AHNAK / PM227 antibody

Principal name

AHNAK / PM227 antibody

Alternative names for AHNAK / PM227 antibody

Desmoyokin, Neuroblast differentiation-associated protein AHNAK

SwissProt ID

Q09666 (Human)

Gene ID

79026 (AHNAK)

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine)

Available hosts

Mouse, Rabbit, Guinea Pig

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), EPair for Elisa (EPair)

Background of AHNAK / PM227 antibody

AHNAK1 (Desmoyokin) is a large (700 kDa) scaffold protein that translocates to the plasma membrane after an increas of extracellular calcium level or upon proteinkinase C activation and regulates extracellular calcium influx mediated by L-type Ca2+ channels. AHNAK1 has been implicated in diverse signal transduction proceses affecting cell differentiation and proliferation. In response to calcium-dependent intercellular contacts AHNAK1 forms multimeric complexes in the plasma membrane, connected with actin and annexin 2/S100A10 assemblies and is thus involved in organization of the plasma membrane architecture. In epithelial cells, AHNAK1 is localized in cytoplasm or is membrane-associated, but in cells of nonepithelial origin AHNAK1 is predominantly nuclear; it has a weak DNA-binding activity and associates with the DNA-ligase IV-XRCC4 complex.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

AHNAK / PM227 antibody

Immunofluorescence staining of AHNAK1 in human primary fibroblasts using anti-AHNAK1 (green). Actin filaments were decorated by phalloidin (red) and cell nuclei stained with DAPI (blue). Mouse IgG1 EM-09 Purified Hu, Ms C, ICC/IF, IP, WB
0.1 mg / €260.00
  Acris Antibodies GmbH

AHNAK / PM227 antibody

AHNAK / PM227 Guinea Pig Serum Bov, Hu C, ICC/IF, IP, WB
0.1 ml / €380.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

AHNAK - human gene knockout kit via CRISPR

AHNAK - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

AHNAK - human gene knockout kit via CRISPR

AHNAK - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

AHNAK - human gene knockout kit via CRISPR

AHNAK - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

AHNAK - human gene knockout kit via CRISPR

AHNAK - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

AHNAK / PM227 (transcript variant 2)

  Recombinant protein of human AHNAK nucleoprotein (AHNAK), transcript variant 2  
AHNAK / PM227 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

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