AKAP5 antibody

Principal name

AKAP5 antibody

Alternative names for AKAP5 antibody

AKAP79, A-kinase anchor protein 5, A-kinase anchor protein 79 kDa, cAMP-dependent protein kinase regulatory subunit II high affinity-binding protein

SwissProt ID

P24275 (Bovin), P24587 (Rat), P24588 (Human)

Gene ID

9495 (AKAP5), 171026 (Akap5)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Ms (Mouse), Rt (Rat), Mky (Monkey)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP)

Background of AKAP5 antibody

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. AKAP5 is a member of the AKAP family. It binds to the RII-beta regulatory subunit of PKA, and also to protein kinase C and the phosphatase calcineurin. It is predominantly expressed in cerebral cortex and may anchor the PKA protein at postsynaptic densities (PSD) and be involved in the regulation of postsynaptic events. It is also expressed in T lymphocytes and may function to inhibit interleukin-2 transcription by disrupting calcineurin-dependent dephosphorylation of NFAT.The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to the RII-beta regulatory subunit of PKA, and also to protein kinase C and the phosphatase calcineurin. It is predominantly expressed in cerebral cortex and may anchor the PKA protein at postsynaptic densities (PSD) and be involved in the regulation of postsynaptic events. It is also expressed in T lymphocytes and may function to inhibit interleukin-2 transcription by disrupting calcineurin-dependent dephosphorylation of NFAT. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Lu,R. (2008) J. Biol. Chem. 283 (17), 11445-11452

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

AKAP5 antibody

  Rabbit Polyclonal Anti-AKAP5 Antibody  
WB Suggested Anti-AKAP5 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: Human Muscle Rabbit Aff - Purified Bov, Can, Hu, Ms, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

AKAP5 antibody

Immunofluorescence analysis of HeLa cells, using AKAP5 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF, WB
50 µg / €230.00
  Assay Biotech

AKAP5 antibody

Immunofluorescence analysis of HeLa cells, using AKAP5 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

AKAP5 - human gene knockout kit via CRISPR

AKAP5 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

AKAP5 - human gene knockout kit via CRISPR

AKAP5 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

AKAP5 - human gene knockout kit via CRISPR

AKAP5 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

AKAP5 - human gene knockout kit via CRISPR

AKAP5 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, AKAP5 (mGFP-tagged) - Human A kinase (PRKA) anchor protein 5 (AKAP5), 200 uL, >10^7 TU/mL

Lenti ORF particles, AKAP5 (mGFP-tagged) - Human A kinase (PRKA) anchor protein 5 (AKAP5), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, AKAP5 (Myc-DDK tagged) - Human A kinase (PRKA) anchor protein 5 (AKAP5) , 200 uL, >10^7 TU/mL

Lenti ORF particles, AKAP5 (Myc-DDK tagged) - Human A kinase (PRKA) anchor protein 5 (AKAP5) , 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Akap5 (GFP-tagged ORF) - Rat A kinase (PRKA) anchor protein 5 (Akap5), 200 uL, >10^7 TU/mL

Lenti ORF particles, Akap5 (GFP-tagged ORF) - Rat A kinase (PRKA) anchor protein 5 (Akap5), 200 uL, >10^7 TU/mL  
200 µl / €1,400.00
  OriGene Technologies, Inc.

Lenti ORF particles, Akap5 (Myc-DDK-tagged ORF) - Rat A kinase (PRKA) anchor protein 5 (Akap5), 200 uL, >10^7 TU/mL

Lenti ORF particles, Akap5 (Myc-DDK-tagged ORF) - Rat A kinase (PRKA) anchor protein 5 (Akap5), 200 uL, >10^7 TU/mL  
200 µl / €1,258.00
  OriGene Technologies, Inc.

11 Item(s)

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