AGTPBP1 / CCP1 antibody

Principal name

AGTPBP1 / CCP1 antibody

Alternative names for AGTPBP1 / CCP1 antibody

ATP/GTP-binding protein 1, Cytosolic carboxypeptidase 1, KIAA1035, NNA1, Nervous system nuclear protein induced by axotomy

SwissProt ID

Q641K1 (Mouse), Q9UPW5 (Human)

Gene ID

23287 (AGTPBP1), 67269 (Agtpbp1)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Ms (Mouse), Rt (Rat), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Eq (Equine), Ze (Zebrafish)

Available hosts

Mouse, Goat, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F), Paraffin Sections (P)

Background of AGTPBP1 / CCP1 antibody

Agtpbp1 is a metallocarboxypeptidase that mediates deglutamylation of target proteins. It catalyzes the deglutamylation of polyglutamate side chains generated by post-translatiol polyglutamylation in proteins such as tubulins. It also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Agtpbp1 acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5. Deglutamylation plays a key role in cerebellar Purkinje cell differentiation, accumulation of tubulin polyglutamylation causing neurodegeneration.

General readings

1. Escalier D. Knockout mouse models of sperm flagellum anomalies. A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. Hum Reprod Update. 2006 Jul-Aug;12(4):449-61.
PMID: 16565154

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

AGTPBP1 / CCP1 antibody

Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-AGTPBP1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA800234) Mouse IgG1 OTI9A3 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

AGTPBP1 / CCP1 antibody

(1ug/ml) staining of HeLa lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

AGTPBP1 / CCP1 antibody

Host: Rabbit; Target Name: Agtpbp1; Sample Tissue: Mouse Testis lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

AGTPBP1 / CCP1 antibody

WB Suggested Anti-AGTPBP1 Antibody Titration: 0.2-1 ug/ml; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

AGTPBP1 / CCP1 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY AGTPBP1 (RC209238, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-AGTPBP1. Mouse IgG1 OTI1C8 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

AGTPBP1 / CCP1 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY AGTPBP1 (RC209238, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-AGTPBP1. Mouse IgG1 OTI9B8 Purified Hu F, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

AGTPBP1 / CCP1 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY AGTPBP1 (RC209238, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-AGTPBP1. Mouse IgG1 OTI9D11 Purified Hu WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

AGTPBP1 / CCP1 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY AGTPBP1 (RC209238, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-AGTPBP1. Mouse IgG1 OTI9C8 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

AGTPBP1 / CCP1 antibody

Western Blot analysis of AGTPBP1 expression in transfected 293T cell line by AGTPBP1 polyclonal antibody (A01).

Lane1:AGTPBP1 transfected lysate(138.448 KDa).
Lane2:Non-transfected lysate. Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

AGTPBP1 / CCP1 antibody

Immunofluorescence of purified MaxPab antibody to AGTPBP1 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Serum Hu E(detection), ICC/IF, WB
50 µl / €370.00
  Abnova Taiwan Corp.

AGTPBP1 / CCP1 antibody

AGTPBP1 monoclonal antibody (M03), clone 2B9. Western Blot analysis of AGTPBP1 expression in HepG2 ( Cat # L019V1 ). Mouse IgG1 2B9 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

AGTPBP1 / CCP1 (N-term) antibody

Human HepG2; WB Suggested Anti-AGTPBP1 Antibody Titration: 0.2-1 ug/ml. Positive Control: HepG2 cell lysate; AGTPBP1 antibody - N-terminal region (ARP55205_P050) in Human HepG2 cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

AGTPBP1 / CCP1 antibody

AGTPBP1 / CCP1 Goat Aff - Purified Bov, Can, Hu, Ms, Rt E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

AGTPBP1 / CCP1 antibody

AGTPBP1 / CCP1 Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

AGTPBP1 / CCP1

AGTPBP1 / CCP1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

AGTPBP1 / CCP1

AGTPBP1 / CCP1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

AGTPBP1 / CCP1

AGTPBP1 / CCP1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

AGTPBP1 293T Cell Transient Overexpression Lysate(Denatured)

AGTPBP1 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

18 Item(s)

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