AICDA / AID antibody

Principal name

AICDA / AID antibody

Alternative names for AICDA / AID antibody

Cytidine aminohydrolase, Activation-induced cytidine deaminase

SwissProt ID

Q2PT36 (Bovin), Q75W64 (Canfa), Q9GZX7 (Human), Q9WVE0 (Mouse)

Gene ID

57379 (AICDA), 11628 (Aicda)

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Por (Porcine), Rt (Rat)

Available hosts

Rabbit, Goat, Mouse, Rat

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), Dot blot (Dot), Frozen Sections (C)

Background of AICDA / AID antibody

Activation-induced cytidine deaminase (AID) is a 24 kDa, RNA-editing protein that is necessary for the initiation of both somatic hypermutation (SHM) and class switch recombination (CSR) of the Ig gene through the production of U:G mismatches in DNA, and is primarily found in activated B cells. AID expression has also been observed in several varying types of B cell lymphomas such as; Burkitt’s lymphoma, Hodgkin’s lymphoma, hairy cell lymphoma, follicular lymphoma, mantle cell lymphoma, mucosa-associated lymphoid tissue lymphoma, and mediastinal B cell lymphoma. Mutations in AID expression are causal to autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2), which is characterized by serum containing IgM but lacking IgG, IgA and IgE, which leads to severe susceptibility to bacterial infections.

General readings

1. Muramatsu, M. et al. (1999) Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells*. J. Biol. Chem. 274: 18470-18476.
2. Muramatsu, M. et al. (2000) Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme. Cell. 102:
553-563.
3. Yu, K. et al. (2005) Fine-structure analysis of activation-induced deaminase accessibility to class switch region R-loops. Mol. and Cell. Biol. 25: 1730-1736

17 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

AICDA / AID (N-term) antibody

TA303351 (0.1µg/ml) staining of Human Tonsil lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Bov, Hu, Por E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

AICDA / AID antibody

Western blot analysis of AID in Ramos whole cell lysate with AID antibody at 2 ug/mL in either the (A) absence or (B) presence of blocking peptide. Rabbit IgG Aff - Purified Hu, Ms E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

AICDA / AID (C-term) antibody

Skeletal Muscle: Formalin-Fixed Paraffin-Embedded (FFPE) using AICDA antibody Rabbit Aff - Purified Hu, Ms ICC/IF, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

AICDA / AID Control Peptide

AICDA / AID
50 µg / €160.00
  Acris Antibodies GmbH

AICDA / AID antibody

Tonsil stained in IHC-P with AICDA antibody Rabbit Purified Hu, Ms, Rt E, P, WB
0.1 mg / €420.00
  Acris Antibodies GmbH

AICDA / AID (C-term) antibody

Immunocytochemical staining of Ramos cells with Rabbit anti Human AID (SP2150P) Rabbit Aff - Purified Hu, Ms ICC/IF, WB
0.1 mg / €360.00
  Acris Antibodies GmbH

AICDA / AID (C-term) antibody

Immunocytochemical staining of Ramos cells with Rabbit anti Human AID (SP2150P) Rabbit IgG Aff - Purified Hu, Ms ICC/IF, WB
50 µg / €300.00
  Acris Antibodies GmbH

AICDA / AID antibody

Western Blot analysis of AICDA expression in transfected 293T cell line (H00057379-T02) by AICDA MaxPab polyclonal antibody.

Lane 1: AICDA transfected lysate(24.00 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

AICDA / AID antibody

Western blot analysis of cell lysates of HepG2 ( 60 µg ) and Ramos ( 60 µg ) were resolved by SDS - PAGE , transferred to NC membrane and probed with AICDA monoclonal antibody , clone 2D3 ( 1 : 500 ) ( Cat # MAB1107 ) . Proteins were visualized using a goat anti - mouse secondary antibody conjugated to HRP and an ECL detection system. Mouse IgG1 2D3 Hu E, WB
0.1 ml / €390.00
  Abnova Taiwan Corp.

AICDA / AID antibody

AICDA / AID Rabbit Ms E, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

AICDA / AID antibody

AICDA / AID Rabbit Ms E, WB
0.1 mg / €470.00
  Abnova Taiwan Corp.

AICDA / AID antibody

AICDA polyclonal antibody ( Cat # PAB7460 ) ( 0.1 µg/ml ) staining of human tonsil lysate ( 35 µg protein in RIPA buffer ) . Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

AICDA / AID antibody

Immunocytochemistry of AICDA in Ramos cells with AICDA polyclonal antibody ( Cat # PAB12893 ) at 10 µg/ml. Rabbit Hu, Ms ICC/IF, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

AICDA / AID (1-198, His-tag)

AICDA / AID Human Purified > 85 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

AICDA / AID (1-198, His-tag)

AICDA / AID Human Purified > 85 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

AICDA / AID

AICDA / AID Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

AICDA / AID

AICDA / AID Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

17 Item(s)

per page
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