AKR1C2 / DDH2 antibody

Principal name

AKR1C2 / DDH2 antibody

Alternative names for AKR1C2 / DDH2 antibody

3-alpha-HSD3, Dihydrodiol dehydrogenase 2, Aldo-keto reductase family 1 member C2, Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase, Type III 3-alpha-hydroxysteroid dehydrogenase, Dihydrodiol dehydrogenase/bile acid-binding protein, Chlordecone reductase homolog HAKRD

SwissProt ID

P52895 (Human)

Gene ID

1646 (AKR1C2)

Available reactivities

Hu (Human), Mam (Mammalia), Ms (Mouse), Por (Porcine), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit), Rt (Rat), Sh (Sheep)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), ELISA (detection) (E(detection)), Immunoprecipitation (IP)

Background of AKR1C2 / DDH2 antibody

DDH is a member of aldo-keto reductase superfamily (1,2), which catalyzes reduction of aldehyde or ketone to a corresponding alcohol by using NADH or NADPH as a cofactor. In liver, the enzyme is abundantly located in the cytoplasm as a monomeric 34-36 kDa protein (3,4). Interestingly, by differential display Shen et al. (5) has shown that overexpression of DDH could be identified in ethacrynic acid-induced drug-resistant human colon cancer cells. Detection of DDH overexpression in drug-resistant human stomach cancer cells, which were selected by the gradual adaptation to daunorubicin, further suggested that DDH might be associated with the drug-resistance in cancer cells (6). In a recent study, DDH expression was further shown to have prognostic significance in patients with NSCLC. By using an immunohistochemical method to determine DDH expression in surgical specimens, DDH expression was identified in patients with leukemia, lung cancer, esophageal cancer, transitional cancer and breast cancer. Furthermore, overexpression of DDH was confirmed by immunoblotting and in situ hybridization. Correlation between clinicopathological parameters and DDH expression as well as the prognostic significance of DDH expression in patients with advanced cancer was indicated.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

AKR1C2 / DDH2 antibody

Western blot analysis of extracts from COLO cells, using AKR1C2 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

AKR1C2 / DDH2 antibody

WB Suggested Anti-AKR1C2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: MCF7 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Sh WB
50 µg / €325.00
  OriGene Technologies, Inc.

AKR1C2 / DDH2 antibody

WB Suggested Anti-AKR1C2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: MCF7 cell lysate Rabbit IgG Purified Bov, Eq, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

AKR1C2 / DDH2 antibody

Figure 1. Immunoperoxidase staining of formalin-fixed paraffin embedded human lung cancer tissue showing cytoplasmic localization of dihydrodiol dehydrogenase. Mouse IgG1 T101 Hu, Mam, Ms, Por E, ICC/IF, P, WB
0.1 ml / €490.00
  Acris Antibodies GmbH

AKR1C2 / DDH2 (C-term) antibody

AKR1C2 Antibody (C-term) (Cat. #AP50131PU-N)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of AKR1C2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

AKR1C2 / DDH2 antibody

Western Blot analysis of AKR1C2 expression in transfected 293T cell line by AKR1C2 polyclonal antibody (A01).

Lane1:AKR1C2 transfected lysate(37 KDa).
Lane2:Non-transfected lysate. Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

AKR1C2 / DDH2 antibody

AKR1C2 MaxPab polyclonal antibody. Western Blot analysis of AKR1C2 expression in human liver. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

AKR1C2 / DDH2 antibody

AKR1C2 / DDH2 Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

AKR1C2 / DDH2 antibody

AKR1C2 / DDH2 Mouse Hu WB
50 µg / €370.00
  Abnova Taiwan Corp.

AKR1C2 / DDH2 antibody

AKR1C2 / DDH2 Rabbit Serum Hu E(detection), IP, WB
0.1 ml / €380.00
  Abnova Taiwan Corp.

AKR1C2 / DDH2 antibody

AKR1C2 MaxPab rabbit polyclonal antibody. Western Blot analysis of AKR1C2 expression in human liver. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

AKR1C2 / DDH2 antibody

Detection limit for recombinant GST tagged AKR1C2 is approximately 0.3ng/ml as a capture antibody. Mouse IgG2a 3C11 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

AKR1C2 / DDH2 antibody

AKR1C2 / DDH2 Mouse IgG2a 3C11 Ascites Hu E, WB
0.2 ml / €370.00
  Abnova Taiwan Corp.

AKR1C2 / DDH2 antibody

Western blot analysis of extracts from COLO cells, using AKR1C2 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
50 µg / €205.00
  Assay Biotech

AKR1C2 / DDH2 antibody

Western blot analysis of extracts from COLO cells, using AKR1C2 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
0.1 mg / €310.00
  Assay Biotech

AKR1C2 / DDH2 antibody

AKR1C2 / DDH2 Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

AKR1C2 / DDH2 antibody

AKR1C2 / DDH2 Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

AKR1C2 / DDH2 antibody

Western Blot: AKR1C2 Antibody [NBP1-57769] - This Anti-AKR1C2 antibody was used in Western Blot of MCF7       tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

AKR1C2 / DDH2 antibody

Western Blot: AKR1C2 Antibody [NBP1-57770] - This Anti-AKR1C2 antibody was used in Western Blot of MCF7       tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu WB
50 µg / €440.00
  Novus Biologicals Inc.

AKR1C2 / DDH2 antibody

AKR1C2 / DDH2 Rabbit IgG Aff - Purified Hu E, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

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