE-A or PIKE-A knockdown inhibits these processes (4). In many human cancers, expression of PIKE-A is enhanced, leading to increased Akt activity and preventing apoptosis.

19 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

AGAP2 / CENTG1 antibody

TA305917 (0.3ug/ml) staining of Human Amygdala lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

AGAP2 / CENTG1 (C-term) antibody

Western blot analysis of PIKE in mouse brain cell lysates with PIKE antibody at (A) 0.5, (B) 1, and (C) 2 ug/ml. Rabbit IgG Purified Hu, Ms E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

AGAP2 / CENTG1 (1-836) antibody

Western blot using Protein A purified anti-AGAP2 antibody shows detection of AGAP2 recombinant protein in transfected HEK293 cell lysates. No specific band staining is noted in mock transfected cell lysates (empty vector). The membrane was probed with the primary antibody diluted to 1:10,000. Personal Communication, Paul Randazzo, CCR-NCI, Bethesda, MD. Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

AGAP2 / CENTG1 antibody

WB Suggested Anti-CENTG1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: THP-1 cell lysate Rabbit IgG Purified Bov, Eq, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

AGAP2 / CENTG1 (C-term) antibody

Heart: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit Purified Hu, Ms P, WB
50 µg / €470.00
  Acris Antibodies GmbH

AGAP2 / CENTG1 (1-836) antibody

Brain, cortex: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit Purified Hu, Ms, Rt E, ICC/IF, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

AGAP2 / CENTG1 Control Peptide

AGAP2 / CENTG1
50 µg / €160.00
  Acris Antibodies GmbH

AGAP2 / CENTG1 (C-term) antibody

CENTG1 Antibody (C-term) (Cat. #AP50861PU-N) western blot analysis in mouse brain tissue lysates (35µg/lane).This demonstrates the CENTG1 antibody detected the CENTG1 protein (arrow). Rabbit Ig Aff - Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

AGAP2 / CENTG1 (Isoform 2) antibody

AGAP2 / CENTG1 Rabbit Serum Hu E, ICC/IF, WB
0.2 ml / €400.00
  Acris Antibodies GmbH

AGAP2 / CENTG1 antibody

Western blot using AGAP2 polyclonal antibody ( Cat # PAB9929 ) shows detection of AGAP2 recombinant protein in transfected HEK293 cell lysates.
No specific band staining is noted in mocktransfected cell lysates ( empty vector ).
The membrane was probed with the primary antibody diluted to 1 : 10,000.
Personal Communication, Paul Randazzo, CCR-NCI, Bethesda, MD. Hu, Ms, Rt
0.1 mg / €560.00
  Abnova Taiwan Corp.

AGAP2 / CENTG1 antibody

Immunohistochemistry of AGAP2 in mouse brain tissue with AGAP2 polyclonal antibody ( Cat # PAB12921 ) at 10 µg/ml. Rabbit Hu, Ms P, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

AGAP2 / CENTG1 antibody

AGAP2 polyclonal antibody ( Cat # PAB14141 ) ( 0.3µg/ml ) staining of human amygdala lysate ( 35µg protein in RIPA buffer ). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

AGAP2 / CENTG1 antibody

AGAP2 / CENTG1 Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

AGAP2 / CENTG1 antibody

AGAP2 / CENTG1 Rabbit Purified Hu, Ms, Rt E, ICC/IF, P, WB
50 µg / €480.00
  Novus Biologicals Inc.

AGAP2 / CENTG1 antibody

AGAP2 / CENTG1 Goat Aff - Purified Hu E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

AGAP2 / CENTG1 antibody

Immunohistochemistry-Paraffin: AGAP2 Antibody [NBP1-77194] - PIKE in mouse brain tissue with PIKE antibody at 10 ug/mL._x000d_ Rabbit Purified Hu, Ms E, P, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

AGAP2 / CENTG1 antibody

Immunohistochemistry-Paraffin: AGAP2 Antibody [NBP1-85686] - Immunohistochemical staining of human cerebellum shows distinct cytoplasmic positivity in Purkinje cells. Rabbit IgG Aff - Purified Hu ICC/IF, P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

AGAP2 / CENTG1

AGAP2 / CENTG1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue
10 µg / €380.00
  Abnova Taiwan Corp.

AGAP2 / CENTG1

AGAP2 / CENTG1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue
25 µg / €510.00
  Abnova Taiwan Corp.

19 Item(s)

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