AGR2 antibody

Principal name

AGR2 antibody

Alternative names for AGR2 antibody

Anterior gradient protein 2 homolog, AG2, AG-2, HPC8, Secreted cement gland protein XAG-2 homolog

SwissProt ID

O88312 (Mouse), O95994 (Human)

Gene ID

10551 (AGR2), 23795 (Agr2)

Available reactivities

Hu (Human), Bov (Bovine), Chk (Chicken), Ms (Mouse), Rt (Rat), Ze (Zebrafish), Can (Canine), Fe (Feline), Hst (Hamster), Eq (Equine)

Available hosts

Mouse, Goat, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Frozen Sections (C)

Background of AGR2 antibody

Origilly discovered in Xenopus laevis wherein it plays a role during early neural development, AGR2 (anterior gradient protein 2 homolog) is now known as a member of protein disulfide isomerase (PDI) family of ER-resident proteins which is expressed in a variety of normal as well as transformed epithelial tissues. AGR2 has been implicated in the folding of proteins as a chaperone protein. It interacts with LYPD3, DAG1 (alphaDAG1) and MUC2 (disulfide-linked), and is essential for MUC2 translation as well as secretion. AGR2 plays a key role in the production of mucus by intestil cells and has also been suggested to be a proto-oncogene that may involve in cellular migration, differentiation and growth. Differential expression of AGR2 was first found in estrogen receptor (ER)-positive breast cancer cell lines and subsequently, elevated AGR2 levels have been seen in subsets of other cancers also wherein its upregulation enhances classical hallmarks of cancer such as metastasis, invasion, colony formation, and proliferation.

General readings

General / background references:Fletcher GC et al. hAG-2 and hAG-3, human homologues of genes involved in differentiation, are associated with oestrogen receptor-positive breast tumours and interact with metastasis gene C4.4a and dystroglycan. Br J Cancer 88:579-85 (2003). PubMed PMID: 12592373
Petek E et al. Localization of the human anterior gradient-2 gene (AGR2) to chromosome band 7p21.3 by radiation hybrid mapping and fluorescencein situ hybridisation. Cytogenet Cell Genet 89:141-2 (2000). PubMed PMID: 10965104

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

AGR2 antibody

AGR2 Antibody (Center) (Cat. #TA324828) western blot analysis in HT29,MCF-7,ZR-75-1 cell line lysates (35ug/lane).This demonstrates the AGR2 antibody detected the AGR2 protein (arrow). Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

AGR2 antibody

Western Blot: AGR2 Antibody [TA336716] - Human stomach lysate. Rabbit Purified Bov, Hu, Ms C, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

AGR2 antibody

Western Blot: AGR2 Antibody (10E2) [TA337147] - analysis of human stomach in the A) absense and B) presence of immunizing peptide, C) mouse stomach, D) rat stomach tissue lysate, and E) HCT-116 cell lysate using AGR2 antibody at 5 ug/ml. Goat anti-mouse I Mouse 1E3 Purified Bov, Can, Eq, Hu, Ms C, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

AGR2 antibody

Western Blot: AGR2 Antibody [TA337169] - analysis of AGR2 using AGR2 antibody. MCF7 (A), Caco-2 (B) and human stomach lysate © probed with AGR2 antibody at 1:100. were used for this test. The higher molecular weight band of variable intensity at Rabbit Purified Hu, Ms C, IP, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

AGR2 antibody

AGR2 monoclonal antibody (M01), clone 1E5. Western Blot analysis of AGR2 expression in human colon. Mouse IgG2b 1E5 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

AGR2 antibody

TA303161 (0.01µg/ml) staining of Human Duodenum lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

AGR2 antibody

Western blot analysis of AGR2 in Hela cell lysate with AGR2 antibody at (A) 1 and (B) 2 ug/mL Rabbit IgG Purified Hst, Hu ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

AGR2 antibody

Predicted band size: 20kDa. Positive control: Mouse large intestine tissue lysate. Recommended dilution: 1/1000-5000. (Gel: 10%SDS-PAGE Lysate: 40 ug Primary antibody: 1/1000 dilution Secondary antibody: Donkey anti Rabbit IgG - H&L (HRP) at 1/3000 dilution Exposure time: 20 seconds) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

AGR2 antibody

Predicted band size: 20kDa. Positive control: Mouse large intestine tissue lysate. Recommended dilution: 1/1000-5000 Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

AGR2 (N-term) antibody

AGR2 Antibody (N-term) (Cat. #TA324827) western blot analysis in HT29,MCF-7,ZR-75-1 cell line lysates (35ug/lane).This demonstrates the AGR2 antibody detected the AGR2 protein (arrow). Rabbit Ig Purified Hu P, WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

AGR2 antibody

Immunohistochemistry-Paraffin: AGR2 Antibody [TA336509] - Immunohistochemical staining with TA336509, anti-AGR2 antibody, in formalin-fixed, paraffin-embedded normal colon tissue at 1:100 dilution. Rabbit Purified Hu C, P
50 µl / €325.00
  OriGene Technologies, Inc.

AGR2 antibody

Immunohistochemistry: AGR2 Antibody [TA336715] - Detection of AGR2 in mouse kidney. Rabbit Purified Hu, Ms C, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

AGR2 (55-72) antibody

Colon: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit IgG Purified Bov, Can, Eq, Hu, Mky, Por, Rb E, P
50 µg / €470.00
  Acris Antibodies GmbH

AGR2 (48-59) antibody

Human Colon (formalin-fixed, paraffin-embedded) stained with AGR2 antibody AP22561PU-N followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Goat Aff - Purified Bear, Can, Eq, Hst, Hu, Mky, Ms, Por, Prim, Rb, Rt E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

AGR2 antibody

AGR2 Rabbit Serum Hu C, E, WB
0.2 ml / €400.00
  Acris Antibodies GmbH

AGR2 antibody

AGR2 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

AGR2 antibody

AGR2 monoclonal antibody (M01), clone 1E5. Western Blot analysis of AGR2 expression in human colon. Mouse IgG2b 1E5 Ascites Hu E, WB
0.2 ml / €370.00
  Abnova Taiwan Corp.

AGR2 antibody

AGR2 monoclonal antibody (M02), clone 3G1. Western Blot analysis of AGR2 expression in MCF-7 ( Cat # L046V1 ). Mouse IgG2b 3G1 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

AGR2 antibody

AGR2 monoclonal antibody (M03), clone 1C3 Western Blot analysis of AGR2 expression in MCF-7 ( Cat # L046V1 ). Mouse IgG2b 1C3 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

AGR2 antibody

AGR2 Mouse IgG2b 7E9 Ascites Hu E, WB
0.2 ml / €370.00
  Abnova Taiwan Corp.

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