Aggrecan antibody

Principal name

Aggrecan antibody

Alternative names for Aggrecan antibody

ACAN, AGC1, CSPG1, MSK16, Cartilage-specific proteoglycan core protein, Chondroitin sulfate proteoglycan core protein 1

SwissProt ID

P07897 (Rat), P13608 (Bovin), P16112 (Human), Q61282 (Mouse)

Gene ID

176, 58968 (Acan)

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Ms (Mouse), Rt (Rat), Eq (Equine), Fe (Feline), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Sh (Sheep), Bt (Bat), Hst (Hamster), Mky (Monkey), Bear

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Frozen Sections (C), Enzyme Immunoassay (E), Paraffin Sections (P), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF), ELISA (detection) (E(detection))

Background of Aggrecan antibody

Aggrecan Neoepitope (ACAN) is a proteoglycan belonging to aggrecan/versican proteoglycan family and is a major component of extracellular matrix of cartilagenous tissues. ACAN proteoglycan is mainly consists of chondroitin sulfate, however, it also contains keratan sulfate chains, N/O-linked oligosaccharides. Aggrecase mediated cleavage results in ACAN fragments release from articular cartilage into synovial fluid during different stages of human osteoarthritis. ACAN is a secreted protein found in extracellular space/extracellular matrix and is more or less restricted to cartilages where it interact with FBLN1 as well as COM for serving the role of resisting compression in cartilage. ACAN binds to hyaluronic acid via an N-termil globular region with high avidity and its expression occurs in chondrocytes throughout the developing skeleton. ACAN defects have been linked to spondyloepiphyseal dysplasia type Kimberley (SEDK), spondyloepimetaphyseal dysplasia aggrecan type (SEMD-ACAN), osteochondritis dissecans short stature and early-onset osteoarthritis (OD).

General readings

This product has been used in:Little CB et al. Matrix metalloproteinases are involved in C-terminal and interglobular domain processing of cartilage aggrecan in late stage cartilage degradation. Matrix Biol 21:271-88 (2002). PubMed PMID: 12009333
Caterson B et al. Mechanisms involved in cartilage proteoglycan catabolism. Matrix Biol 19:333-44 (2000). PubMed PMID: 10963994

  1. Quick-Filters:
  2. Cited (1)
  3. Highly Validated (1)

Items 1 to 20 of 29 total

per page
Page:
  1. 1
  2. 2

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Aggrecan antibody

Recombinant Human Aggrecan detected with Aggrecan Antibody Cat.-No SM1353P followed by Goat anti Mouse IgG -Dylight®800. Visualised using a LI-COR Odyssey® infrared imaging system. Mouse IgG1 HAG7D4 (7D4) Purified Bov, Hu C, E, IP, P, WB
0.2 mg / €570.00
  Acris Antibodies GmbH

Aggrecan antibody

Western Blot: Aggrecan Neoepitope Antibody [TA336492] - Analysis of ACAN in L929 whole cell extract using TA336492. Rabbit Purified Bov, Can, Hu, Ms, Por, Rt C, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Aggrecan antibody

Anti-ACAN / Aggrecan antibody IHC of human cartilage. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit IgG Purified Bov, Bt, Can, Eq, Hst, Hu, Mky, Ms, Rt P
50 µg / €345.00
  OriGene Technologies, Inc.

Aggrecan antibody

Immunohistochemistry-Paraffin: Aggrecan Antibody (6-B-4) [TA336544] - Aggrecan on sheep intervertebral disc. Image from verified customer review. Mouse IgG1 6-B-4 Purified Bov, Hu C, E, P, WB
1 ml / €379.00
  OriGene Technologies, Inc.

Aggrecan (N-term) antibody

Anti-ACAN / Aggrecan antibody IHC of human bone, cartilage. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit IgG Aff - Purified Bear, Bov, Bt, Can, Elephant, Eq, Hst, Hu, Mky, Ms, Por, Rt P
50 µg / €379.00
  OriGene Technologies, Inc.

Aggrecan (C-term) antibody

Anti-ACAN / Aggrecan antibody IHC of human cartilage. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu, Mky P
50 µg / €379.00
  OriGene Technologies, Inc.

Aggrecan antibody

Anti-ACAN / Aggrecan antibody IHC of human cartilage. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Purified Hu, Ms P
50 µg / €379.00
  OriGene Technologies, Inc.

Aggrecan antibody

Aggrecan Mouse IgG1 4G4/A10 Purified Hu E, P, WB
0.1 mg / €510.00
  Acris Antibodies GmbH

Aggrecan antibody

Aggrecan Mouse IgG1 4G4/A10 Purified Hu E, P, WB
10 µg / €150.00
  Acris Antibodies GmbH

Aggrecan antibody

Aggrecan Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

Aggrecan antibody

Detection limit for recombinant GST tagged AGC1 is approximately 0.1ng/ml as a capture antibody. Mouse IgG1 2A8 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Aggrecan antibody

Aggrecan Mouse IgG1 14A6 3B2 Hu E
1 mg / €990.00
  Abnova Taiwan Corp.

Aggrecan (cleaved) antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using Aggrecan (Cleaved-Asp369) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Rt E, P, WB
50 µg / €205.00
  Assay Biotech

Aggrecan (cleaved) antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using Aggrecan (Cleaved-Asp369) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Rt E, P, WB
0.1 mg / €310.00
  Assay Biotech

Aggrecan antibody

Immunohistochemical analysis of Aggrecan staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Bov, Can, Hu, Ms, Por, Rb, Rt, Sh P, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

Aggrecan antibody

Immunohistochemical analysis of Aggrecan staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Bov, Can, Hu, Ms, Por, Rb, Rt, Sh P, WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

Aggrecan antibody

Immunohistochemical analysis of Aggrecan staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Bov, Can, Hu, Ms, Por, Rb, Rt, Sh P, WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

Aggrecan (Neoepitope) antibody

ACAN staining of OA cartilage. Rabbit IgG Aff - Purified Bov, Fe, Hu, Ms, Por, Rt ICC/IF, WB
0.1 ml / €490.00
  Neuromics Antibodies

Aggrecan antibody

Aggrecan Rabbit Hu E, WB
50 µg / €400.00
  Novus Biologicals Inc.

Aggrecan control peptide

Aggrecan JSCNIT Bov, Can, Hu, Ms, Por, Rt
0.1 mg / €420.00
  Novus Biologicals Inc.

Items 1 to 20 of 29 total

per page
Page:
  1. 1
  2. 2
  • LinkedIn