AIP / XAP2 antibody

Principal name

AIP / XAP2 antibody

Alternative names for AIP / XAP2 antibody

AH receptor-interacting protein, ARA9, Aryl-hydrocarbon receptor-interacting protein, Immunophilin homolog ARA9, HBV X-associated protein 2

SwissProt ID

O00170 (Human), O08915 (Mouse), Q5FWY5 (Rat), Q7YRC1 (Bovin)

Gene ID

11632 (Aip), 9049 (AIP)

Available reactivities

Ms (Mouse), Hu (Human), Rt (Rat), Bov (Bovine), Can (Canine), Chk (Chicken), Ze (Zebrafish), Eq (Equine), GP (Guinea Pig), Por (Porcine), Sh (Sheep)

Available hosts

Rabbit, Mouse, Goat

Available applications

Western blot / Immunoblot (WB), ChIP assay (ChIP), Immunoprecipitation (IP), Paraffin Sections (P), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F)

Background of AIP / XAP2 antibody

The Aryl hydrocarbon receptor (AhR), also designated dioxin receptor (DR), a ligand-activated transcription factor, becomes activated upon binding of dioxins or structurally related forms of xenobiotics. Upon ligand binding, AhR translocates from the cytoplasm to the nucleus where it complexes with Arnt to form a DNA binding heterodimer. This complex activates transcription of target genes involved in xenobiotic metabolism. Until ligand binding occurs, AhR remains latent in the cytoplasm, which is maintained by its association with the molecular chaperones HSP 90, the hepatitis B virus X-associated protein (XAP2, also designated AIP and ARA9) and the heat shock protein p23. XAP2, a ubiquitously expressed protein, binds to HSP 90 and AhR through a highly conserved carboxy-terminal tetraticopeptide repeat domain. XAP2 participates in stabilizing AhR as well as enhancing the cytoplasmic localization of the receptor. It may also be involved in regulating the degradation of AhR.

General readings

Vierimaa O, Georgitsi M, Lehtonen R, Vahteristo P, Kokko A, Raitila A, Tuppurainen K, Ebeling TM, Salmela PI, Paschke R, Gundogdu S, De Menis E, Makinen MJ, Launonen V, Karhu A, Aaltonen LA. Pituitary adenoma predisposition caused by germline mutations in the AIP gene. Science. 2006 May 26;312(5777):1228-30. PMID: 16728643

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

AIP / XAP2 antibody

(A) HEK 293T/17 cells, Lane 1: IP ARA9, WB ARA9; Lane 2: WB ARA9 with whole cell lysate; (B) Detection of Ara9 in mouse lung lysates (30ug) using NB 100-127 at 1:500 with a 1 second exposure Mouse IgG1 35-2 Purified Hu, Ms WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

AIP / XAP2 (C-term) antibody

TA302405 (0.02µg/ml) staining of NIH/3T3 cell lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Can, Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

AIP / XAP2 antibody

ARA9 antibody [N1C3] detects ARA9 protein by Western blot analysis. A. 30 ug HeLa whole cell lysate/extract. B. 30 ug Molt-4 whole cell lysate/extract. C. 30 ug Raji whole cell lysate/extract. 10 % SDS-PAGE. ARA9 antibody [N1C3] (TA308832) dilution: 1:500 Rabbit IgG Aff - Purified Hu, Ms ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

AIP / XAP2 antibody

WB Suggested Anti-AIP Antibody Titration: 1.25ug/ml; ELISA Titer: 1:1562500; Positive Control: Jurkat cell lysateAIP is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rt, Sh, Ze WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

AIP / XAP2 antibody

WB Suggested Anti-AIP Antibody Titration: 2.5 ug/ml; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rt, Ze P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

AIP / XAP2 antibody

WB Suggested Anti-Aip Antibody Titration: 0.2-1 ug/ml; Positive Control: SP2/0 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

AIP / XAP2 antibody

WB Suggested Anti-AIP Antibody Titration: 1.25 ug/ml; ELISA Titer: 1:312500; Positive Control: NIH/3T3 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rt, Ze WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

AIP / XAP2 antibody

WB Suggested Anti-AIP Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: Jurkat cell lysateAIP is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells Rabbit IgG Purified Bov, Can, Eq, Hu, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

AIP / XAP2 antibody

WB Suggested Anti-AIP Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: OVCAR-3 cell lysate Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

AIP / XAP2 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY AIP (RC211157, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-AIP. Mouse IgG1 OTI1B6 Purified Hu F, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

AIP / XAP2 antibody

ELISA: AIP/ARA9  Antibody Rabbit IgG Purified Hu E
50 µg / €325.00
  OriGene Technologies, Inc.

AIP / XAP2 (310-323) antibody

Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) Goat IgG Aff - Purified Bear, Bov, Bt, Can, Elephant, Eq, Hst, Hu, Mky, Ms, Por, Prim, Rt E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

AIP / XAP2 antibody

AIP / XAP2 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

AIP / XAP2 antibody

AIP monoclonal antibody (M02), clone 3D3. Western Blot analysis of AIP expression in HepG2(Cat # L019V1 ). Mouse IgG1 3D3 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

AIP / XAP2 antibody

Western blot analysis of AIP in mouse lung lysates ( 30µg ) using AIP monoclonal antibody, clone 35-2 ( Cat # MAB2382 ) at 1 : 500 with a 1 second exposure. Mouse IgG1 35-2 Hu, Ms, Rt IP, WB
0.1 ml / €470.00
  Abnova Taiwan Corp.

AIP / XAP2 antibody

293 overexpressing AIP and probed with AIP polyclonal antibody ( Cat # PAB7275 ) ( mock transfection in first lane), tested by Origene. Goat Hu, Ms E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

AIP / XAP2 antibody

Human kidney; AIP antibody - N-terminal region (ARP35710_T100) in Human kidney cells using Immunohistochemistry Rabbit IgG Purified Bov, Can, Chk, Hu, Ms, Rt, Ze P, WB
0.1 mg / €310.00
  AVIVA Systems Biology

AIP / XAP2 antibody

Mouse SP2/0; WB Suggested Anti-Aip Antibody Titration: 0.2-1 ug/ml. Positive Control: SP2/0 cell lysate; Aip antibody - middle region (ARP37218_P050) in Mouse SP2/0 cells using Western Blot Rabbit Aff - Purified Ms WB
50 µg / €350.00
  AVIVA Systems Biology

AIP / XAP2 antibody

Mouse NIH-3T3; WB Suggested Anti-AIP Antibody Titration: 1.25ug/ml. ELISA Titer: 1:312500. Positive Control: NIH/3T3 cell lysate; AIP antibody - N-terminal region (ARP37219_T100) in Mouse NIH-3T3 cells using Western Blot Rabbit Aff - Purified Bov, Can, Chk, Hu, Ms, Rt WB
0.1 mg / €310.00
  AVIVA Systems Biology

AIP / XAP2 antibody

Human Jurkat; WB Suggested Anti-AIP Antibody Titration: 1.25ug/ml. ELISA Titer: 1:1562500. Positive Control: Jurkat cell lysate. AIP is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells.; AIP antibody - N-terminal region (ARP37734_T100) in Human Jurkat cells using Western Blot Rabbit IgG Purified Bov, Can, Chk, Hu, Ms, Rt, Ze WB
0.1 mg / €310.00
  AVIVA Systems Biology

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