Ah receptor / AhR antibody

Principal name

Ah receptor / AhR antibody

Alternative names for Ah receptor / AhR antibody

AHR, BHLHE76, Aryl hydrocarbon receptor

SwissProt ID

O02747 (Rabit), P30561 (Mouse), P35869 (Human), P41738 (Rat)

Gene ID

196 (AHR), 11622 (Ahr)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Por (Porcine), Rb (Rabbit), GP (Guinea Pig), Chk (Chicken), Ze (Zebrafish), Bt (Bat), Eq (Equine), Hst (Hamster), Mky (Monkey), Prim (Primate), Bear

Available hosts

Mouse, Rabbit, Goat

Available applications

Frozen Sections (C), ChIP assay (ChIP), Enzyme Immunoassay (E), Electrophoretic Mobility Shift Assay (EMSA), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Paraffin Sections (P), Western blot / Immunoblot (WB), ELISA (detection) (E(detection))

Background of Ah receptor / AhR antibody

Aryl hydrocarbon Receptor (AhR) is a ligand-activated transcriptiol activator that binds to XRE promoter region of its target genes and has been established to activate phase I/II xenobiotic biotransformation enzyme genes. AhR binds MYBBP1A and its efficient D binding requires dimerization with another bHLH proteinsuch as ARNT. Besides interacting with NEDD8 and IVNS1ABP, AhR also interacts with coactivators including SRC-1, RIP140 and NOCA7, and with the corepressor SMRT. AhR localize to cytoplasm and upon binding with ligand followed by interaction with a HSP90, it translocates to the nucleus. AhR has been shown to be induced or repressed by TGFB1 as well as dioxin in a cell-type specific fashion, whereas cAMP, retinoic acid, TPA (12-O-tetradecanoyl phorbol-13 acetate) have been shown to exert repressive effects on AhR. As a member of bHLH-PAS (basic helix-loop-helix Per/ARNT/Sim) family, AhR has been implicated in physiological processes such as circadian cycle, neurogenesis, organs development and regulation of cell-cycle as well as the altertive sigling pathways (independently of exposure to xenobiotics). AhR- mice exhibit infertility, liver abnormalities and cardiovascular problems such as a defective closure of the ductus venosus, indicative of the implication of the AhR in various developmental processes.

General readings

This product has been used in:Ray SS & Swanson HI Dioxin-induced immortalization of normal human keratinocytes and silencing of p53 and p16INK4a. J Biol Chem 279:27187-93 (2004). PubMed PMID: 15111621
General / background references:Delescluse C et al. Is CYP1A1 induction always related to AHR signaling pathway? Toxicology 153:73-82 (2000). PubMed PMID: 11090948
Perdew GH et al. Production and characterization of monoclonal antibodies directed against the Ah receptor. Hybridoma 14:279-83 (1995). PubMed PMID: 7590792
Chen HS & Perdew GH Subunit composition of the heteromeric cytosolic aryl hydrocarbon receptor complex. J Biol Chem 269:27554-8 (1994). PubMed PMID: 7961671

  1. Quick-Filters:
  2. Highly Validated (2)

Items 1 to 20 of 49 total

per page
Page:
  1. 1
  2. 2
  3. 3

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Ah Receptor pSer36 antibody

Immunohistochemical analysis of Ah Receptor (pS36) staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Chk, Hu, Ms, Rb, Rt, Ze IP, P, WB
30 µl / €210.00
  Cohesion Biosciences Ltd.

Ah Receptor pSer36 antibody

Immunohistochemical analysis of Ah Receptor (pS36) staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Chk, Hu, Ms, Rb, Rt, Ze IP, P, WB
0.1 ml / €330.00
  Cohesion Biosciences Ltd.

Ah Receptor pSer36 antibody

Immunohistochemical analysis of Ah Receptor (pS36) staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Chk, Hu, Ms, Rb, Rt, Ze IP, P, WB
0.2 ml / €530.00
  Cohesion Biosciences Ltd.

Ah receptor / AhR (N-term) antibody

Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit IgG Hu, Ms, Rt E, ICC/IF, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

Ah receptor / AhR antibody

Immunofluorescence of monoclonal antibody to AHR on HeLa cell. [antibody concentration 10 ug/ml] Mouse IgG1 3B12 Purified Hu E, ICC/IF, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Ah receptor / AhR antibody

Detection of AhR in mouse liver cytosol Rabbit IgG Purified Ms ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Ah receptor / AhR antibody

Western blot analysis of extracts from 293 cells, using Myc (Ab-62) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Ah receptor / AhR antibody

Western blot analysis of AhR expression in 293 whole cell lysates,The lane on the left is treated with the antigen-specific peptide. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Ah receptor / AhR antibody

TA326329 (2µg/ml) staining of paraffin embedded Human Kidney. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining. Goat Aff - Purified Hu P
0.1 mg / €325.00
  OriGene Technologies, Inc.

Ah receptor / AhR (749-763) antibody

TA326720 (0.2µg/ml) staining of HeLa lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Ah receptor / AhR antibody

WB Suggested Anti-AHR Antibody Titration: 2.5 ug/ml; Positive Control: HepG2 cell lysate Rabbit IgG Purified Hu P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Ah receptor / AhR antibody

Western Blot: Aryl hydrocarbon Receptor Antibody [TA336259] - U937 cell nuclear protein. Image from verified customer review. Goat Purified Hu, Ms, Rt EMSA, WB
1 ml / €325.00
  OriGene Technologies, Inc.

Ah receptor / AhR (N-term) antibody

Anti-Aryl Hydrocarbon Receptor antibody IHC of human respiratory epithelium and bronchial smooth muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Bear, Bov, Bt, Can, Eq, GP, Hst, Hu, Mky, Prim P
50 µg / €379.00
  OriGene Technologies, Inc.

Ah receptor / AhR (Internal) antibody

Anti-Aryl Hydrocarbon Receptor antibody IHC of human respiratory epithelium and bronchial smooth muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Can, Hu, Mky, Prim P
50 µg / €379.00
  OriGene Technologies, Inc.

Ah receptor / AhR (Internal) antibody

Anti-Aryl Hydrocarbon Receptor antibody IHC of human respiratory epithelium and bronchial smooth muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu, Mky, Prim P
50 µg / €379.00
  OriGene Technologies, Inc.

Ah receptor / AhR (C-term) antibody

Anti-Aryl Hydrocarbon Receptor antibody IHC of human respiratory epithelium and bronchial smooth muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Bov, Bt, Elephant, GP, Hst, Hu, Mky, Prim P
50 µg / €379.00
  OriGene Technologies, Inc.

Ah receptor / AhR (279-376) antibody

Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG2a 3B9 Purified Hu E, P
50 µg / €530.00
  Acris Antibodies GmbH

Ah receptor / AhR antibody

Immunohistochemistry analysis of AhR antibody (Cat.-No AP20330PU-N) in paraffin-Embedded human breast carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Ah receptor / AhR antibody

Western Blot analysis of AHR expression in transfected 293T cell line (H00000196-T04) by AHR MaxPab polyclonal antibody.

Lane 1: AHR transfected lysate(93.28 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

Ah receptor / AhR antibody

Western Blot analysis of AHR expression in transfected 293T cell line (H00000196-T01) by AHR MaxPab polyclonal antibody.

Lane 1: AHR transfected lysate(96.10 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

Items 1 to 20 of 49 total

per page
Page:
  1. 1
  2. 2
  3. 3
  • LinkedIn