AKR1A1 / ALDR1 antibody

Principal name

AKR1A1 / ALDR1 antibody

Alternative names for AKR1A1 / ALDR1 antibody

Aldehyde reductase, ALR, Aldo-keto reductase family 1 member A1, Alcohol dehydrogenase [NADP+]

SwissProt ID

P14550 (Human), P50578 (Pig), P51635 (Rat), Q3ZCJ2 (Bovin), Q9JII6 (Mouse)

Gene ID

10327 (AKR1A1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Por (Porcine), Bov (Bovine), Can (Canine)

Available hosts

Rabbit, Goat, Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), ELISA (detection) (E(detection)), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of AKR1A1 / ALDR1 antibody

Catalyzes the NADPH-dependent reduction of a variety of aromatic and aliphatic aldehydes to their corresponding alcohols. Catalyzes the reduction of mevaldate to mevalonic acid and of glyceraldehyde to glycerol. Has broad substrate specificity. In vitro substrates include succinic semialdehyde, 4-nitrobenzaldehyde, 1,2-naphthoquinone, methylglyoxal, and D-glucuronic acid. Plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs, including the anthracyclines doxorubicin (DOX) and daunorubicin (DAUN).Tissue specificity:Widely expressed. Highly expressed in kidney, salivary gland and liver. Detected in trachea, stomach, brain, lung, prostate, placenta, mammary gland, small intestine and lung.

General readings

Fujii J, Hamaoka R, Matsumoto A, Fujii T, Yamaguchi Y, Egashira M, Miyoshi O, Niikawa N, Taniguchi N.
The structural organization of the human aldehyde reductase gene, AKR1A1, and mapping to chromosome 1p33-->p32.
Cytogenet Cell Genet. 1999;84(3-4):230-2.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

AKR1A1 / ALDR1 antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of liver tissue using anti-AKR1A1mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500740, Dilution 1:50) Mouse IgG2a OTI9F1 Purified Hu F, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

AKR1A1 / ALDR1 antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of liver tissue using anti-AKR1A1mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500741, Dilution 1:50) Mouse IgG1 OTI8E12 Purified Hu F, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

AKR1A1 / ALDR1 antibody

Immunohistochemical staining of paraffin-embedded colon tissue within the normal limits using anti-AKR1A1mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500742, Dilution 1:50) Mouse IgG2a OTI2E7 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

AKR1A1 / ALDR1 antibody

Immunohistochemical staining of paraffin-embedded liver tissue within the normal limits using anti-AKR1A1mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500743, Dilution 1:50) Mouse IgG2b OTI8H2 Purified Hu F, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

AKR1A1 / ALDR1 antibody

Immunohistochemical staining of paraffin-embedded Human colon tissue within the normal limits using anti-AKR1A1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500744) Mouse IgG2b OTI10E11 Purified Hu F, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

AKR1A1 / ALDR1 antibody

Immunohistochemical staining of paraffin-embedded liver tissue within the normal limits using anti-AKR1A1mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500745, Dilution 1:50) Mouse IgG2a OTI6E3 Purified Hu F, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

AKR1A1 / ALDR1 antibody

Immunohistochemical staining of paraffin-embedded liver tissue within the normal limits using anti-AKR1A1mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500746, Dilution 1:50) Mouse IgG2b OTI4G2 Purified Hu F, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

AKR1A1 / ALDR1 antibody

Immunohistochemical staining of paraffin-embedded Kidney tissue within the normal limits using anti-AKR1A1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500810, Dilution 1:50) Mouse IgG2a OTI4G6 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

AKR1A1 / ALDR1 antibody

Immunoperoxidase of monoclonal antibody to AKR1A1 on formalin-fixed paraffin-embedded human tonsil. [antibody concentration 0.75 ug/ml] Mouse IgG1 1A11-2A4 Purified Hu E, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

AKR1A1 / ALDR1 (C-term) antibody

TA302408 (0.1µg/ml) staining of Human Liver lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Por, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

AKR1A1 / ALDR1 antibody

Western blot analysis of human fetal liver lysates with anti-AKR1A1 antibody (1:500). This antibody identified a band of ~37kDa in human fetal liver lysates. Rabbit Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

AKR1A1 / ALDR1 antibody

Predicted band size: 37 kDa. Positive control: Human liver cancer tissue, hela cell and human fetal kidney tissue lysate. Recommended dilution: 1/500-2000. (Gel: 10%SDS-PAGE Lane1: Human liver cancer tissue lysate Lane2: Hela cell lysate Lane3: Human fetal kidney tissue lysate Lysate: 27 ug per lane Primary antibody: 1/450 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 10 seconds) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

AKR1A1 / ALDR1 antibody

Predicted band size: 37 kDa. Positive control: Human liver cancer tissue, hela and 293T cell lysate. Recommended dilution: 1/500-2000. (Gel: 10%SDS-PAGE Lane1: Human liver cancer tissue lysate Lane2: Hela cell lysate Lane3: 293T cell lysate Lysates: 27 ug per lane Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 10 seconds) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

AKR1A1 / ALDR1 antibody

Western blot analysis of extracts from COLO205 cells and NIH-3T3 cells, using AKR1A1 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

AKR1A1 / ALDR1 antibody

Western blot analysis of extracts of various cell lines, using AKR1A antibody. Rabbit IgG Purified Hu, Ms, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

AKR1A1 / ALDR1 antibody

Immunohistochemical staining of paraffin-embedded liver tissue within the normal limits using anti-AKR1A1mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500767, Dilution 1:50) Mouse IgG2a OTI3C7 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

AKR1A1 / ALDR1 (313-325) antibody

Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) Goat Aff - Purified Bov, Bt, Can, Chk, Elephant, Eq, Fi, Hst, Hu, Mky, Ms, Op, Platypus, Por, Prim, Rb, Rt, Tr, Xen E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

AKR1A1 / ALDR1 (C-term) antibody

Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with AKR1A1 antibody (C-term) (Cat.#AP12362PU-N), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

AKR1A1 / ALDR1 antibody

AKR1A1 MaxPab polyclonal antibody. Western Blot analysis of AKR1A1 expression in human liver. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

AKR1A1 / ALDR1 antibody

AKR1A1 / ALDR1 Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

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